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Categories: Anthropology: General, Biology: Biotechnology

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The largest-yet analysis of ancient DNA in Africa, which includes the first ancient DNA recovered from members of the medieval Swahili civilization, has now broken the stalemate about the extent to which people from outside Africa contributed to Swahili culture and ancestry.

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Traces of ancient empires that stretched across Africa remain in the DNA of people living on the continent, reveals a new genetics study.

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Scientists often look to the past for clues about how Earth's landscapes might shift under a changing climate, and for insight into the migrations of human communities through time. A new study offers both by providing, for the first time, a reconstruction of prehistoric temperatures for some of the first known North American settlements.

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Researchers have developed a method to measure coral biodiversity through extracting the environmental DNA (or eDNA) from a liter of surface seawater collected from above a reef. The method has been confirmed to work through observations made by scientific divers in the same areas of ocean. This has paved the way for large-scale comprehensive surveys of reef-building coral to take place and removes the reliance of direct observations made through scientific scuba diving or snorkeling.

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Naloxone -- a fast-acting opioid antidote -- has saved lives, but it's less effective against powerful synthetic opioids, such as fentanyl. In an interesting twist, researchers are now investigating cannabidiol (CBD), a component of marijuana, as a possible alternative to the popular antidote. Today, a team reports compounds based on CBD that reduce fentanyl binding and boost the effects of naloxone.

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Researchers discover that actin acts in the cell nucleus and is partly responsible for the expression of male sexual characteristics.

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Free-range organic chicken or factory farming? Scientists have developed a new detection method that can reveal such differences in husbandry. The so-called epigenetic method is based on the analysis of the characteristic patterns of chemical markers on the genome of the animals.

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With CRISPR-Cas9 technology, humans can now rapidly change the evolutionary course of animals or plants by inserting genes that can easily spread through entire populations. An evolutionary geneticist proposes that we call this evolutionary meddling 'genetic welding.' He argues that we must scientifically and ethically scrutinize the potential consequences of genetic welding before we put it into practice.

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A team of scientists designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

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To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code. Now, in a study using blood samples from men and women with HIV on long-term suppressive therapy, a team of scientists reports new evidence that one such stable reservoir of HIV genomes can be found in circulating white blood cells called monocytes.

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Squids and octopuses are masters of camouflage. But some aspects of how they become reversibly transparent are still 'unclear,' because researchers can't culture cephalopod skin cells in the lab. Now, researchers have replicated the tunable transparency of squid skin in mammalian cells, which are more easily cultured.

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Researchers have developed a hybrid micro-robot, the size of a single biological cell (about 10 microns across), that can be controlled and navigated using two different mechanisms -- electric and magnetic. The micro-robot is able to navigate between different cells in a biological sample, distinguish between different types of cells, identify whether they are healthy or dying, and then transport the desired cell for further study, such as genetic analysis.

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A parasite which has devastating impacts on agriculture and human health is the first pathogen to have its proteins located and mapped within its cells -- providing clues to their function and helping to identify potential drug targets.

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Researchers have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB. If this natural process can be harnessed with new treatments, it could present an alternative to, or improve use of antibiotics, especially where bacteria have become resistant to existing drugs.

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Damage in the human genome can be repaired. But this works better in germ cells, sperm and eggs, than in normal body cells. Responsible for this is the DREAM protein complex, which prevents the activation of all available repair mechanisms. A research team has now shown that normal body cells can also be repaired better once this complex has been deactivated. In the long run, the scientists hope to develop better therapies to prevent cancer and aging-associated diseases.

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Scientists have significantly advanced the race to control plant responses to temperature on a rapidly warming planet. Key to this breakthrough is miRNA, a molecule nearly 200,000 times smaller than the width of a human hair.

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Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. Researchers have now described a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans. These effector memory B cells appear to be poised for a rapid serum antibody response upon secondary challenge one year later.

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Researchers find stem cells use a surprising system for discarding misfolded proteins. This unique pathway could be the key to maintaining long-term health and preventing age-related blood and immune disorders.

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Future ocean warming and marine heatwaves could impact the growth and development of clownfish during their earliest life stages, suggests a new study.

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Natural and engineered versions of tardigrade proteins can be used to stabilize an important pharmaceutical used to treat people with hemophilia and other conditions without the need for refrigeration -- even amid high temperatures and other difficult conditions.