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Categories: Anthropology: General, Biology: Biotechnology

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Organoids help researchers understand biological processes in health and in disease. It is, however, difficult to influence the way in which they organize themselves into complex tissues. Now a group has found a new way to do so.

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Researchers have uncovered that proteins use a common chemical label as a shield to protect them from degradation, which in turn affects motility and aging.

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Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems. For a long time, a certain type of fossil lipid, so-called 2-methylhopanes, was considered to be an important biomarker for Cyanobacteria in sediments, some of which are hundreds of millions of years old. However, this came into doubt when it turned out that not only Cyanobacteria but also Alphaproteobacteria are genetically capable of producing these lipids.

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Bacteriophages, also called phages, are viruses that infect and kill bacteria, their natural hosts. But from a macromolecular viewpoint, phages can be viewed as nutritionally enriched packets of nucleotides wrapped in an amino acid shell. A study suggests that mammalian cells internalize phages as a resource to promote cellular growth and survival.

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Researchers have made a significant discovery by identifying and characterizing three novel species within the Minorisa genus of marine picoplankton. Before this study, only one species of Minorisa was recognized. This finding reveals previously unseen diversity of Minorisa, thereby enhancing species identification and our understanding of its ecological functions in marine ecosystems.  

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Ancient people immigrated to Cancun Island and were treated just like locals, according to a new study.

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Human populations in Neolithic Europe fluctuated with changing climates, according to a new study.

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A team of researchers has gained new insights into the respiratory system of fruit flies -- the so-called tracheal system -- which could be important for future research into aneurysms. Scientists carried out genetic, cell biological and biochemical studies on Drosophila embryos. They found that the cells in the fruit fly's tracheal system are connected to the extracellular matrix by the proteins Dumpy and Piopio.

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Opening a clamshell of berries and seeing them coated in fuzzy mold is a downer. And it's no small problem. Gray mold and other fungi, which cause fruit to rot, lead to significant economic losses and food waste. Now, researchers report that compounds from sunflower crop waste prevented rotting in blueberries. They suggest the food industry could use these natural compounds to protect against post-harvest diseases.

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New research reveals how the bacteria strain Wolbachia pipientis enhances the fertility of the insects it infects, an insight that could help scientists increase the populations of mosquitoes that do not carry human disease.

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Scientists studied the genomes of 30 kingfisher species to try to identify the genes that allow kingfishers to dive headfirst into water without huring their brains. The researchers found that the diving birds have unusual mutations to the genes that produce tau: a protein that helps stabilize tiny structures in the brain, but which can build up in humans with traumatic brain injuries or Alzheimer's disease. The researchers suspect that these variations in the kingfishers' tau proteins might protect their brains when they dive.

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Primatologists are using genetic analysis to determine the geographic origin of ancient mummified baboons found in Egypt. The team finds evidence that the two legendary trading regions of Punt and Adulis may have been the same place separated by a thousand years of history.

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Newly published research proves that it's possible to treat high blood pressure by using specially engineered Lactobacillus paracasei to produce a protein called ACE2 in the gut, reducing gut angiotensin II and, in turn, lowering blood pressure. The study, done in lab rats that are predisposed to hypertension and unable to naturally produce ACE2, opens new doors in the pursuit of harnessing our body's own microbiome to regulate blood pressure.

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A team of researchers has developed a software tool that provides a way for the safer design of genome editing in all organisms with a transcriptome. For about a decade, researchers have used the CRISPR technology for genome editing. However, there are some challenges in the use of CRISPR. The new analysis system overcomes these challenges and allows researchers to perform safer on- and off-target assessments without a reference genome. It holds the potential for applications in medicine, agriculture, and biological research.

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Anthropologists challenge the traditional view of men as hunters and women as gatherers in prehistoric times. Their research reveals evidence of gender equality in roles and suggests that women were physically capable of hunting. The study sheds light on the gender bias in past research and calls for a more nuanced understanding of prehistoric gender roles.

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Researchers looking to develop a long-acting, injectable malaria preventive using atovaquone have shown in a new study that resistance may not be the challenge scientists thought it was, particularly when using atovaquone as a malaria preventive. Malaria parasites in infected patients being treated with atovaquone tend to develop a resistance to the drug. Because of this, atovaquone by itself is not used as a malaria treatment nor has not been seen as a strong candidate for use as a preventive. 

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Researchers have found a gene associated with longevity in golden retrievers, one of the most popular breeds of dogs.

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University and federal scientists used genetic sleuthing to study how salmon were affected by two major culvert replacements near the city of Bellingham. One project, a major upgrade under Interstate-5, had a big impact, while the other old culvert may have been less of a barrier to fish. Authors from the UW and NOAA are studying the use of environmental DNA, or eDNA, in future environmental impact reporting.

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A plant geneticist and computational biologist teamed up to decipher the unpredictability of natural and engineered mutations in tomatoes. They discovered some combinations of mutations behave as expected while others are more erratic. Their work may help scientists find some order in the chaos of evolution and genome editing.

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Bats may have lived in caves and used soundwaves to navigate much earlier than first thought.