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Categories: Biology: Biotechnology, Geoscience: Geology
Published Vitamin B6: New compound delays degradation
(via sciencedaily.com) Original source A low vitamin B6 level has negative effects on brain performance. A research team has now found a way to delay the degradation of the vitamin.
Published The genetic 'switches' of bone growth
(via sciencedaily.com) Original source In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone. They are controlled by other sequences in the genome, called enhancers, which, like switches, activate or deactivate them as required. A team has now identified and located 2700 enhancers -- among millions of non-coding genetic sequences -- that precisely regulate the genes responsible for bone growth. This discovery sheds light on one of the major factors influencing the size of individuals in adulthood, and explains why their failure could be the cause of certain bone malformations.
Published Scientists preserve DNA in an amber-like polymer
(via sciencedaily.com) Original source With their 'T-REX' method, researchers developed a glassy, amber-like polymer that can be used for long-term storage of DNA, such as entire human genomes or digital files such as photos.
Published The rotation of Earth's inner core has slowed, new study confirms
(via sciencedaily.com) Original source The new study provides unambiguous evidence that the inner core began to decrease its speed around 2010, moving slower than the Earth's surface.
Published Modifying genomes of tardigrades to unravel their secrets
(via sciencedaily.com) Original source Some species of tardigrades are highly and unusually resilient to various extreme conditions fatal to most other forms of life. The genetic basis for these exceptional abilities remains elusive. Researchers have now successfully edited genes using the CRISPR technique in a highly resilient tardigrade species previously impossible to study with genome-editing tools. The successful delivery of CRISPR to an asexual tardigrade species directly produces gene-edited offspring. The design and editing of specific tardigrade genes allow researchers to investigate which are responsible for tardigrade resilience and how such resilience can work.
Published Laser tests reveal new insights into key mineral for super-Earths
(via sciencedaily.com) Original source Scientists have for the first time observed how atoms in magnesium oxide morph and melt under ultra-harsh conditions, providing new insights into this key mineral within Earth's mantle that is known to influence planet formation.
Published A mountainous mystery uncovered in Australia's pink sands
(via sciencedaily.com) Original source Deposits of deep-pink sand washing up on South Australian shores shed new light on when the Australian tectonic plate began to subduct beneath the Pacific plate, as well as the presence of previously unknown ancient Antarctic mountains.
Published New technique reveals earliest signs of genetic mutations
(via sciencedaily.com) Original source Mutations are changes in the molecular 'letters' that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including cancer. Now, a new study introduces an original technique, called HiDEF-seq, that can accurately detect the early molecular changes in DNA code that precede mutations.
Published Scientists engineer yellow-seeded camelina with high oil output
(via sciencedaily.com) Original source Using tools of modern genetics, plant biochemists have produced a new high-yielding oilseed crop variety -- a yellow-seeded variety of Camelina sativa, a close relative of canola, that accumulates 21.4% more oil than ordinary camelina.
Published Virus-like nanoparticles control the multicellular organization and reproduction of host bacteria
(via sciencedaily.com) Original source Researchers have discovered that virus-like nanoparticles can promote the multicellular organization and reproduction of host bacteria. These particles, which are evolutionarily related to phages (viruses that infect bacteria), contain an enzyme that helps shape the multicellular architecture and ultimately enhances morphological differentiation.
Published Protein study could help researchers develop new antibiotics
(via sciencedaily.com) Original source A team has found a way to make the bacterial enzyme histidine kinase water-soluble, which could make it possible to rapidly screen potential antibiotics that might interfere with its functions.
Published How human derived RNA fragments help the Hepatitis E virus
(via sciencedaily.com) Original source Why does Hepatitis E become chronic in some patients, and why do medications not work? To find out, an international research team led by scientists from Bochum observed a patient with chronic Hepatitis E infection over a year. Repeated sequencing of the virus RNA showed that the virus incorporated various parts of the host's messenger RNA into its genome. This resulted in a replication advantage, which may have contributed to the infection becoming chronic.
Published Lung organoids unveil secret: How pathogens infect human lung tissue
(via sciencedaily.com) Original source How do pathogens invade the lungs? Using human lung microtissues, a team has uncovered the strategy used by a dangerous pathogen. The bacterium targets specific lung cells and has developed a sophisticated strategy to break through the lungs' line of defense.
Published The solar system may have passed through dense interstellar clouds 2 million years ago, altering Earth's climate
(via sciencedaily.com) Original source Astrophysicists calculate the likelihood that Earth was exposed to cold, harsh interstellar clouds, a phenomenon not previously considered in geologic climate models.
Published Novel Genetic Clock discovers oldest known marine plant
(via sciencedaily.com) Original source An international research team has discovered the oldest known marine plant using a novel genetic clock. This 1400-year-old seagrass clone from the Baltic Sea dates back to the Migration Period. The research project is a significant step towards better understanding and protecting marine ecosystems.
Published Cascadia Subduction Zone, one of Earth's top hazards, comes into sharper focus
(via sciencedaily.com) Original source A new study has produced the first comprehensive survey of the many complex structures beneath the seafloor in the Cascadia Subduction Zone, off British Columbia, Washington, Oregon and California. It is providing scientists with key insights into how future disasters may unfold.
Published A protein that enables smell--and stops cell death
(via sciencedaily.com) Original source While smell plays a considerable role in the social interactions of humans -- for instance, signaling fear or generating closeness -- for ants, it is vitally important. Researchers have found that a key protein named Orco, essential for the function of olfactory cells, is also critical for the cells' survival in ants.
Published Changes Upstream: RIPE team uses CRISPR/Cas9 to alter photosynthesis for the first time
(via sciencedaily.com) Original source Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, this study, is an unbiased gene-editing approach to increase gene expression and downstream photosynthetic activity. The approach is more difficult than transgenic breeding, but could potentially preempt regulatory issues by changing DNA already within the plant, allowing the plants to get in the hands of farmers sooner.
Published Fat molecule's inability to bond with shape-shifting protein in cell's powerhouse linked to an inherited metabolic disease
(via sciencedaily.com) Original source By studying mutations in yeast and human cells, scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.
Published Silkworms help grow better organ-like tissues in labs
(via sciencedaily.com) Original source Biomedical engineers have developed a silk-based, ultrathin membrane that can be used in organ-on-a-chip models to better mimic the natural environment of cells and tissues within the body. When used in a kidney organ-on-a-chip platform, the membrane helped tissues grow to recreate the functionality of both healthy and diseased kidneys.