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Categories: Biology: Biotechnology, Geoscience: Geography
Published Researchers teaching artificial intelligence about frustration in protein folding
(via sciencedaily.com) Original source Scientists have found a new way to predict how proteins change their shape when they function, which is important for understanding how they work in living systems. While recent artificial intelligence (AI) technology has made it possible to predict what proteins look like in their resting state, figuring out how they move is still challenging because there is not enough direct data from experiments on protein motions to train the neural networks.
Published Incorporating humidity improves estimations of climate impacts on health
(via sciencedaily.com) Original source Governments, medical institutions and other bodies require accurate models on health-related matters in order to better organize their activities. Climate change has measurable impacts on society, including on human mortality. However, current models to assess the health impacts of climate change do not account for every environmental parameter, especially humidity, which could influence heat stress perceived by the human body, leaving room for improvement. Researchers have now incorporated humidity data from hundreds of cities into so-called heat stress indicators (HSIs) and assessed their performances in predicting heat-related deaths.
Published New worm study paves way for better RNA-based drugs to treat human disease
(via sciencedaily.com) Original source Researchers have discovered RNA mechanisms that may lead to more effective, durable and targeted treatments for conditions like high cholesterol, liver diseases and cancers.
Published Deadly sea snail toxin could be key to making better medicines
(via sciencedaily.com) Original source Scientists are finding clues for how to treat diabetes and hormone disorders in an unexpected place: a toxin from one of the most venomous animals on the planet.
Published Scientists discover new code governing gene activity
(via sciencedaily.com) Original source A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists' understanding of gene regulation and how genetic variations may influence gene expression in development or disease.
Published Researchers uncover the secrets of 'plant puberty'
(via sciencedaily.com) Original source Researchers have identified the genetic changes linked to why plants go through a developmental change similar to 'puberty' at different rates, a discovery which could lead to better crop nutrition.
Published Peering into the mind of artificial intelligence to make better antibiotics
(via sciencedaily.com) Original source Artificial intelligence (AI) has exploded in popularity as of late. But just like a human, it's hard to read an AI model's mind. Explainable AI (XAI) could help us do just that by providing justification for a model's decisions. And now, researchers are using XAI to scrutinize predictive AI models more closely, which could help make better antibiotics.
Published Forest loss intensifies climate change by increasing temperatures and cloud level, which leads to decrease of water
(via sciencedaily.com) Original source Researchers report that deforestation during the last two decades induced a higher warming and cloud level rise than that caused by climate change, which threatens biodiversity and water supply in African montane forests.
Published New insights on how bird flu crosses the species barrier
(via sciencedaily.com) Original source The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's polymerase when it interacts with a human protein essential for the virus to replicate within the cell. The structure of this replication complex provides important information about the mutations that avian influenza polymerase must undergo to adapt to mammals, including humans. These results can help scientists monitor the evolution and adaptability of bird flu strains, such as H5N1 or H7N9, towards infecting other species.
Published Searching old stem cells that stay young forever
(via sciencedaily.com) Original source The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists have now identified possible candidates for multipotent stem cells in the sea anemone for the first time. These stem cells are regulated by evolutionary highly conserved genes.
Published Preservation of organic carbon in the ocean floor
(via sciencedaily.com) Original source The preservation of organic carbon in marine sediments has long been a key question remaining unclear in understanding the long-term carbon cycling on Earth. Recently, scientists have gained new insights into the dynamic cycling of iron-bound organic carbon in subseafloor sediments.
Published Preliminary study shows potential of Manuka honey as a nutraceutical for breast cancer
(via sciencedaily.com) Original source A new study found that Manuka honey could potentially be an alternative, natural option for breast cancer prevention and treatment -- particularly for estrogen receptor (ER)-positive breast cancer, the most common subtype of breast cancer that accounts for about 70-80% of all breast cancer cases.
Published Ancient DNA reveals Indigenous dog lineages found at Jamestown, Virginia
(via sciencedaily.com) Original source Previous scientific studies have indicated that North American dog lineages were replaced with European ones between 1492 and the present day. To better understand the timing of this replacement, researchers sequenced mitochondrial DNA from archaeological dogs. Their findings suggest a complex social history of dogs during the early colonial period.
Published Nitrogen interventions as a key to better health and robust ecosystems
(via sciencedaily.com) Original source An international research team combined multidisciplinary methods to evaluate how nitrogen interventions could improve air quality and reduce nitrogen deposition. Their study found that interventions, such as improving fuel combustion conditions, increasing agricultural nitrogen use efficiency, and reducing food loss and waste, could significantly lower premature deaths attributed to air pollution, crop losses, and ecosystems risks.
Published Knocking out one key gene leads to autistic traits
(via sciencedaily.com) Original source Hyperactivity, repetitive behavior, and language deficits all appeared in the mice, highlighting an unexpected role the cerebellum seems to play in autism.
Published Decoding mysterious seismic signals
(via sciencedaily.com) Original source Geophysicists find link between seismic waves called PKP precursors and anomalies in Earth's mantle that are associated with hotspots associated with volcanism on the surface.
Published Scottish and Irish rocks confirmed as rare record of 'snowball Earth'
(via sciencedaily.com) Original source The study found that the Port Askaig Formation, composed of layers of rock up to 1.1 km thick, was likely laid down between 662 to 720 million years ago during the Sturtian glaciation -- the first of two global freezes thought to have triggered the development of complex, multicellular life.
Published As human activities expand in Antarctica, scientists identify crucial conservation sites
(via sciencedaily.com) Original source Establishing Key Biodiversity Areas in the Southern Ocean will be vital for safeguarding the ecosystem from the impact of human activities, researchers say.
Published Zebrafish use surprising strategy to regrow spinal cord
(via sciencedaily.com) Original source A new study maps out a detailed atlas of all the cells involved in regenerating the zebrafish spinal cord. In an unexpected finding, the researchers showed that survival and adaptability of the severed neurons themselves is required for full spinal cord regeneration. Surprisingly, the study showed that stem cells capable of forming new neurons play a complementary role but don t lead the process.
Published Surprise finding in study of environmental bacteria could advance search for better antibiotics
(via sciencedaily.com) Original source Researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial cell's 'envelope' or enclosure is key to its survival, the finding could advance the search for new and better antibiotics.