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Categories: Biology: Biotechnology, Paleontology: General

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Biology: Evolutionary Biology: General Biology: Zoology Ecology: Extinction Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: Fossils Paleontology: General
Published

Tanks of the Triassic: New crocodile ancestor identified      (via sciencedaily.com)     Original source 

Dinosaurs get all the glory. But aetosaurs, a heavily armored cousin of modern crocodiles, ruled the world before dinosaurs did. These tanks of the Triassic came in a variety of shapes and sizes before going extinct around 200 million years ago. Today, their fossils are found on every continent except Antarctica and Australia.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Offbeat: General Offbeat: Plants and Animals
Published

Genetic basis for the evolution of hair discovered in the clawed frog      (via sciencedaily.com)     Original source 

The development of hair was of central importance for the evolution of mammals and thus also of humans. However, the evolutionary origin of the genetic program of hair was previously unknown. Researchers have now been able to show that important hair components and their genetic control have already evolved in amphibians. Human hair therefore shows unexpected similarities to the claws of clawed frogs.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Molecular
Published

How cells are ahead of the curve      (via sciencedaily.com)     Original source 

The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model predicting cellular behavior. Such universal principles now allow a better understanding of the migration of immune and cancer cells, paving the way for new treatment options.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Engineers measure pH in cell condensates      (via sciencedaily.com)     Original source 

In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured and compared with the pH of nearby non-nucleolar condensates including nuclear speckles and Cajal bodies.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Chemistry: Biochemistry Engineering: Nanotechnology Offbeat: General Offbeat: Plants and Animals
Published

DNA origami-based vaccines toward safe and highly-effective precision cancer immunotherapy      (via sciencedaily.com)     Original source 

Researchers have created a DNA origami platform called DoriVac, whose core component is a self-assembling square block-shaped nanostructure. DoriVac vaccines enabled tumor-bearing mice to better control the growth of tumors and to survive significantly longer than control mice.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Chemistry: Biochemistry Chemistry: Organic Chemistry Energy: Technology
Published

Breakthrough could make automated dosing systems universal      (via sciencedaily.com)     Original source 

Automated insulin dosing systems combine low-cost blood-glucose monitors with insulin pumps that use precision dosing to continuously regulate blood-sugar and hold it steady. Synthetic biologists have found a way to piggyback on the technology and make it universally applicable for the precision dosing of virtually any drug.

Biology: Biochemistry Biology: Biotechnology Biology: Developmental Biology: Evolutionary Biology: General Biology: Microbiology
Published

New study on mating behaviors offers clues into the evolution of attraction      (via sciencedaily.com)     Original source 

In examining the mating rituals of roundworms, researchers uncovered a unique approach to reproduction that maximizes genetic fitness.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Environmental: General Geoscience: Geochemistry Offbeat: Earth and Climate Offbeat: General Offbeat: Plants and Animals
Published

It's hearty, it's meaty, it's mold      (via sciencedaily.com)     Original source 

Scientists are exploring how tuning the genomes of mushrooms and molds can transform these food sources into gourmet, nutrient-packed meals made with minimal processing and a light environmental footprint.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Biology: Molecular
Published

Alzheimer's drug fermented with help from AI and bacteria moves closer to reality      (via sciencedaily.com)     Original source 

Researchers combined artificial intelligence and chemical biosensors to ferment the precursor of an Alzheimer's drug in bacteria.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

New bioengineered protein design shows promise in fighting COVID-19      (via sciencedaily.com)     Original source 

A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus responsible for COVID-19. The study focuses on the design and development of a novel protein capable of binding to the spike proteins found on the surface of the coronavirus. The goal behind this innovative approach is twofold: first, to identify and recognize the virus for diagnostic purposes, and second, to hinder its ability to infect human cells.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Even cells know the importance of recycling      (via sciencedaily.com)     Original source 

Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide a contact site for another protein, Tank-binding kinase 1 (TBK1), during this process. The OPTN-TBK1 relationship is necessary for these mitochondria to be recognized and eliminated from the cell. This mechanism may have relevance for developing drugs to treat Parkinson's disease.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Chemistry: Biochemistry Chemistry: Organic Chemistry Engineering: Biometric
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New simpler and cost-effective forensics test helps identify touch DNA      (via sciencedaily.com)     Original source 

Research has found a less expensive and easier to use test to learn more about forensic touch DNA. This research has important implications for forensic investigations and being able to identify DNA from a primary contact -- someone who may have committed the crime -- as well as secondary DNA that was inadvertently and indirectly transferred through touch.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology
Published

Steroid drugs used for HRT can combat E. coli and MRSA      (via sciencedaily.com)     Original source 

Researchers have combined computational and microbiology laboratory approaches to identify existing drugs that can be repurposed to combat antibiotic-resistant bacterial infections. This research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

New computational strategy boosts the ability of drug designers to target proteins inside the membrane      (via sciencedaily.com)     Original source 

Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Ecology: Endangered Species
Published

Simple trick could improve accuracy of plant genetics research      (via sciencedaily.com)     Original source 

Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables -- such as temperature -- affect gene activity in plants.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Milk to the rescue for diabetics? Cow produces human insulin in milk      (via sciencedaily.com)     Original source 

An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.

Biology: Botany Biology: Marine Biology: Zoology Paleontology: Dinosaurs Paleontology: Early Mammals and Birds Paleontology: Fossils Paleontology: General
Published

Alaska dinosaur tracks reveal a lush, wet environment      (via sciencedaily.com)     Original source 

A large find of dinosaur tracks and fossilized plants and tree stumps in far northwestern Alaska provides new information about the climate and movement of animals near the time when they began traveling between the Asian and North American continents roughly 100 million years ago.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: General Chemistry: Organic Chemistry
Published

A simple and robust experimental process for protein engineering      (via sciencedaily.com)     Original source 

A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

How a natural compound from sea squirts combats cancer      (via sciencedaily.com)     Original source 

Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.