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Categories: Biology: Biotechnology, Geoscience: Oceanography

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Researchers describe how gut-on-a-chip devices can bridge lab models and human biology. Modeling the microbiome is particularly difficult because of its unique environmental conditions, but through creative design, gut-on-a-chip devices can simulate many of these properties, such as the gut's anaerobic atmosphere, fluid flow, and pulses of contraction/relaxation. Growing intestinal cells in this environment means that they more closely resemble human biology compared to standard laboratory cell cultures.

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What we think of as the classic West Coast climate began just about 4,000 years ago, finds a study on climate trends of the Holocene era.

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Previous research estimated that it took hundreds of million years for the ancient Earth's magma ocean to solidify, but new research narrows these large uncertainties down to less than just a couple of million years.

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Biochemists have succeeded in resurrecting the ancestral genes of five detoxifying enzymes which are present in all tetrapods to show how their divergence in function has occurred.

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By simulating early Earth conditions in the lab, researchers have found that without specific amino acids, ancient proteins would not have known how to evolve into everything alive on the planet today -- including plants, animals, and humans.

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Glaciers -- giant blocks of moving ice -- along Antarctica's coastline are flowing faster in the summer because of a combination of melting snow and warmer ocean waters, say researchers. On average, the glaciers travel at around one kilometre a year. But a new study has found a seasonal variation to the speed of the ice flow, which speeded up by up to 22 % in summer when temperatures are warmer. This gives an insight into the way climate change could affect the behaviour of glaciers and the role they could play in raising sea levels.

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Textbooks will tell you that in dividing cells, production of new DNA peaks during the S-phase, while production of other macromolecules, such as proteins, lipids, and polysaccharides, continues at more or less the same level. Molecular biologists have now discovered that this is not true: protein synthesis shows two peaks and lipid synthesis peaks once.

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Haematopoietic stem cell transplantation for the treatment of severe blood cancers is the only medical intervention that has cured two people living with HIV in the past. An international group of physicians and researchers has now identified another case in which HIV infection has been shown to be cured in the same way. The successful healing process of this third patient was for the first time characterized in great detail virologically and immunologically over a time span of ten years.

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Influenza viruses are becoming increasingly resilient to medicines. For this reason, new active ingredients are needed. Important findings in this regard have been provided: for the virus to proliferate, the polymerase of the influenza A virus has to be modified many times through enzymes in the host cells. The team of researchers was able to produce a comprehensive map of types of modification. Medicines directed against the enzymes woud be resilient to rapid mutations in the virus, thus offering great potential for the future.

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By exploring the stability and collapse of marine ecosystems during the Permian-Triassic mass extinction, researchers gain insights into modern biodiversity crisis.

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Researchers believe rising sea temperatures are to blame for the plummeting number of invertebrates such as molluscs and sea urchins at Rottnest Island off Western Australia, with some species having declined by up to 90 per cent between 2007 and 2021.

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A team has developed a method for selectively manipulating genetically engineered cells with ultrasound.

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Researchers have provided the first experimental evidence that a species of endangered sea star protects kelp forests along North America's Pacific Coast by preying on substantial numbers of kelp-eating urchins.

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As sea ice declines in the Arctic, bowhead whales are staying north of the Bering Strait more frequently, a shift that could affect the long-term health of the bowhead population and impact the Indigenous communities that rely on the whales, a new study shows.

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The trawling of thousands of satellite measurements using artificial intelligence has shown researchers that meltwater in tunnels beneath Greenland's ice sheet causes it to change speed, and in some places, accelerate greatly towards the ocean. This can increase melting, especially in a warming climate, which is why the study's researchers think that it is important to keep an eye on.

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Not all Chinook salmon are created equal, and this has a major impact on the energetics for southern resident killer whales. A recent study quantified the lipid content in Fraser River Chinook salmon -- the southern resident's preferred meal -- and found that spring-run Chinook salmon, the earliest to arrive to the Salish Sea are lipid-rich and energy dense; a critical factor for the killer whales who prey on them. Fraser River Chinook salmon that come later in the season have lower energy density.

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Researchers have identified 26 global warming accelerators known as amplifying feedback loops that the researchers say aren't being properly included in climate models. They note that the findings add urgency to the need to respond to the climate crisis and provide a roadmap for policymakers aiming to avert the most severe consequences of a warming planet.

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56 million years ago, the Earth experienced one of the largest and most rapid climate warming events in its history: the Paleocene-Eocene Thermal Maximum (PETM), which has similarities to current and future warming. This episode saw global temperatures rise by 5-8°C. It was marked by an increase in the seasonality of rainfalls, which led to the movement of large quantities of clay into the ocean, making it uninhabitable for certain living species. This scenario could be repeated today.

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Seabed mining could soon begin in the deep ocean -- but the potential impact on animals including whales is unknown, researchers have warned.

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A study shows that an irreversible loss of the ice sheets, and a corresponding acceleration of sea level rise, may be imminent if global temperature cannot be stabilized below 1.8 degrees Celsius.