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Categories: Biology: Biotechnology, Offbeat: Earth and Climate
Published Researchers discover disease-causing stem cells in lungs of cystic fibrosis patients



Experts in cloning and stem cell science are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis, and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.
Published A close-up of biological nanomachines: Researchers take a deep look at peroxisomal processes


The cell organelles known as 'peroxisomes' dispose toxic substances and fats in the human body, among other things, and, in doing so, they prevent serious illnesses. The 'Pex' group of proteins (peroxisomes biogenesis factors) keep these 'detox units' functioning properly -- and now researchers have shown, at the atomic level, how these highly complex processes proceed.
Published Genetically engineering associations between plants and nitrogen-fixing microbes could lessen dependence on synthetic fertilizer



Nitrogen is an essential nutrient for plant growth, but the overuse of synthetic nitrogen fertilizers in agriculture is not sustainable. A team of bacteriologists and plant scientists discuss the possibility of using genetic engineering to facilitate mutualistic relationships between plants and nitrogen-fixing microbes called 'diazotrophs.' These engineered associations would help crops acquire nitrogen from the air by mimicking the mutualisms between legumes and nitrogen-fixing bacteria.
Published Antibiotics can help some bacteria survive for longer



Scientists have found a surprising effect of some antibiotics on certain bacteria -- that the drugs can sometimes benefit bacteria, helping them live longer.
Published Discovery in mosquitoes could lead to new strategy against dengue fever and other mosquito-borne vectors



Researchers have made an important finding about Aedes aegypti mosquitoes -- one that could one day lead to better methods for reducing the mosquito-to-human transmission of dengue, yellow fever, Zika, and other harmful and sometimes deadly viruses.
Published Same genes behind heart muscle disorders in humans and Dobermanns



Researchers have made a significant finding in determining the genetic background of dilated cardiomyopathy in Dobermanns. This research helps us understand the genetic risk factors related to fatal diseases of the heart muscle and the mechanisms underlying the disease, and offers new tools for their prevention.
Published Conversations with plants: Can we provide plants with advance warning of impending dangers?



Plant scientists have engineered a light-controlled gene expression system (optogenetics system) from a prokaryotic system into a eukaryotic system that is tailored for plants.
Published This parasitic plant convinces hosts to grow into its own flesh--it's also an extreme example of genome shrinkage



Balanophora shed one third of its genes as it evolved into a streamlined parasitic plant -- an extreme degree of genome shrinkage even among parasites. Along the way this subtropical plant developed the ability to induce the host plant to grow into the parasite's own flesh -- forming chimeric organs that mix host and parasite tissues.
Published Researchers develop first method to study microRNA activity in single cells


Researchers have developed the first method to uncover the tasks that microRNAs perform in single cells. This is a huge improvement over existing state-of-the-art methods that require millions of cells and will for the first time allow researchers to study microRNAs in complex tissues such as brains.
Published Split gene-editing tool offers greater precision


To make a gene-editing tool more precise and easier to control, engineers split it into two pieces that only come back together when a third molecule is added.
Published Unzipping mRNA rallies plant cells to fight infection



Living things from plants to humans must constantly adjust the chemical soup of proteins -- the workhorse molecules of life -- inside their cells to adapt to stress or changing conditions. Now, researchers have identified a previously unknown molecular mechanism that helps explain how they do it. A team now reveals hairpin-like structures of mRNA that, by zipping and unzipping, help cells change the mix of proteins they produce when under stress.
Published Genetically modifying individual cells in animals



Researchers have developed a method that lets them genetically modify each cell differently in animals. This allows them to study in a single experiment what used to require many animal experiments. Using the new method, the researchers have discovered genes that are relevant for a severe rare genetic disorder.
Published Sometimes beneficial, sometimes damaging: The double role of the enzyme chameau



Biologists have discovered why an enzyme is important for the survival of fruit flies, even though it can shorten their lives under certain conditions.
Published A newly identified virus emerges from the deep



Marine virologists analyzed sediment from the Mariana Trench, the deepest place on Earth, and identified a new bacteriophage.
Published Spider silk is spun by silkworms for the first time, offering a green alternative to synthetic fibers


Scientists have synthesized spider silk from genetically modified silkworms, producing fibers six times tougher than the Kevlar used in bulletproof vests. The study is the first to successfully produce full-length spider silk proteins using silkworms. The findings demonstrate a technique that could be used to manufacture an environmentally friendly alternative to synthetic commercial fibers such as nylon.
Published Prehistoric fish fills 100 million year gap in evolution of the skull



X-rays of an ancient jawless fish shows earliest-known example of internal cartilage skull, unlike that of any other known vertebrate.
Published Researchers issue urgent call to save the world's largest flower -Rafflesia -- from extinction



A new study finds that most Rafflesia species, which produce the world's largest flowers, face extinction. Lack of protection at local, national, and international levels means that remaining populations are under critical threat.
Published Fast-track strain engineering for speedy biomanufacturing


Using engineered microbes as microscopic factories has given the world steady sources of life-saving drugs, revolutionized the food industry, and allowed us to make sustainable versions of valuable chemicals previously made from petroleum. But behind each biomanufactured product on the market today is the investment of years of work and many millions of dollars in research and development funding. Scientists want to help the burgeoning industry reach new heights by accelerating and streamlining the process of engineering microbes to produce important compounds with commercial-ready efficiency.
Published 16 strange new parasitoid wasp species discovered in Vietnam



Researchers have discovered 16 new species of strange-looking parasitoid wasps from the Loboscelidia group. The study also revealed for the first time the unique parasitic behavior of a captive female from one species, who after parasitizing her host egg, buried the egg in a hole in the soil.
Published Tiny sea creatures reveal the ancient origins of neurons



A new study sheds new light on the origins of modern brain cells. Researchers find evidence that specialized secretory cells found in placozoans, tiny sea creatures the size of a grain of sand, have many similarities to the neuron, such as the genes required to create a partial synapse. From an evolutionary point of view, early neurons might have started as something like these cells, eventually gaining the ability to create a complete synapse, form axons and dendrites and create ion channels that generate fast electrical signals -- innovations which gave rise to the neuron in more complex animals such as jellyfish. Though the complete story of how the first neuron appeared remains to be told, the study demonstrates that the basic building blocks for our brain cells were forming in the ancestors of placozoans grazing inconspicuously in the shallow seas of Earth around 800 million years ago.