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Categories: Biology: Biotechnology, Geoscience: Earth Science
Published Complex impact of large wildfires on ozone layer dynamics



In a revelation highlighting the fragile balance of our planet's atmosphere, scientists have uncovered an unexpected link between massive wildfire events and the chemistry of the ozone layer. Using satellite data and numerical modeling, the team discovered that an enormous smoke-charged vortex nearly doubles the southern hemispheric aerosol burden in the middle stratosphere of the Earth and reorders ozone depletion at different heights. This study reveals how wildfires, such as the catastrophic 2019/20 Australian bushfires, impact the stratosphere in previously unseen ways.
Published New ways to study spinal cord malformations in embryos



Scientists have successfully created mechanical force sensors directly in the developing brains and spinal cords of chicken embryos, which they hope will improve understanding and prevention of birth malformations such as spina bifida.
Published High and low tide cause low and high methane fluxes



Methane, a strong greenhouse gas that naturally escapes from the bottom of the North Sea, is affected by the pressure of high or low tide. Methane emissions from the seafloor can be just easily three times as much or as little, depending on the tide, according to a new study.
Published A better way to make RNA drugs



RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste. Researchers report a new, enzyme-based RNA synthesis method that can produce strands of RNA with both natural and modified nucleotides without the environmental hazards.
Published Unprecedented warming threatens Earth's lakes and their ecosystems



Lakes, with their rich biodiversity and important ecological services, face a concerning trend: rapidly increasing temperatures. A recent study by limnologists and climate modelers reveals that if current anthropogenic warming continues until the end of this century, lakes worldwide will likely experience pervasive and unprecedented surface and subsurface warming, far outside the range of what they have encountered before.
Published A comprehensive derivative synthesis method for development of new antimicrobial drugs



A method to screen a wide variety of drug candidates without laborious purification steps could advance the fight against drug-resistant bacteria.
Published Study finds health risks in switching ships from diesel to ammonia fuel



Without additional regulation, burning ammonia in ship engines could cause serious impacts on air quality that could result in more than 600,000 additional premature deaths per year, according to new research.
Published Mapping the world's fungi from air samples



Researchers have found that the key to a quick and cost-effective mapping of biodiversity has been right in front of our eyes all along, but at the same time invisible -- i.e., in the air that surrounds us.
Published Opening the right doors: 'Jumping gene' control mechanisms revealed



International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of 'jumping genes.' DDM1 makes 'jumping genes' more accessible for transcription-suppressing chemical marks to be deposited. Because a variant of this protein exists in humans, the discovery provides insight into genetic conditions caused by such 'jumping gene' mutations.
Published First ever 3D reconstruction of 52,000-year-old woolly mammoth chromosomes thanks to serendipitously freeze-dried skin



An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted. This unprecedented level of structural detail was retained because the mammoth underwent freeze-drying shortly after it died, which meant that its DNA was preserved in a glass-like state.
Published New study provides enhanced understanding of tropical atmospheric waves



Findings has critical implications for predicting extreme weather events such as hurricanes and heavy rainfall.
Published Novel genome editing approach restores hearing in adult preclinical models with genetic deafness



Researchers restored hearing in preclinical mouse models with a specific form of inherited deafness called DFNA50 caused by mutations in microRNA, by using a novel in vivo CRISPR genome editing approach. Since mouse and human microRNAs have identical sequences, the researchers hope this work can one day be translated into applications for humans.
Published Atlas of proteins reveals inner workings of cells



Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design.
Published Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease



Acute graft-versus-host disease occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Researchers recently identified a bacteriophage-derived enzyme called endolysin capable of targeting biofilms formed by Enterococcus faecalis. Their findings offer hope for tailored interventions in allo-HCT.
Published The Gulf Stream is wind-powered and could weaken from climate change



New evidence of changes to the Gulf Stream during the last ice age could indicate additional sensitivity to future climatic changes, finds a new study.
Published Discovery could help reduce adverse side effects of popular next-generation obesity medications



By teasing apart the therapeutic benefits from the adverse effects of new generation obesity medications, researchers found a population of neurons in the brain that controls food intake without causing nausea in an animal model.
Published Big gain in battle against harmful bacteria



An unexpected find has enabled important progress to be made in the battle against harmful bacteria.
Published The plague may have caused the downfall of the Stone Age farmers



Ancient DNA from bones and teeth hints at a role of the plague in Stone Age population collapse. Contrary to previous beliefs, the plague may have diminished Europe's populations long before the major plague outbreaks of the Middle Ages, new research shows.
Published Cutting farm nitrous oxide emissions helps climate and ozone layer



Adding crushed basalt rocks and special fertilizers can reduce potent nitrous oxide (N2O) greenhouse gas emissions and help safeguard the stratospheric ozone layer.
Published New one-step method to make multiple edits to a cell's genome



A team of scientists have developed a new method that enables them to make precise edits in multiple locations within a cell -- all at once. Using molecules called retrons, they created a tool that can efficiently modify DNA in bacteria, yeast, and human cells.