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Categories: Biology: Biotechnology, Geoscience: Landslides
Published Study links 'stuck' stem cells to hair turning gray
(via sciencedaily.com) Original source Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.
Published Loops, flags and tension in DNA
(via sciencedaily.com) Original source Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they have visualized this.
Published New mechanism for DNA folding
(via sciencedaily.com) Original source A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.
Published Novel nanocages for delivery of small interfering RNAs
(via sciencedaily.com) Original source Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation between the Universities of Amsterdam and Leiden, researchers have developed dedicated molecular nanocages for siRNA delivery. In a paper just out in the Journal Chem they present nanocages that are easy to prepare and display tuneable siRNA delivery characteristics.
Published Fluorescent blue coumarins in a folk-medicine plant could help us see inside cells
(via sciencedaily.com) Original source Plants that glow under ultraviolet (UV) light aren't only a figment of science fiction TV and movies. Roots of a traditional medicine plant called the orange climber, or Toddalia asiatica, can fluoresce an ethereal blue hue. And now, researchers have identified two coumarin molecules that could be responsible. These natural coumarins have unique fluorescent properties, and one of the compounds could someday be used for medical imaging.
Published SpyLigation uses light to switch on proteins
(via sciencedaily.com) Original source Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail. This technology has potential uses in tissue engineering, regenerative medicine, and understanding how the body works. The scientists applied their new method to control the glow of a green fluorescent protein derived from Japanese eel muscle.
Published Coastal species persist on high seas on floating plastic debris
(via sciencedaily.com) Original source The high seas have been colonized by a surprising number of coastal marine invertebrate species, which can now survive and reproduce in the open ocean, contributing strongly to the floating community composition. Researchers found coastal species, representing diverse taxonomic groups and life history traits, in the eastern North Pacific Subtropical Gyre on over 70 percent of the plastic debris they examined. Further, the debris carried more coastal species than open ocean species.
Published New genetic target for male contraception identified
(via sciencedaily.com) Original source Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals. Researchers identified expression of the gene, Arrdc5, in the testicular tissue of mice, pigs, cattle and humans. When they knocked out the gene in mice, it created infertility only in the males, impacting their sperm count, movement and shape.
Published How a virus causes chromosomal breakage, leading to cancer
(via sciencedaily.com) Original source Researchers describe how the Epstein-Barr virus exploits genomic weaknesses to cause cancer while reducing the body's ability to suppress it.
Published Study reveals how pollinators cope with plant toxins
(via sciencedaily.com) Original source Pollinators such as honeybees produce special enzymes that detoxify defence chemicals produced by plants, new research shows.
Published Where did the first sugars come from?
(via sciencedaily.com) Original source Origin-of-life chemists propose that glyoxylate could have been the original source of sugars on the 'prebiotic' Earth
Published Biologists determine the evolutionary age of individual cell types providing critical insights for animal development
(via sciencedaily.com) Original source A research team has recently made a significant discovery about the evolutionary age of different type of cells in a small animal called Caenorhabditis elegans (C. elegans). By using single-cell transcriptomic data and refined phylostratigraphy, the team determines the transcriptomic age of individual cells, which means they are able to estimate the evolutionary origin of different cells based on the age of the genes expressed in the cells.
Published Study compares de novo proteins with randomly produced proteins
(via sciencedaily.com) Original source In a series of experiments, a team of researchers have compared de novo proteins with random-sequence proteins, looking at their stability and solubility. The results are set to advance basic research in this new field.
Published Increased droughts are disrupting carbon-capturing soil microbes, concerning ecologists
(via sciencedaily.com) Original source Soil stores more carbon than plants and the atmosphere combined, and soil microbes are largely responsible for putting it there. However, the increasing frequency and severity of drought, such as those that have been impacting California, could disrupt this delicate ecosystem. Microbial ecologists warn that soil health and future greenhouse gas levels could be impacted if soil microbes adapt to drought faster than plants do.
Published How skates learned to fly through water
(via sciencedaily.com) Original source Genes are not the only drivers of evolution. The iconic fins of skates are caused by changes in the non-coding genome and its three-dimensional structure, an international research team reports.
Published Oral barrier is similar in ceramide composition to skin barrier
(via sciencedaily.com) Original source Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.
Published Genes are read faster and more sloppily in old age
(via sciencedaily.com) Original source Scientists have demonstrated the following findings which apply across the animal kingdom: with increasing age, the transcriptional elongation speed of genes increases, whereby the quality of the gene products suffers. With dietary restrictions, these processes could be reversed.
Published British flower study reveals surprise about plants' sex life
(via sciencedaily.com) Original source A study of Britain's native flowering plants has led to new insights into the mysterious process that allows wild plants to breed across species -- one of plants' most powerful evolutionary forces. When wild flowering plants are sizing up others they may often end up in a marriage between close relatives rather than neighbors, a new study has revealed.
Published New approach targets norovirus, world's leading cause of foodborne infection
(via sciencedaily.com) Original source Researchers have found a creative way to make a vaccine for norovirus, the leading cause of foodborne infections, by piggybacking on rotavirus, an unrelated virus for which there are already several highly effective vaccines.
Published Stowaways in the genome
(via sciencedaily.com) Original source Scientists have discovered over 30,000 viruses by using the high-performance computer cluster 'Leo' and sophisticated detective work. The viruses hide in the DNA of unicellular organisms. In some cases, up to 10% of microbial DNA consists of built-in viruses.