Computer Science: General Offbeat: Computers and Math Offbeat: General
Published

Say 'aah' and get a diagnosis on the spot: is this the future of health?      (via sciencedaily.com)     Original source 

A computer algorithm has achieved a 98% accuracy in predicting different diseases by analyzing the color of the human tongue. The proposed imaging system can diagnose diabetes, stroke, anemia, asthma, liver and gallbladder conditions, COVID-19, and a range of vascular and gastrointestinal issues, according to new research.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Biology: Zoology Ecology: Research
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Pit-building venom mixers      (via sciencedaily.com)     Original source 

Researchers show that the adaptation of antlions to their ecological niche has also changed their venom. They compared the venom system of antlion and closely related green lacewing larvae. Antlions produce a much more complex venom from three different venom glands than lacewing larvae do. All the venom proteins identified come from the insects themselves, not from symbiotic bacteria. Some of the toxins are new and appear to be unique to antlions. Waiting for their victims in pitfall traps in the sand, antlions can use their venom to immobilize larger prey. The venom therefore plays an important ecological role in adapting to their barren habitat.

Biology: Biochemistry Biology: Biotechnology Biology: General Biology: Zoology Environmental: General Environmental: Water Geoscience: Environmental Issues Geoscience: Geochemistry Offbeat: Earth and Climate Offbeat: General Offbeat: Plants and Animals
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Reduce, reuse, 're-fly-cle'      (via sciencedaily.com)     Original source 

Black soldier flies are now commercially used to consume organic waste -- but genetic modifications proposed by bioscientists could see the insects digesting a wider variety of refuse, while also creating raw ingredients for industry.

Computer Science: Artificial Intelligence (AI) Computer Science: General Engineering: Robotics Research Offbeat: Computers and Math Offbeat: General Offbeat: Space Space: Exploration Space: General
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Engineers make tunable, shape-changing metamaterial inspired by vintage toys      (via sciencedaily.com)     Original source 

Common push puppet toys in the shapes of animals and popular figures can move or collapse with the push of a button at the bottom of the toys' base. Now, a team of engineers has created a new class of tunable dynamic material that mimics the inner workings of push puppets, with applications for soft robotics, reconfigurable architectures and space engineering.

Mathematics: Modeling Offbeat: Computers and Math Offbeat: General
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AI poses no existential threat to humanity, new study finds      (via sciencedaily.com)     Original source 

Large Language Models (LLMs) are entirely controllable through human prompts and lack 'emergent abilities'; that is, the means to form their own insights or conclusions. Increasing model size does not lead LLMs to gain emergent reasoning abilities, meaning they will not develop hazardous abilities and therefore do not pose an existential threat. A new study sheds light on the (until now unexplained) capabilities and shortcomings of LLMs, including the need for carefully engineered prompts to exhibit good performance.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
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Researchers ID body's 'quality control' regulator for protein folding      (via sciencedaily.com)     Original source 

Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease. Fortunately, our bodies have a quality-control system that identifies misfolded proteins and marks them either for additional folding work or destruction, but how, exactly, this quality-control process functions is not entirely known. Researchers have now made a major leap forward in our understanding of how this quality-control system works by discovering the 'hot spot' where all the action takes place.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology
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Low magnesium levels increase disease risk      (via sciencedaily.com)     Original source 

A new study has identified why a diet rich in magnesium is so important for our health, reducing the risk of DNA damage and chronic degenerative disorders.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Biology: Molecular
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Taking a 'one in a million' shot to tackle dopamine-linked brain disorders      (via sciencedaily.com)     Original source 

With the help of a tiny, transparent worm called Caenorhabditis elegans, researchers have identified novel players in dopamine signaling by taking advantage of a powerful platform generated via the Million Mutation Project (MMP) for the rapid identification of mutant genes based on their functional impact. They can seek insights from simpler organisms whose genes bear striking similarity to those found in humans and where opportunities for genetic insights to disease can be pursued more efficiently and inexpensively.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
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An appetizer can stimulate immune cells' appetite, a boon for cancer treatments      (via sciencedaily.com)     Original source 

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer. Chief among this force is the macrophage, a white blood cell that surveils tissues and consumes pathogens, debris, dead cells, and cancer. Macrophages have a delicate task. It's crucial that they ignore healthy cells while on patrol, otherwise they could trigger an autoimmune response while performing their duties.

Biology: Biochemistry Biology: Biotechnology Biology: General Ecology: Trees Environmental: General Geoscience: Environmental Issues Geoscience: Geochemistry
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New genetically engineered wood can store carbon and reduce emissions      (via sciencedaily.com)     Original source 

Researchers genetically modified poplar trees to produce high-performance, structural wood without the use of chemicals or energy intensive processing.

Energy: Technology Offbeat: Computers and Math Offbeat: General Physics: Optics
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Engineers bring efficient optical neural networks into focus      (via sciencedaily.com)     Original source 

Researchers have published a programmable framework that overcomes a key computational bottleneck of optics-based artificial intelligence systems. In a series of image classification experiments, they used scattered light from a low-power laser to perform accurate, scalable computations using a fraction of the energy of electronics.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Microbiology Biology: Molecular Biology: Zoology
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A new mechanism for shaping animal tissues      (via sciencedaily.com)     Original source 

A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams have now found a mechanism by which tissues can be 'programmed' to transition from a flat state to a three-dimensional shape.

Biology: Biochemistry Biology: Biotechnology Biology: General Biology: Microbiology
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New two-step flu vaccine strategy shows promise in pig model      (via sciencedaily.com)     Original source 

A new, two-step flu vaccination strategy that pairs intramuscular injection of a viral vectored flu vaccine with nasal spray administration of a novel attenuated live flu virus appears to be safe and effective in pigs, researchers report.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
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Largest protein yet discovered builds algal toxins      (via sciencedaily.com)     Original source 

While seeking to unravel how marine algae create their chemically complex toxins, scientists have discovered the largest protein yet identified in biology. Uncovering the biological machinery the algae evolved to make its intricate toxin also revealed previously unknown strategies for assembling chemicals, which could unlock the development of new medicines and materials.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Machine learning approach helps researchers design better gene-delivery vehicles for gene therapy      (via sciencedaily.com)     Original source 

Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient. Now, researchers have developed a machine-learning approach that promises to speed up AAV engineering for gene therapy. The tool helps researchers engineer the protein shells of AAVs, called capsids, to have multiple desirable traits, such as the ability to deliver cargo to a specific organ but not others or to work in multiple species. Other methods only look for capsids that have one trait at a time.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
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Bacteria encode hidden genes outside their genome--do we?      (via sciencedaily.com)     Original source 

A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.

Computer Science: Quantum Computers Offbeat: Computers and Math Offbeat: General
Published

Achieving quantum memory in the hard X-ray range      (via sciencedaily.com)     Original source 

Physicists have used Doppler-shifted nuclear resonant absorbers to form a nuclear frequency comb, enabling a quantum memory in the notoriously difficult X-ray range.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology Ecology: Nature Environmental: General Geoscience: Environmental Issues
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Researchers make breakthrough in understanding species abundance      (via sciencedaily.com)     Original source 

The key finding was that temperature and genome size, not body size, had the greatest influence on the maximum population growth rate of the diatoms. Yet body size still mattered in colder latitudes, conserving Bermann's Rule.