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Categories: Biology: Biotechnology, Geoscience: Oceanography

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Researchers have developed and demonstrated a new method for high-throughput single-cell sorting that uses stimulated Raman spectroscopy rather than the traditional approach of fluorescence-activated cell sorting. The new approach could offer a label-free, nondestructive way to sort cells for a variety of applications, including microbiology, cancer detection and cell therapy.

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The NSL (non-specific lethal) complex regulates thousands of genes in fruit flies and mammals. Silencing the NSL genes leads to the death of the organism, which gave the complex its curious name. Researchers have now discovered that the genes regulated by the NSL complex also include genes of the intraciliary transport system. This enables different cell types to form cilia on their surface, which are important for cell communication. The study shows that these genes are 'switched on' by the NSL complex, regardless of whether a particular cell has cilia or not. The researchers found that this class of cilia-associated genes is crucial for the function of podocytes. This is a highly specialized cell type of the kidney that, paradoxically, does not have cilia. These findings have important implications for ciliopathies and kidney disease.

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Researchers see potential in educational settings for the newest official ChatGPT plugin, called Code Interpreter, they've found limitations for its use by scientists who work with biological data utilizing computational methods to prioritize targeted treatment for cancer and genetic disorders.

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Scientific exploration of the deep ocean has largely remained inaccessible to most people because of barriers to access due to infrastructure, training, and physical ability requirements for at-sea oceanographic research.

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A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens. A new study sheds light on the mechanisms involved in the complex interplay between taste perception and immune function. Their work also highlights the potential of a sequencing tool for investigating epigenetic mechanisms that affect taste-cell gene expression.

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Researchers have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new ways for treating lung diseases, such as emphysema, pulmonary fibrosis and COVID-19. The two studies describe the methodologies for engineering lung stem cells and transplanting them into injured experimental lungs without immunosuppression.

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Researchers have discovered how proteins work in tandem to regulate 'treadmilling', a mechanism used by the network of microtubules inside cells to ensure proper cell division.

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Emperor penguin colonies experienced unprecedented breeding failure in a region of Antarctica where there was total sea ice loss in 2022. The discovery supports predictions that over 90% of emperor penguin colonies will be quasi-extinct by the end of the century, based on current global warming trends.

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Researchers used advanced technology to study a massive aggregation of deep-sea octopus gathered at thermal springs near an extinct underwater volcano off the coast of Central California. Warm water from hydrothermal springs accelerates development of octopus embryos, giving young octopus a better chance of survival. The Octopus Garden is the largest known aggregation of octopus on the planet -- the size of this nursery, and the abundance of other marine life that thrives in this rich community, highlight the need to understand and protect the hotspots of life on the deep seafloor from threats like climate change and seabed mining.

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In a groundbreaking endeavor, researchers have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse's lifespan. The research opens exciting possibilities for unlocking the secrets of aging and extending human lifespan.

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Geoscientists have created a new method that can reconstruct the drift path and origin of debris from flight MH370, an aircraft that went missing over the Indian Ocean in 2014 with 239 passengers and crew. 

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A discovery about how a common insect acquires a microbe that is essential for its growth may help in the control of an agricultural pest.

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Regulatory genes -- genes that control how other genes are used -- are responsible for 69% of the heritability of dairy cattle traits such as milk production and fertility, according to a new study. This contribution is 44% more than expected and much higher than previous studies of regulatory genes in humans. The findings, reported by a team of animal and human geneticists, could improve the efficiency of agricultural breeding programs. The study also helps solve the longstanding mystery of why mammalian genomes contain so much noncoding DNA.

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The entire contiguous U.S. has experienced massive urban expansions and the Atlantic Coast shows outstandingly high rates. Urban expansion has substantially squeezed the space of tidal flats and affected surrounding environments. In new urban areas, tidal flats have undergone considerable degeneration with more significant patterns as they get closer to new urban locations. Tidal flats protect against the ocean's destructive powers such as hurricanes. Without some inland spaces to move around, they will likely disappear, which will have dire consequences for beachfront communities.

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A new study shows that water underneath glaciers may surge due to thinning ice sheets -- a dangerous feedback cycle that could increase glacial melt, sea level rise, and biological disturbances.

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The in-depth analysis reveals how local tidal currents strongly affect the movement of sea ice in the Arctic ocean and provides an unprecedented look at how the makeup of the seafloor is causing some of the most abrupt changes.

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In the waters off the Hawaiian Islands, rates of calcification were measured in the deepest coral colonies.

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Tiny plastic particles can be found in the air over the oceans even far away from the coast. According to a new study, microplastics are not only carried by the wind, but also escape into the atmosphere from seawater. Researchers present data on the composition and sources of different types of plastic in the air over the North Atlantic and the origin of the particles.

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With methods of so-called geoengineering, the climate could theoretically be artificially influenced and cooled. Researchers have now investigated whether it would be possible to prevent the melting of the West Antarctic ice sheet by artificially 'dimming the sun'. The results show that artificial influence does not work without decarbonization and entails high risks.

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Microscopic plastic particles have been found in the fats and lungs of two-thirds of the marine mammals in a graduate student's study of ocean microplastics. The presence of polymer particles and fibers in these animals suggests that microplastics can travel out of the digestive tract and lodge in the tissues.