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Categories: Biology: Biotechnology, Space: Exploration
Published Unlocking the mystery of preexisting drug resistance: New study sheds light on cancer evolution



The evolution of resistance to diseases, from infectious illnesses to cancers, poses a formidable challenge. Despite the expectation that resistance-conferring mutations would dwindle in the absence of treatment due to a reduced growth rate, preexisting resistance is pervasive across diseases that evolve -- like cancer and pathogens -- defying conventional wisdom.
Published NASA's Webb investigates eternal sunrises, sunsets on distant world



Researchers using NASA's James Webb Space Telescope have finally confirmed what models have previously predicted: An exoplanet has differences between its eternal morning and eternal evening atmosphere. WASP-39 b, a giant planet with a diameter 1.3 times greater than Jupiter, but similar mass to Saturn that orbits a star about 700 light-years away from Earth, is tidally locked to its parent star. This means it has a constant dayside and a constant nightside -- one side of the planet is always exposed to its star, while the other is always shrouded in darkness.
Published Scorching storms on distant worlds revealed



An international study reveals the extreme atmospheric conditions on the celestial objects, which are swathed in swirling clouds of hot sand amid temperatures of 950C. Using NASA's powerful James Webb Space Telescope (JWST), researchers set out to capture the weather on a pair of brown dwarfs -- cosmic bodies that are bigger than planets but smaller than stars.
Published JWST unveils stunning ejecta and CO structures in Cassiopeia A's young supernova



Researchers announced the latest findings from the James Webb Space Telescope (JWST) of the supernova remnant, Cassiopeia A (Cas A). These observations of the youngest known core collapse supernova in the Milky Way provide insights into the conditions that lead to the formation and destruction of molecules and dust within supernova ejecta. The study's findings change our understanding of dust formation in the early universe in the galaxies detected by JWST 300 million years after the Big Bang.
Published Building a roadmap to bioengineer plants that produce their own nitrogen fertilizer



Nitrogen fertilizers make it possible to feed the world's growing population, but they are also costly adn harm ecosystems. However, a few plants have evolved the ability to acquire their own nitrogen with the help of bacteria, and a new study helps explain how they did it, not once, but multiple times.
Published Cosmic wrestling match



Our universe is around 13.8 billion years old. Over the vastness of this time, the tiniest of initial asymmetries have grown into the large-scale structures we can see through our telescopes in the night sky: galaxies like our own Milky Way, clusters of galaxies, and even larger aggregations of matter or filaments of gas and dust. How quickly this growth takes place depends, at least in today's universe, on a sort of wrestling match between natural forces: Can dark matter, which holds everything together through its gravity and attracts additional matter, hold its own against dark energy, which pushes the universe ever further apart?
Published Big boost for new epigenetics paradigm: CoRSIVs, first discovered in humans, now found in cattle



A study opens new possibilities to improve production efficiency in the cattle industry and potentially animal agriculture more broadly.
Published Vivid portrait of interacting galaxies marks Webb's second anniversary



Two for two! A duo of interacting galaxies commemorates the second science anniversary of NASA's James Webb Space Telescope, which takes constant observations, including images and highly detailed data known as spectra. Its operations have led to a 'parade' of discoveries by astronomers around the world.
Published How domestic rabbits become feral in the wild



After sequencing the genomes of nearly 300 rabbits from Europe, South America, and Oceania, researchers found that all of them had a mix of feral and domestic DNA. They say this was not what they had expected to find.
Published New ways to study spinal cord malformations in embryos



Scientists have successfully created mechanical force sensors directly in the developing brains and spinal cords of chicken embryos, which they hope will improve understanding and prevention of birth malformations such as spina bifida.
Published A better way to make RNA drugs



RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste. Researchers report a new, enzyme-based RNA synthesis method that can produce strands of RNA with both natural and modified nucleotides without the environmental hazards.
Published A comprehensive derivative synthesis method for development of new antimicrobial drugs



A method to screen a wide variety of drug candidates without laborious purification steps could advance the fight against drug-resistant bacteria.
Published Scientific definition of a planet says it must orbit our sun; A new proposal would change that



The International Astronomical Union defines a planet as a celestial body that orbits the sun, is massive enough that gravity has forced it into a spherical shape, and has cleared away other objects near its orbit around the sun. Scientists now recognize the existence of thousands of planets, but the IAU definition applies only to those within our solar system. The new proposed definition specifies that the body may orbit one or more stars, brown dwarfs or stellar remnants and sets mass limits that should apply to planets everywhere.
Published Opening the right doors: 'Jumping gene' control mechanisms revealed



International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of 'jumping genes.' DDM1 makes 'jumping genes' more accessible for transcription-suppressing chemical marks to be deposited. Because a variant of this protein exists in humans, the discovery provides insight into genetic conditions caused by such 'jumping gene' mutations.
Published Dark matter in dwarf galaxy tracked using stellar motions



The qualities and behavior of dark matter, the invisible 'glue' of the universe, continue to be shrouded in mystery. Though galaxies are mostly made of dark matter, understanding how it is distributed within a galaxy offers clues to what this substance is, and how it's relevant to a galaxy's evolution.
Published First ever 3D reconstruction of 52,000-year-old woolly mammoth chromosomes thanks to serendipitously freeze-dried skin



An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted. This unprecedented level of structural detail was retained because the mammoth underwent freeze-drying shortly after it died, which meant that its DNA was preserved in a glass-like state.
Published Novel genome editing approach restores hearing in adult preclinical models with genetic deafness



Researchers restored hearing in preclinical mouse models with a specific form of inherited deafness called DFNA50 caused by mutations in microRNA, by using a novel in vivo CRISPR genome editing approach. Since mouse and human microRNAs have identical sequences, the researchers hope this work can one day be translated into applications for humans.
Published Mars likely had cold and icy past, new study finds



The question of whether Mars ever supported life has captivated the imagination of scientists and the public for decades. Central to the discovery is gaining insight into the past climate of Earth's neighbor: was the planet warm and wet, with seas and rivers much like those found on our own planet? Or was it frigid and icy, and therefore potentially less prone to supporting life as we know it? A new study finds evidence to support the latter by identifying similarities between soils found on Mars and those of Canada's Newfoundland, a cold subarctic climate.
Published Greater focus needed on how existing international law can prevent the increasing militarization of outer space



There is a pressing need for countries and international organizations to understand better how existing international law can help them address serious concerns about the militarization of outer space, a new study says.
Published Atlas of proteins reveals inner workings of cells



Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design.