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Categories: Biology: Biotechnology, Geoscience: Oceanography
Published New method to help with analysis of single cell data
(via sciencedaily.com) Original source CITE-seq (cellular indexing of transcriptomes and epitopes) is an RNA sequencing-based method that simultaneously quantifies cell surface protein and transcriptomic data within a single cell readout. The ability to study cells concurrently offers unprecedented insights into new cell types, disease states or other conditions. While CITE-seq solves the problem of detecting a limited number of proteins while using single-cell sequencing in an unbiased way, one of its limitations is the high levels of background noise that can hinder analysis.
Published Heat tolerant coral may trade fast growth for resilience
(via sciencedaily.com) Original source Algae living within the soft tissue of coral supply much of the energy needed by their hosts, and some symbiotic algae help coral withstand warmer water better than others. Researchers have now found that there was a tradeoff for corals dominated by the thermally sensitive algae -- they have higher growth, but only in cooler water.
Published Rediscovery of rare marine amoeba Rhabdamoeba marina
(via sciencedaily.com) Original source Researchers have rediscovered and successfully cultivating Rhabdamoeba marina -- a rare marine amoeba that has only been reported in two cases in the past century. Using this culture strain, they performed a comprehensive analysis of its genetic sequence, revealing for the first time the phylogenetic position of this enigmatic amoeba, and proposed a novel taxonomic classification based on their research findings.
Published Research in Lake Superior reveals how sulfur might have cycled in Earth's ancient oceans
(via sciencedaily.com) Original source A scientists has sulfur on her mind. The yellow element is a vital macronutrient, and she's trying to understand how it cycles through the environment. Specifically, she's curious about the sulfur cycle in Earth's ancient ocean, some 3 billion years ago.
Published Genomic tug of war could boost cancer therapy
(via sciencedaily.com) Original source Researchers have discovered a 'genomic tug of war' in animal studies that could influence how well certain patients -- or certain cancers -- respond to decitabine, a drug used to treat myelodysplastic syndromes that is plagued by drug resistance issues. For the first time, researchers show that decitabine causes coding and non-coding regions of DNA to engage in a tug of war for a gene activator, called H2A.Z. Typically, deticabine draws this gene activator away from coding DNA, causing gene expression to grind to a halt and cells to die. However, many types of cancer have very high levels of H2A.Z, which may help them overcome this decitabine-induced tug of war, allowing the cancer to grow.
Published How cell identity is preserved when cells divide
(via sciencedaily.com) Original source A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation. Within each cell's nucleus, researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications.
Published Much more than waste: Tiny vesicles exchange genetic information between cells in the sea
(via sciencedaily.com) Original source Researchers take a look at data that has so far been mostly discarded as contamination, revealing the previously underestimated role of extracellular vesicles (EVs). These are important for the exchange of genetic information between cells and thus for the microbial community in the sea.
Published More than meows: How bacteria help cats communicate
(via sciencedaily.com) Original source Many mammals, from domestic cats and dogs to giant pandas, use scent to communicate with each other. A new study shows how domestic cats send signals to each other using odors derived from families of bacteria living in their anal glands.
Published Climate change effects hit marine ecosystems in multiple waves, according to marine ecologists
(via sciencedaily.com) Original source A new approach to examining the effects of climate change on marine ecosystems may provide a more accurate understanding of climate change responses -- and predictions for future consequences -- according to a new article. The paper highlights the interplay between the trend of climate warming and the fluctuations in local temperature. These two properties cause atypically warm events such as marine heatwaves to occur with increasing frequency and magnitude.
Published Ice cores from Earth's highest tropical peak provide insight into climate variability
(via sciencedaily.com) Original source A new study examines ice cores from the summit of the highest tropical mountain in the world, and finds unique insight into the climate record of the Amazon Basin over the last six decades.
Published How bacteria recognize viral invasion and activate immune defenses
(via sciencedaily.com) Original source Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.
Published Visualizing 'traffic jams' inside living cells
(via sciencedaily.com) Original source Researchers have unveiled a groundbreaking approach to label-free visualization of intracellular cargo trafficking in living cells, achieving high-speed and limitless observation capabilities. By developing a cargo-localization interferometric scattering (CL-iSCAT) microscope, scientists meticulously tracked the intricate movements of numerous cargos in the bustling cellular world. Surprisingly, cells employ human-like strategies to manage their transport challenges.
Published Colliding ribosomes activate RNA repair
(via sciencedaily.com) Original source Researchers discover how ribosomes contribute to the recognition and removal of RNA crosslinking damage.
Published Climate engineering could slow Antarctic ice loss, study suggests
(via sciencedaily.com) Original source A study reports that scattering sunlight-reflecting particles in the atmosphere -- a theoretical form of climate engineering known as 'stratospheric aerosol injection' -- has potential to slow rapid ice melt in Western Antarctica.
Published Novel C. diff structures are required for infection, offer new therapeutic targets
(via sciencedaily.com) Original source Newly discovered iron storage 'ferrosomes' inside the bacterium C. diff -- the leading cause of hospital-acquired infections -- are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do not contain organelles.
Published Roaming seabirds need ocean-wide protection
(via sciencedaily.com) Original source Seabirds roam far and wide in the Indian Ocean -- so they need ocean-wide protection, new research shows.
Published Previously unknown luminescence revealed in ten deep sea species and an order of sea cucumbers
(via sciencedaily.com) Original source Researchers present evidence of previously unknown luminosity in 10 deep-sea species, suggesting underestimated diversity. These new discoveries include a member of the order Molpadia, which was previously thought not to be luminescent. The authors stress the importance of considering the ecological role of bioluminesence and the need for conservation.
Published Melting ice falling snow: Sea ice declines enhance snowfall over West Antarctica
(via sciencedaily.com) Original source As the world continues to warm, Antarctica is losing ice at an increasing pace, but the loss of sea ice may lead to more snowfall over the ice sheets, partially offsetting contributions to sea level rise.
Published Shedding new light on sugars, the 'dark matter' of cellular biology
(via sciencedaily.com) Original source Chemists have developed a new tool for detecting interactions between sugars and lectins, a discovery that could help in the fight against diseases like cancer.
Published Study sheds light on how Earth cycles fossil-carbon
(via sciencedaily.com) Original source Researches used rhenium as a proxy for fossil carbon in order to quantify the rate at which Earth naturally releases carbon dioxide into the atmosphere and found that high rates of carbon breakdown persist across the different geographical profiles of a river basin.