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Categories: Biology: Biotechnology, Chemistry: Biochemistry
Published Surprising mechanism for removing dead cells identified
(via sciencedaily.com) Original source A tandem signaling process turns ordinary cells into an efficient cleanup crew.
Published Biophysics: From filament pick-up sticks to active foams
(via sciencedaily.com) Original source Physicists have developed a new model that describes how filaments assemble into active foams.
Published Molecular wires with a twist
(via sciencedaily.com) Original source Researchers have developed molecular wires with periodic twists. By controlling the lengths of regions between twists, the electrical conductivity of individual polymer chains can be enhanced. This work may lead to novel organic electronics or single-molecule wires.
Published Researchers teaching artificial intelligence about frustration in protein folding
(via sciencedaily.com) Original source Scientists have found a new way to predict how proteins change their shape when they function, which is important for understanding how they work in living systems. While recent artificial intelligence (AI) technology has made it possible to predict what proteins look like in their resting state, figuring out how they move is still challenging because there is not enough direct data from experiments on protein motions to train the neural networks.
Published New worm study paves way for better RNA-based drugs to treat human disease
(via sciencedaily.com) Original source Researchers have discovered RNA mechanisms that may lead to more effective, durable and targeted treatments for conditions like high cholesterol, liver diseases and cancers.
Published Explanation found for X-ray radiation from black holes
(via sciencedaily.com) Original source Researchers have succeeded in something that has been pursued since the 1970s: explaining the X-ray radiation from the black hole surroundings. The radiation originates from the combined effect of the chaotic movements of magnetic fields and turbulent plasma gas.
Published Deadly sea snail toxin could be key to making better medicines
(via sciencedaily.com) Original source Scientists are finding clues for how to treat diabetes and hormone disorders in an unexpected place: a toxin from one of the most venomous animals on the planet.
Published 'Molecular compass' points way to reduction of animal testing
(via sciencedaily.com) Original source Machine learning models have become increasingly popular for risk assessment of chemical compounds. However, they are often considered 'black boxes' due to their lack of transparency. To increase confidence in these models, researchers proposed carefully identifying the areas of chemical space where these models are weak. They developed an innovative software tool for this purpose, and the results of this research approach have just been published.
Published A new reaction to enhance aromatic ketone use in chemical synthesis
(via sciencedaily.com) Original source Researchers develop a one pot process to transform aromatic ketones to esters, offering advancements in pharmaceutical synthesis and materials science.
Published Investigating the interplay of folding and aggregation in supramolecular polymer systems
(via sciencedaily.com) Original source Scientists have developed photoresponsive supramolecular polymers that can undergo both intrachain folding and interchain aggregation.
Published Adaptive 3D printing system to pick and place bugs and other organisms
(via sciencedaily.com) Original source A new adaptive 3D printing system can identify the positions of randomly distributed organisms and safely move them to specific locations for assembly.
Published Scientists discover new code governing gene activity
(via sciencedaily.com) Original source A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists' understanding of gene regulation and how genetic variations may influence gene expression in development or disease.
Published Scientists harness quantum microprocessor chips for revolutionary molecular spectroscopy simulation
(via sciencedaily.com) Original source Engineering researchers have successfully developed a quantum microprocessor chip for molecular spectroscopy simulation of actual large-structured and complex molecules.
Published Researchers uncover the secrets of 'plant puberty'
(via sciencedaily.com) Original source Researchers have identified the genetic changes linked to why plants go through a developmental change similar to 'puberty' at different rates, a discovery which could lead to better crop nutrition.
Published Peering into the mind of artificial intelligence to make better antibiotics
(via sciencedaily.com) Original source Artificial intelligence (AI) has exploded in popularity as of late. But just like a human, it's hard to read an AI model's mind. Explainable AI (XAI) could help us do just that by providing justification for a model's decisions. And now, researchers are using XAI to scrutinize predictive AI models more closely, which could help make better antibiotics.
Published Key biofuel-producing microalga believed to be a single species is actually three
(via sciencedaily.com) Original source When a global pandemic forced previous a graduate student out of the lab and onto the computer, he found a world of difference hidden in the long-studied species of Botryoccocus braunii -- and discovered that it isn't one species at all, but three.
Published Wearable, stretchable sensor for quick, continuous, and non-invasive detection of solid-state skin biomarkers
(via sciencedaily.com) Original source Detecting diseases early requires the rapid, continuous and convenient monitoring of vital biomarkers. Researchers have now developed a novel sensor that enables the continuous, and real-time detection of solid-state epidermal biomarkers, a new category of health indicators. The team's wearable, stretchable, hydrogel-based sensor overcomes the limitations of current methods that rely on biofluid samples, such as blood, urine and sweat. This makes it a promising alternative for wearable, continuous, and real-time health monitoring, facilitating the early detection of conditions such as cardiovascular diseases and stroke.
Published New insights on how bird flu crosses the species barrier
(via sciencedaily.com) Original source The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's polymerase when it interacts with a human protein essential for the virus to replicate within the cell. The structure of this replication complex provides important information about the mutations that avian influenza polymerase must undergo to adapt to mammals, including humans. These results can help scientists monitor the evolution and adaptability of bird flu strains, such as H5N1 or H7N9, towards infecting other species.
Published Searching old stem cells that stay young forever
(via sciencedaily.com) Original source The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists have now identified possible candidates for multipotent stem cells in the sea anemone for the first time. These stem cells are regulated by evolutionary highly conserved genes.
Published Morphable materials: Researchers coax nanoparticles to reconfigure themselves
(via sciencedaily.com) Original source A view into how nanoscale building blocks can rearrange into different organized structures on command is now possible with an approach that combines an electron microscope, a small sample holder with microscopic channels, and computer simulations, according to a new study.