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Categories: Biology: Biotechnology, Geoscience: Landslides

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A major new study reveals a 'traffic light' mechanism controlling genetic activity within cells -- a system which could potentially be targeted by cancer drugs already in development. The research describes how 'epigenetic' changes to the structure of DNA can act as a stop-go signal in determining whether a gene should be read. Unlike our genetic make-up, which is well understood, the world of epigenetics is still largely unexplored and referred to as the 'dark matter' of the genome.

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Submarine landslides have a large tsunami potential and occurred on the central Norwegian shelf more frequently in the past than previously thought. Scientists investigate the Nyegga landslide off the coast of Norway. The submarine landslide occurred in the same area as the well-known Storegga event 8,150 years ago. The new findings suggest that approximately one-third of the seafloor material missing -- previously attributed to the Storegga event -- was removed by the Nyegga event 20,000 years ago. This raises questions about the frequency of large submarine landslides and their associated tsunami hazard.

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A detailed atlas of gene expression in the zebrafish brain.

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Scientists thought a gold-throated hummingbird was a new species. DNA revealed that it's a hybrid of two different species, each with pink throats. The discovery sheds light on how birds produce feather colors and how hummingbirds evolved their dazzling hues.

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Researchers describe how gut-on-a-chip devices can bridge lab models and human biology. Modeling the microbiome is particularly difficult because of its unique environmental conditions, but through creative design, gut-on-a-chip devices can simulate many of these properties, such as the gut's anaerobic atmosphere, fluid flow, and pulses of contraction/relaxation. Growing intestinal cells in this environment means that they more closely resemble human biology compared to standard laboratory cell cultures.

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Biochemists have succeeded in resurrecting the ancestral genes of five detoxifying enzymes which are present in all tetrapods to show how their divergence in function has occurred.

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By simulating early Earth conditions in the lab, researchers have found that without specific amino acids, ancient proteins would not have known how to evolve into everything alive on the planet today -- including plants, animals, and humans.

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Textbooks will tell you that in dividing cells, production of new DNA peaks during the S-phase, while production of other macromolecules, such as proteins, lipids, and polysaccharides, continues at more or less the same level. Molecular biologists have now discovered that this is not true: protein synthesis shows two peaks and lipid synthesis peaks once.

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Haematopoietic stem cell transplantation for the treatment of severe blood cancers is the only medical intervention that has cured two people living with HIV in the past. An international group of physicians and researchers has now identified another case in which HIV infection has been shown to be cured in the same way. The successful healing process of this third patient was for the first time characterized in great detail virologically and immunologically over a time span of ten years.

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Influenza viruses are becoming increasingly resilient to medicines. For this reason, new active ingredients are needed. Important findings in this regard have been provided: for the virus to proliferate, the polymerase of the influenza A virus has to be modified many times through enzymes in the host cells. The team of researchers was able to produce a comprehensive map of types of modification. Medicines directed against the enzymes woud be resilient to rapid mutations in the virus, thus offering great potential for the future.

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A team has developed a method for selectively manipulating genetically engineered cells with ultrasound.

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Las Vegas, with its rapid urbanization and desert landscape, is highly vulnerable to flooding. For this reason, flood managers have built an extensive system of drainage ditches and detention basins to protect the public. Now, a new study shows how intentional engineering and urban development are interacting with climate change to alter the timing and intensity of flood risk.

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A new modelling study shows that the Seychelles and other islands in the western Indian Ocean are not responsible for most of the plastic waste that accumulates on their beaches. Indonesia, India, and Sri Lanka were found to be the main sources of land-based plastic debris. The Seychelles also accumulate significant amounts of plastic debris of marine origin from fisheries and shipping lanes. • The results highlight the urgent need for a legally-binding Global Plastics Treaty and greater enforcement of regional policies to reduce plastic waste.

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Supporters of the large-scale Mississippi River sediment diversions currently being planned by the Louisiana Coastal Protection and Restoration Authority got a boost to their case recently when scientists published an analysis of two existing freshwater diversions on the state's coastline, one of which shows a significant amount of land having formed over the past 17 years.

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Satellite observations have revealed that weak seismic ground shaking can trigger powerful landslide acceleration -- even several years after a significant earthquake.

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Scientists have found a new and better way to use remote sensing to understand where coastal dead zones are and predict changes.

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On March 11, 2011, multiple catastrophes in Japan were triggered by the Great East Japan Earthquake, including the nuclear accident at the Fukushima Daiichi Nuclear Power Plant. This event, also known as the 3/11 disaster, is what is known as a compound disaster. Now that over a decade has passed since this event, researchers are investigating how to prevent the next compound disaster.

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Subduction zones, where one tectonic plate slides beneath another, produce the most devastating seismic, volcanic, and landslide hazards on the planet. A new report presents an ambitious plan to make major advances in understanding subduction zone hazards by bringing together a diverse community of scientists in a long-term collaborative effort, deploying new instrumentation in subduction zones, and developing more sophisticated and accurate models.

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A devastating fire followed by an intense rainstorm triggered mudslides in Southern California in 2018 that claimed 23 lives. New findings elucidate the physics behind the deadly disaster that may inform predictive models of future mudslides.

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Rapidly evolving floods are a major and growing hazard worldwide. Currently, their onset and evolution is hard to identify using existing systems. However, seismic sensors already in place to detect earthquakes could be a solution to this problem. Researchers show that a seismometer can sense a flood, such as the devastating one that hit Germany in July 2021, up to 1.5 km away. This could act as an early warning to save lives and lessen damage. They also found that being able to measure the 'seismic footprint' of the flood provides information on its magnitude, velocity and trajectory in real time, which could be used for future flood protection.