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Categories: Biology: Biotechnology, Paleontology: Fossils
Published Synthetic gene helps explain the mysteries of transcription across species
(via sciencedaily.com) Original source 'Random DNA' is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular machinery, a new study finds.
Published Decoding the language of epigenetic modifications
(via sciencedaily.com) Original source Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected cells. A major study now provides important new insights into how complex epigenetic modification signatures regulate the genome. This study will pave the way for new treatments of diseases caused by faulty epigenetic machineries.
Published Tiny worms tolerate Chornobyl radiation
(via sciencedaily.com) Original source A new study finds that exposure to chronic radiation from Chornobyl has not damaged the genomes of microscopic worms living there today -- which doesn't mean that the region is safe, the scientists caution, but suggests that these worms are exceptionally resilient.
Published Researchers explore non-invasive method for sampling drug response
(via sciencedaily.com) Original source Harnessing a pervasive type of cellular messenger shows early experimental promise as a routine way of sampling and monitoring the body's response to prescription drug exposure. Experiments have successfully isolated drug-metabolizing enzymes from extracellular vesicles (EVs), which are widely secreted throughout the body for cellular communication.
Published Lab-grown liver organoid to speed up turtle research, making useful traits easier to harness
(via sciencedaily.com) Original source Researchers developed protocols for growing organoids that mimic a turtle liver, the first organoids developed for a turtle and only the second for any reptile. The discovery will aid deeper study of turtle genetics, including the cause of traits with potential medical applications for humans such as the ability to survive weeks without oxygen.
Published Fossil named 'Attenborough's strange bird' was the first in its kind without teeth
(via sciencedaily.com) Original source A new fossil, named 'Attenborough's strange bird' after naturalist and documentarian Sir David Attenborough, is the first of its kind to evolve a toothless beak. It's from a branch of the bird family tree that went extinct in the mass extinction 66 million years ago, and this strange bird is another puzzle piece that helps explain why some birds -- and their fellow dinosaurs -- went extinct, and others survived to today.
Published Modeling the origins of life: New evidence for an 'RNA World'
(via sciencedaily.com) Original source Scientists provide fresh insights on the origins of life, presenting compelling evidence supporting the 'RNA World' hypothesis. The study unveils an RNA enzyme that can make accurate copies of other functional RNA strands, while also allowing new variants of the molecule to emerge over time. These remarkable capabilities suggest the earliest forms of evolution may have occurred on a molecular scale in RNA, and also bring scientists one step closer to re-creating autonomous RNA-based life in the laboratory.
Published An evolutionary mystery 125 million years in the making
(via sciencedaily.com) Original source Plant biologists have uncovered an evolutionary mystery over 100 million years in the making. It turns out that sometime during the last 125 million years, tomatoes and Arabidopsis thaliana plants experienced an extreme genetic makeover. Just what happened remains unclear. But the mystery surrounds CLV3, a gene key to healthy plant growth and development.
Published Photosynthetic secrets come to light
(via sciencedaily.com) Original source Secrets of photosynthesis have been discovered at atomic level, shedding important new light on this plant super-power that greened the earth more than a billion years ago.
Published Convergent evolution of algal CO2-fixing organelles
(via sciencedaily.com) Original source Researchers identified the proteins of a CO2-fixing organelle, namely, 'pyrenoid,' in the marine algal group Chlorarachniophyta and revealed various pyrenoid-associated proteins among algal groups, suggesting the independent evolution of pyrenoids in different algal groups.
Published Light into the darkness of photosynthesis
(via sciencedaily.com) Original source Researchers succeed at generating 3D visualizations of chloroplasts' copying machines.
Published How virus causes cancer: Potential treatment
(via sciencedaily.com) Original source Researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer. The research points to effective new treatment options for KSHV-associated cancers, including Kaposi's sarcoma, primary effusion lymphoma, and HHV8-associated multicentric Castleman disease.
Published Scientists ID burned bodies using technique used for extracting DNA from woolly mammoths, Neanderthals
(via sciencedaily.com) Original source A technique originally devised to extract DNA from woolly mammoths and other ancient archaeological specimens can be used to potentially identify badly burned human remains, according to research.
Published Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells
(via sciencedaily.com) Original source Neuroscientists say they have found a new function for the SYNGAP1 gene, a DNA sequence that controls memory and learning in mammals, including mice and humans.
Published Measuring electrical conductivity in microorganisms, approaching understanding of microbial ecosystems
(via sciencedaily.com) Original source Researchers have developed an innovative methodology for measuring the electrical conductivity of microbial communities. This methodology holds promise for the development of batteries and electrochemical sensors using microorganisms and may serve as a pivotal tool in elucidating the role of electricity within microbial ecosystems.
Published Scientists develop novel RNA- or DNA-based substances to protect plants from viruses
(via sciencedaily.com) Original source Individually tailored RNA or DNA-based molecules are able to reliably fight off viral infections in plants, according to a new study. The researchers were able to fend off a common virus using the new active substances in up to 90 per cent of cases. They also developed a method for finding substances tailored specifically to the virus. The team has now patented the method.
Published Slimming down a colossal fossil whale
(via sciencedaily.com) Original source A 30 million year-old fossil whale may not be the heaviest animal of all time after all, according to a new analysis by paleontologists. The new analysis puts Perucetus colossus back in the same weight range as modern whales and smaller than the largest blue whales ever recorded.
Published New tool helps decipher gene behavior
(via sciencedaily.com) Original source Scientists have extensively researched the structure and sequence of genetic material and its interactions with proteins in the hope of understanding how our genetics and environment interact in diseases. This research has partly focused on 'epigenetic marks', which are chemical modifications to DNA, RNA, and the associated proteins (known as histones).
Published Radio waves can tune up bacteria to become life-saving medicines
(via sciencedaily.com) Original source Scientists have found a new way to alter the DNA of bacterial cells -- a process used to make many vital medicines including insulin -- much more efficiently than standard industry techniques.
Published Nanocarrier with escape reflex
(via sciencedaily.com) Original source Protein-based drugs must be transported into cells in a way that prevents their immediate degradation. A new approach is intended to ensure that they remain intact only in certain cells, such as cancer cells. A Japanese research team has introduced a nanocarrier that can 'escape' from endosomes before its cargo is destroyed there. This ability to escape is only triggered within the endosomes of certain tumor cells.