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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Tiny worm, giant leap: Discovery of highly specific fatty acid attachment to proteins      (via sciencedaily.com)     Original source 

In a world where the intricacies of molecular biology often seem as vast and mysterious as the cosmos, a new groundbreaking study delves into the microscopic universe of proteins, unveiling a fascinating aspect of their existence. This revelation could hold profound implications for the understanding and treatment of a myriad of human diseases.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Biology: Molecular Environmental: General Geoscience: Geochemistry
Published

Don't overeat: How archaea toggle the nitrogen-uptake switch      (via sciencedaily.com)     Original source 

By tightly regulating nitrogen uptake, microorganisms avoid overeating nitrogen and thus wasting energy. Scientists now reveal how some methanogenic archaea manage to do so.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

DNA construction led to unexpected discovery of important cell function      (via sciencedaily.com)     Original source 

Researchers have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new avenues for understanding how the Notch signalling pathway works and how it is involved in several serious diseases.

Anthropology: General Archaeology: General Offbeat: General Offbeat: Paleontology and Archeology
Published

Despite intensive scientific analyses, this centaur head remains a mystery      (via sciencedaily.com)     Original source 

For almost 200 years, archaeologists have been puzzled by a mysterious brown stain on the ancient Greek Parthenon temple in Greece. Now, researchers have conducted new scientific analyses, and their verdict is clear: The mystery remains.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Offbeat: General Offbeat: Plants and Animals
Published

Ancient 'chewing gum' reveals stone age diet      (via sciencedaily.com)     Original source 

What did people eat on the west coast of Scandinavia 10,000 years ago? A new study of the DNA in a chewing gum shows that deer, trout and hazelnuts were on the diet. It also shows that one of the individuals had severe problems with her teeth.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Endangered Species
Published

Nearly dead plants brought back to life: Keys to aging hidden in the leaves      (via sciencedaily.com)     Original source 

Scientists have known about a particular organelle in plant cells for over a century. However, scientists have only now discovered that organelle's key role in aging.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Study throws our understanding of gene regulation for a loop      (via sciencedaily.com)     Original source 

To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Machine learning reveals sources of heterogeneity among cells in our bodies      (via sciencedaily.com)     Original source 

A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry Physics: Optics
Published

Glowing COVID-19 diagnostic test prototype produces results in one minute      (via sciencedaily.com)     Original source 

Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.

Archaeology: General Environmental: Ecosystems Environmental: Water Geoscience: Earth Science Geoscience: Environmental Issues Paleontology: Climate
Published

Stalagmites as climate archive      (via sciencedaily.com)     Original source 

When combined with data from tree-ring records, stalagmites can open up a unique archive to study natural climate fluctuations, a research team has demonstrated. The researchers analyzed the isotopic composition of oxygen in a stalagmite formed from calcareous water in a cave in southern Germany. In conjunction with the data acquired from tree rings, they were able to reconstruct short-term climate fluctuations over centuries and correlate them with historically documented environmental events.

Anthropology: Cultures Anthropology: General Archaeology: General Biology: Biochemistry Paleontology: Early Mammals and Birds Paleontology: Fossils Paleontology: General
Published

Woolly mammoth movements tied to earliest Alaska hunting camps      (via sciencedaily.com)     Original source 

Researchers have linked the travels of a 14,000-year-old woolly mammoth with the oldest known human settlements in Alaska, providing clues about the relationship between the iconic species and some of the earliest people to travel across the Bering Land Bridge. Isotopic data, along with DNA from other mammoths at the site and archaeological evidence, indicates that early Alaskans likely structured their settlements to overlap with areas where mammoths congregated. Those findings, highlighted in the new issue of the journal Science Advances, provide evidence that mammoths and early hunter-gatherers shared habitat in the region. The long-term predictable presence of woolly mammoths would have attracted humans to the area.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Biology: Molecular Chemistry: Biochemistry
Published

Unraveling the role of supersulfides in regulating mitochondrial function and longevity      (via sciencedaily.com)     Original source 

Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.

Archaeology: General Biology: Biochemistry Biology: General Biology: Marine Ecology: Nature Ecology: Sea Life Paleontology: Climate Paleontology: Fossils Paleontology: General
Published

Key moment in the evolution of life on Earth captured in fossils      (via sciencedaily.com)     Original source 

New research has precisely dated some of the oldest fossils of complex multicellular life in the world, helping to track a pivotal moment in the history of Earth when the seas began teeming with new lifeforms -- after four billion years of containing only single-celled microbes.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Bioinformatics: Researchers develop a new machine learning approach      (via sciencedaily.com)     Original source 

To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

A novel pathway regulating lipid biosynthesis by fatty acids      (via sciencedaily.com)     Original source 

Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Molecular Chemistry: Biochemistry
Published

3D in vitro human atherosclerosis model for high-throughput drug screening      (via sciencedaily.com)     Original source 

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging      (via sciencedaily.com)     Original source 

Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Ecology: Endangered Species
Published

New rice lines for Africa offer virus protection      (via sciencedaily.com)     Original source 

The so-called Rice Yellow Mottle Virus (for short: RYMV) is responsible for high crop losses in Africa, particularly among small-scale farmers. A research team has now produced rice lines that are resistant to the disease by means of genome editing. The rice varieties are a preliminary step toward being able to generate resistant locally adapted elite varieties for small-scale food producers in Africa.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Chemistry: Biochemistry Chemistry: General Chemistry: Organic Chemistry Chemistry: Thermodynamics
Published

Spying on a shape-shifting protein      (via sciencedaily.com)     Original source 

Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases.

Archaeology: General Biology: Biochemistry Biology: Evolutionary Biology: General Biology: Zoology Ecology: Animals Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: Early Mammals and Birds Paleontology: Fossils Paleontology: General
Published

Oldest known fossilized skin is 21 million years older than previous examples      (via sciencedaily.com)     Original source 

Researchers have identified a 3D fragment of fossilized skin that is at least 21 million years than previously described skin fossils. The skin, which belonged to an early species of Paleozoic reptile, has a pebbled surface and most closely resembles crocodile skin. It's the oldest example of preserved epidermis, the outermost layer of skin in terrestrial reptiles, birds, and mammals, which was an important evolutionary adaptation in the transition to life on land.