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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Liquid droplets shape how cells respond to change      (via sciencedaily.com)     Original source 

New research has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of liquid droplets, leading to hyperactive signaling and tumor formation.

Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

AI can improve Alzheimer's treatment through the 'gut-brain axis'      (via sciencedaily.com)     Original source 

Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease. Previous studies showed that Alzheimer's disease patients have changes in their gut bacteria as the disease develops. The study outlines a computational method to determine how bacterial byproducts called metabolites interact with receptors on cells and contribute to Alzheimer's disease.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Scientists discover the cellular functions of a family of proteins integral to inflammatory diseases      (via sciencedaily.com)     Original source 

In a scientific breakthrough, researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Chemistry: Biochemistry Physics: Optics
Published

Switching off the light to see better      (via sciencedaily.com)     Original source 

Researchers used structured light and switchable fluorescent molecules to reduce the background light from the out-of-plane regions of microscope samples. This method allowed for the acquisition of images that surpassed the conventional resolution limit, and it may be useful for further study of cell clusters and other biological systems.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Protein network dynamics during cell division      (via sciencedaily.com)     Original source 

An international team has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Molecular
Published

Breakthrough rice bran nanoparticles show promise as affordable and targeted anticancer agent      (via sciencedaily.com)     Original source 

Plant-derived nanoparticles have demonstrated significant anticancer effects. Researchers recently developed rice bran-derived nanoparticles (rbNPs) that efficiently suppressed cell proliferation and induced programmed cell death of only cancer cells. Furthermore, rbNPs successfully suppressed the growth of tumors in mice having aggressive adenocarcinoma in their peritoneal cavity, without any adverse effects. Given their low production costs and high efficacy, rbNPs hold great promise for developing affordable and safe anticancer agents.

Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Zoology
Published

New compound from blessed thistle promotes functional nerve regeneration      (via sciencedaily.com)     Original source 

Blessed thistle (Cnicus benedictus) is a plant in the family Asteraceae. For centuries, it has been used as a medicinal herb as an extract or tea, e.g. to aid the digestive system. Researchers have now found a completely novel use for Cnicin. Animal models as well as human cells have shown that Cnicin significantly accelerates axon (nerve fibers) growth.

Environmental: Water Geoscience: Earth Science Geoscience: Geochemistry Geoscience: Geography Geoscience: Geology
Published

The Italian central Apennines as a source of CO2      (via sciencedaily.com)     Original source 

Tectonically active mountains play an important role in the natural CO2 regulation of the atmosphere. Competing processes take place here: At Earth's surface, erosion drives weathering processes that absorb or release CO2, depending on the type of rock. At depth, the heating and melting of carbonate rock leads to the outgassing of CO2 at the surface. In the central Italian Apennine Mountains, researchers have now investigated and balanced all of these processes in one region for the first time -- using, among others, analyses of the CO2 content in mountain rivers and springs.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology
Published

Key protein regulates immune response to viruses in mammal cells      (via sciencedaily.com)     Original source 

Researchers have revealed the regulatory mechanism of a specific protein, TRBP, that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and nucleic acid medicines to treat genetic disorders.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Light show in living cells      (via sciencedaily.com)     Original source 

Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge -- especially in living cells, as the required fluorescent labeling had to be individually attached to each protein. The research group has now overcome this hurdle: With a method called 'vpCells,' it is possible to label many proteins simultaneously, using five different fluorescent colors.

Geoscience: Earth Science Geoscience: Earthquakes Geoscience: Geology
Published

Scientists trigger mini-earthquakes in the lab      (via sciencedaily.com)     Original source 

Earthquakes and landslides are famously difficult to predict and prepare for. By studying a miniature version of the ground in the lab, scientists have demonstrated how these events can be triggered by a small external shock wave. Bring a flotation device: it involves the ground briefly turning into a liquid!

Environmental: General Environmental: Water Geoscience: Geography Geoscience: Geology Geoscience: Oceanography
Published

One third of China's urban population at risk of city sinking, new satellite data shows      (via sciencedaily.com)     Original source 

Land subsidence is overlooked as a hazard in cities, according to new research. Scientists used satellite data that accurately and consistently maps land movement across China.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Biology: Marine Biology: Microbiology Biology: Zoology Ecology: General Ecology: Nature Ecology: Research Ecology: Sea Life Environmental: Biodiversity Environmental: Ecosystems Environmental: General Geoscience: Environmental Issues Geoscience: Geography Geoscience: Oceanography
Published

Marine microbial populations: Potential sensors of the global change in the ocean      (via sciencedaily.com)     Original source 

Animal and plant populations have been extensively studied, which has helped to understand ecosystem processes and evolutionary adaptations. However, this has not been the case with microbial populations due to the impossibility of isolating, culturing and analyzing the genetic content of the different species and their individuals in the laboratory. Therefore, although it is known that populations of microorganisms include a great diversity, this remains largely uncharacterized.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Environmental: General
Published

RNA's hidden potential: New study unveils its role in early life and future bioengineering      (via sciencedaily.com)     Original source 

The origin of life continues to remain a matter of debate. The ribonucleic acid (RNA) world hypothesis proposes that 'ribozymes' which store genetic information and possess catalytic functions may have supported the activities of early life forms. Now, researchers explore how RNA elongation is regulated allosterically, shedding light on its impact on early life processes and offering insights into the fabrication of arbitrary RNA nanostructures with various modern applications.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics
Published

Calorie restriction study reveals complexities in how diet impacts aging      (via sciencedaily.com)     Original source 

The rate at which human cells age is influenced by multiple interconnected factors. New research examined how restricting calories influences telomere length and biological aging.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Tracking a protein's fleeting shape changes      (via sciencedaily.com)     Original source 

Researchers have developed a powerful, new technique to generate 'movies' of changing protein structures and speeds of up to 50 frames per second.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Researchers uncover human DNA repair by nuclear metamorphosis      (via sciencedaily.com)     Original source 

Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.

Biology: Biochemistry Biology: Biotechnology Biology: General Biology: Zoology Offbeat: General Offbeat: Plants and Animals
Published

Older males out-compete young males outside breeding pairs, bird study shows      (via sciencedaily.com)     Original source 

Young male blue tits are less successful in fathering offspring outside their breeding pair, not because of a lack of experience, but because they are outcompeted by older males, researchers report.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Microbiology
Published

How tardigrades can survive intense radiation      (via sciencedaily.com)     Original source 

Researchers have discovered that tardigrades -- microscopic animals famed for surviving harsh extremes -- have an unusual response to radiation.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Sea Life Geoscience: Geochemistry
Published

How blue-green algae manipulate microorganisms      (via sciencedaily.com)     Original source 

A research team discovers previously unknown gene that indirectly promotes photosynthesis Protein regulator NirP1 influences the coordination of the nitrogen and carbohydrate metabolism 'Such protein regulators could in future be deployed in 'green' and 'blue' biotechnology for targeted control of the metabolism,' says geneticist.