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Categories: Biology: Biotechnology, Paleontology: Fossils
Published Macrophages 'eat' insulin-producing cells to regulate insulin after mice have given birth
(via sciencedaily.com) Original source Pregnancy brings a rise in pancreatic beta cells -- the cells that produce insulin. Shortly after birth, these cells return to their normal levels. The mechanisms behind this process had remained a mystery. But now a research group has revealed that white blood cells called macrophages 'eat' these cells.
Published More than 100 'magic mushroom' genomes point the way to new cultivars
(via sciencedaily.com) Original source Scientists have amassed genome data for dozens of 'magic mushroom' isolates and cultivars, with the goal to learn more about how their domestication and cultivation has changed them. The findings may point the way to the production of intriguing new cultivars, say the researchers.
Published Researchers have cracked the cellular code on protein folding, offering hope for new therapeutic avenues for many diseases
(via sciencedaily.com) Original source While we often think of diseases as caused by foreign bodies -- bacteria or viruses -- there are hundreds of diseases affecting humans that result from errors in cellular production of its proteins. A team of researchers recently leveraged the power of cutting-edge technology, including an innovative technique called glycoproteomics, to unlock the carbohydrate-based code that governs how certain classes of proteins form themselves into the complex shapes necessary to keep us healthy.
Published Earliest-known fossil mosquito suggests males were bloodsuckers too
(via sciencedaily.com) Original source Researchers have found the earliest-known fossil mosquito in Lower Cretaceous amber from Lebanon. What's more, the well-preserved insects are two males of the same species with piercing mouthparts, suggesting they likely sucked blood. That's noteworthy because, among modern-day mosquitoes, only females are hematophagous, meaning that they use piercing mouthparts to feed on the blood of people and other animals.
Published Crocodile family tree mapped: New light shed on croc evolution
(via sciencedaily.com) Original source Around 250 million years ago, 700 species of reptiles closely related to the modern-day crocodile roamed the earth, now new research reveals how a complex interplay between climate change, species competition and habitat can help explain why just 23 species of crocodile survive today.
Published New technique efficiently offers insight into gene regulation
(via sciencedaily.com) Original source Researchers have developed a new technique called MAbID. This allows them to simultaneously study different mechanisms of gene regulation, which plays a major role in development and disease. MAbID offers new insights into how these mechanisms work together or against each other.
Published Unlocking the secret strength of marine mussels
(via sciencedaily.com) Original source How do you create strong, yet quick-release connections between living and non-living tissues? This is a question that continues to puzzle bioengineers who aim to create materials that bond together for advanced biomedical applications. Looking to nature for inspiration, this research zeroed in on the marine mussel byssus, a fibrous holdfast, which these bivalve mollusks use to anchor themselves in seashore habitats.
Published Dishing the dirt on human evolution: Why scientific techniques matter in archaeology
(via sciencedaily.com) Original source Scientists should seek answers hidden in the dirt using proven and state-of-the-art archaeological science techniques to support new discoveries about human evolution following recent controversies at a cave site in Africa, says a group of international experts. Their recommendations follow claims published in June of this year that Homo naledi --a small-brained human species -- buried their dead in Rising Star Cave, South Africa, between 335,000 and 241,000 years ago, and may also have decorated the cave walls with engravings.
Published Armed to the hilt: Study solves mystery behind bacteria's extensive weaponry
(via sciencedaily.com) Original source A new study tackles the mystery of why bacteria often carry diverse ranges of weapons. The findings show that different weapons are best suited to different competition scenarios. Short-range weapons help bacteria to invade established communities; long-range weapons are useful once established.
Published Unknown animals were leaving bird-like footprints in Late Triassic Southern Africa
(via sciencedaily.com) Original source Ancient animals were walking around on bird-like feet over 210 million years ago, according to a new study.
Published Clever dosage control mechanism of biallelic genes
(via sciencedaily.com) Original source Researchers have uncovered a mechanism that safeguards the biallelic expression of haploinsufficient genes, shedding light on the importance of having two copies of each chromosome. A study identified the epigenetic regulator MSL2 an 'anti-monoallelic' factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes.
Published Researchers decipher enzyme scissors of intestinal microbes
(via sciencedaily.com) Original source Fruit and vegetables contain a variety of plant natural products such as flavonoids, which give fruits their colour and are said to have health-promoting properties. Most plant natural products occur in nature as glycosides, i.e. chemical compounds with sugars. In order for humans to absorb the healthy plant natural products, the sugar must be split off in the intestine. Microorganisms in the intestinal flora help to speed up the process. So-called C-glycosides, i.e. plant natural products with a carbon-based bond to a sugar, would even be practically indigestible without the intestinal microbes (e.g. nothofagin in rooibos tea).
Published Releasing brakes on biocatalysis
(via sciencedaily.com) Original source Enzymes from microorganisms can produce hydrogen (H2) under certain conditions, which makes them potential biocatalysts for biobased H2 technologies. In order to make this hydrogen production efficient, researchers are trying to identify and eliminate possible limiting factors. These include formaldehyde, which occurs naturally as a metabolic product in cells and inhibits the particularly efficient [FeFe] hydrogenase.
Published Landscape dynamics determine the evolution of biodiversity on Earth
(via sciencedaily.com) Original source A landmark study into the geological timescale distribution of sediment and nutrients over 500 million years shows that species biodiversity on Earth is driven by landscape dynamics.
Published Tracing the evolution of the 'little brain'
(via sciencedaily.com) Original source The evolution of higher cognitive functions in humans has so far mostly been linked to the expansion of the neocortex. Researchers are increasingly realizing, however, that the 'little brain' or cerebellum also expanded during evolution and probably contributes to the capacities unique to humans. A research team has now generated comprehensive genetic maps of the development of cells in the cerebella of human, mouse and opossum. Comparisons of these maps reveal both ancestral and species-specific cellular and molecular characteristics of cerebellum development.
Published Nano-sized cell particles are promising intervention tool in treating infectious diseases
(via sciencedaily.com) Original source Extracellular vesicles were found to inhibit the viral infection of COVID-19 and potentially other infectious diseases.
Published Scientists harness flower 'super power' to pave the way for new drug treatments
(via sciencedaily.com) Original source Researchers have developed a way of joining up the head and tail of a protein, making it more stable and easier to get into cells.
Published Scientists find both potential threats and promising resources in the thriving colonies of bacteria and fungi on ocean plastic trash
(via sciencedaily.com) Original source Scientists have found both potential threats and promising resources in the thriving colonies of bacteria and fungi on plastic trash washed up on shores.
Published New clues into the head-scratching mystery of itch
(via sciencedaily.com) Original source Scientists show for the first time that bacteria can cause itch by activating nerve cells in the skin. The findings can inform new therapies to treat itch that occurs in inflammatory skin conditions like eczema and dermatitis.
Published Earliest known European common hippopotamus fossil reveals their Middle Pleistocene dispersal
(via sciencedaily.com) Original source Modern hippos first dispersed in Europe during the Middle Pleistocene, according to a new study.