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Categories: Biology: Biotechnology, Paleontology: Fossils
Published New ribozyme can make RNA molecules accessible for click chemistry in living cells


Important progress for RNA research: A team has discovered a new ribozyme that can label RNA molecules in living cells.
Published 3D-printed 'living material' could clean up contaminated water


A 'living material,' made of a natural polymer combined with genetically engineered bacteria, could offer a sustainable and eco-friendly solution to clean pollutants from water. Researchers developed their living material using a seaweed-based polymer and bacteria that have been programmed to produce an enzyme that transforms various organic pollutants into harmless compounds. In tests, heir material decontaminated water solutions tainted with a pollutant from textile manufacturing: indigo carmine, a blue dye that is used to color denim.
Published Red blood cells exposed to oxygen deficiency protect against myocardial infarction



Red blood cells exposed to oxygen deficiency protect against myocardial infarction, according to a new study. The study also shows that the protective effect is enhanced by a nitrate-rich vegetable diet.
Published Mutation rates in whales are much higher than previously reported



An international team of marine scientists has studied the DNA of family groups from four different whale species to estimate their mutation rates. Using the newly determined rates, the group found that the number of humpback whales in the North Atlantic before whaling was 86 percent lower than earlier studies suggested.
Published Newly discovered fungus helps destroy a harmful food toxin



Patulin is a harmful mycotoxin produced by fungi typically found in damaged fruits, including apples, pears, and grapes. In a recent breakthrough, researchers identified a new filamentous fungal strain that can degrade patulin by transforming it into less toxic substances. Their findings provide important insights into the degradation mechanisms for patulin found in nature, and can lead to new ways of controlling patulin toxicity in our food supplies.
Published The search for the super potato



As climate change continues to pose severe challenges to ensuring sustainable food supplies around the world, scientists are looking for ways to improve the resilience and nutritional quality of potatoes. Scientists have assembled the genome sequences of nearly 300 varieties of potatoes and its wild relatives to develop more nutritious, disease-free, and weather-proof crop. A team has now created a potato super pangenome to identify genetic traits that can help produce the next super spud.
Published How some ion channels form structures permitting drug delivery



A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a new study. The discovery is a significant advance in cell biology, likely solves a long-standing mystery about an unusual feature of some ion channels and has implications for the development of drugs targeting these proteins and for drug delivery.
Published Europe's very own dinosaurs -- the enigmatic Late Cretaceous rhabdodontids



A new study brings together intriguing details about the little-known Rhabdodontidae dinosaurs of Late Cretaceous Europe. These gregarious herbivores, characterized by robust builds and beaks specialized for tough vegetation, inhabited the European archipelago. Despite being widespread and abundant, they vanished in Western Europe due to environmental changes around 69 million years ago, while surviving longer in Eastern Europe. Their fossil record offers valuable insights into their evolution and lifestyle, although its limited nature still challenges comprehensive understanding.
Published Inhalable molecules neutralize SARS-CoV-2 in mice, study finds



Nanofitins, which are derived from a protein in an archaeal microorganism found in hot springs -- successfully neutralized SARS-CoV-2 in mice and were well-tolerated. When inhaled by the rodents, the engineered nanofitins, which inhibit the virus by binding to its spike proteins, were observed to quickly reach the lungs in high doses both preventing and clearing early infections, researchers report.
Published New 'droplet battery' could pave the way for miniature bio-integrated devices


Researchers have developed a miniature battery that could be used to power tiny devices integrated into human tissues. The design uses an ionic gradient across a chain of droplets -- inspired by how electric eels generate electricity. The device was able to regulate the biological activity of human neurons. This could open the way to the development of tiny bio-integrated devices, with a range of applications in biology and medicine.
Published Newly engineered versions of bacterial enzyme reveal how antibiotics could be more potent



Researchers applied a new technology to generate the full inventory of mutations in the bacterial species Escherichia coli where the antibiotic rifampicin attaches to and disables an essential bacterial enzyme known as RNA polymerase (RNAP).
Published Enhancing cancer therapy using functionalized photosynthetic bacteria



Selective targeting of cancerous cells poses major clinical challenges during cancer therapy. However, this limitation can be overcome by using bioengineered bacteria with highly optimized chemical modifications. A recent study demonstrates the use of chemically modified purple photosynthetic bacteria for the successful detection and elimination of colon cancer cells in a mouse model. The study also sheds light on the underlying mechanism of action.
Published Three-eyed distant relative of insects and crustaceans reveals amazing detail of early animal evolution



Scientists use cutting edge scanning technology to reconstruct 'fossil monster' that lived half a billion years ago. The creature's soft anatomy was well-preserved, allowing it to be imaged almost completely: It fills a gap in our understanding of the evolution of arthropods such as insects and crustaceans.
Published Wastewater pipe dig reveals 'fossil treasure trove'



A new article describes the 266 fossil species as one of the richest and most diverse groups of three-million-year-old fauna ever found in New Zealand. At least ten previously unknown species will be described and named in future research. Fossils of the world's oldest known flax snails, an extinct sawshark spine, and great white shark teeth have all been found in a mound of sand excavated from beneath Mangere Wastewater Treatment Plant in 2020.
Published Scientists invent new way to sort cells by type using light


Researchers have developed and demonstrated a new method for high-throughput single-cell sorting that uses stimulated Raman spectroscopy rather than the traditional approach of fluorescence-activated cell sorting. The new approach could offer a label-free, nondestructive way to sort cells for a variety of applications, including microbiology, cancer detection and cell therapy.
Published Unlocking the secrets of cell antennas



The NSL (non-specific lethal) complex regulates thousands of genes in fruit flies and mammals. Silencing the NSL genes leads to the death of the organism, which gave the complex its curious name. Researchers have now discovered that the genes regulated by the NSL complex also include genes of the intraciliary transport system. This enables different cell types to form cilia on their surface, which are important for cell communication. The study shows that these genes are 'switched on' by the NSL complex, regardless of whether a particular cell has cilia or not. The researchers found that this class of cilia-associated genes is crucial for the function of podocytes. This is a highly specialized cell type of the kidney that, paradoxically, does not have cilia. These findings have important implications for ciliopathies and kidney disease.
Published Pros and cons of ChatGPT plugin, Code Interpreter, in education, biology, health


Researchers see potential in educational settings for the newest official ChatGPT plugin, called Code Interpreter, they've found limitations for its use by scientists who work with biological data utilizing computational methods to prioritize targeted treatment for cancer and genetic disorders.
Published Epigenetic mechanism that causes bitter taste distortion discovered



A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens. A new study sheds light on the mechanisms involved in the complex interplay between taste perception and immune function. Their work also highlights the potential of a sequencing tool for investigating epigenetic mechanisms that affect taste-cell gene expression.
Published Researchers describe rebuilding, regenerating lung cells



Researchers have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new ways for treating lung diseases, such as emphysema, pulmonary fibrosis and COVID-19. The two studies describe the methodologies for engineering lung stem cells and transplanting them into injured experimental lungs without immunosuppression.
Published The 'treadmill conveyor belt' ensuring proper cell division



Researchers have discovered how proteins work in tandem to regulate 'treadmilling', a mechanism used by the network of microtubules inside cells to ensure proper cell division.