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Categories: Biology: Biotechnology, Paleontology: Fossils
Published Colorado's spicy ancient history of chili peppers



Recently identified chili pepper fossils from Boulder and Denver museums challenge millions of years of global tomato evolutionary history. Now, that's some spicy science!
Published 360-million-year-old Irish fossil provides oldest evidence of plant self-defense in wood



Scientists have discovered the oldest evidence of plant self-defense in wood in a 360-million-year-old fossil from south-eastern Ireland. Plants can protect their wood from infection and water loss by forming special structures called 'tyloses'. These prevent bacterial and fungal pathogens from getting into the heartwood of living trees and damaging it. However, it was not previously known how early in the evolution of plants woody species became capable of forming such defenses. Published today in Nature Plants is the oldest evidence of tylosis formation from Late Devonian (360-million-year-old) fossil wood from the Hook Head Peninsula area, Co. Wexford, Ireland.
Published Researchers reveal a map to study novel form of cell-to-cell communication



An international team of researchers lays the foundation to examine how extracellular RNA and its carrier proteins found in bodily fluids function in a healthy as well as a diseased setting, potentially providing a means to accurately implement early detection and monitor disease processes.
Published Synthetic biology meets fashion in engineered silk



Engineers developed a method to create synthetic spider silk at high yields while retaining strength and toughness using mussel foot proteins.
Published Reinforcement learning: From board games to protein design



An AI strategy proven adept at board games like Chess and Go, reinforcement learning, has now been adapted for a powerful protein design program. The results show that reinforcement learning can do more than master board games. When trained to solve long-standing puzzles in protein science, the software excelled at creating useful molecules. In one experiment, proteins made with the new approach were found to be more effective at generating useful antibodies in mice than were previous methods. If this method is applied to the right research problems, it likely could accelerate progress in a variety of scientific fields.
Published Fungal genetics could help develop novel biotechnologies



An essential pillar of Earth's ecological system, fungi have long been used to better the lives of humans. While these organisms are still vastly understudied, a new review paper suggests that their unique genomes could be used to make progress in the biotech industry.
Published Engineering the next generation of cell and gene therapies



Investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.
Published Simple addition to corn bran could boost grain's nutritional value 15-35%



What if, by adding a couple of cell layers inside a corn kernel, the grain could become significantly richer in essential nutrients like iron, zinc, and protein? Such an improvement could benefit people who rely on corn for a large portion of their diet, as in many parts of the global south.
Published Study links 'stuck' stem cells to hair turning gray



Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.
Published Loops, flags and tension in DNA



Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they have visualized this.
Published New mechanism for DNA folding



A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.
Published X-ray analysis sheds new light on prehistoric predator's last meal



We now know more about the diet of a prehistoric creature that grew up to two and a half meters long and lived in Australian waters during the time of the dinosaurs, thanks to the power of x-rays. Researchers used micro-CT scans to peer inside the fossilized stomach remains of a small marine reptile -- a plesiosaur nicknamed 'Eric' after a song from the comedy group Monty Python -- to determine what the creature ate in the lead up to its death.
Published Novel nanocages for delivery of small interfering RNAs



Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation between the Universities of Amsterdam and Leiden, researchers have developed dedicated molecular nanocages for siRNA delivery. In a paper just out in the Journal Chem they present nanocages that are easy to prepare and display tuneable siRNA delivery characteristics.
Published Fluorescent blue coumarins in a folk-medicine plant could help us see inside cells



Plants that glow under ultraviolet (UV) light aren't only a figment of science fiction TV and movies. Roots of a traditional medicine plant called the orange climber, or Toddalia asiatica, can fluoresce an ethereal blue hue. And now, researchers have identified two coumarin molecules that could be responsible. These natural coumarins have unique fluorescent properties, and one of the compounds could someday be used for medical imaging.
Published SpyLigation uses light to switch on proteins



Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail. This technology has potential uses in tissue engineering, regenerative medicine, and understanding how the body works. The scientists applied their new method to control the glow of a green fluorescent protein derived from Japanese eel muscle.
Published Nullarbor rocks reveal Australia's transformation from lush to dust



Researchers have discovered how long ago the Australian Nullarbor plain dried out, with a new approach shedding light on how ancient climate change altered some of the driest regions of our planet.
Published Fossils reveal the long-term relationship between feathered dinosaurs and feather-feeding beetles



New fossils in amber have revealed that beetles fed on the feathers of dinosaurs about 105 million years ago, showing a symbiotic relationship of one-sided or mutual benefit.
Published New details of Tully monster revealed



For more than half a century, the Tully monster (Tullimonstrum gregarium), an enigmatic animal that lived about 300 million years ago, has confounded paleontologists, with its strange anatomy making it difficult to classify. Recently, a group of researchers proposed a hypothesis that Tullimonstrum was a vertebrate similar to cyclostomes (jawless fish like lamprey and hagfish). If it was, then the Tully monster would potentially fill a gap in the evolutionary history of early vertebrates. Studies so far have both supported and rejected this hypothesis. Now, using 3D imaging technology, a team in Japan believes it has found the answer after uncovering detailed characteristics of the Tully monster which strongly suggest that it was not a vertebrate. However, its exact classification and what type of invertebrate it was is still to be decided.
Published New genetic target for male contraception identified



Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals. Researchers identified expression of the gene, Arrdc5, in the testicular tissue of mice, pigs, cattle and humans. When they knocked out the gene in mice, it created infertility only in the males, impacting their sperm count, movement and shape.
Published How can a pollinating insect be recognized in the fossil record?



Insect pollination is a decisive process for the survival and evolution of angiosperm (flowering) plants and, to a lesser extent, gymnosperms (without visible flower or fruit). There is a growing interest in studies on the origins of the relationship between insects and plants, especially in the current context of the progressive decline of pollinating insects on a global scale and its impact on food production. Pollinating insects can be recognized in the fossil record, although to date, there has been no protocol for their differentiation. Fossil pollinators have been found in both rock and amber deposits, and it is in rock deposits that the first evidence of plant pollination by insects is being studied across the globe. But how can we determine which was a true insect pollinator in the past?