Showing 20 articles starting at article 41

< Previous 20 articles        Next 20 articles >

Categories: Biology: Biotechnology

Return to the site home page

     (via sciencedaily.com)     Original source 

While seeking to unravel how marine algae create their chemically complex toxins, scientists have discovered the largest protein yet identified in biology. Uncovering the biological machinery the algae evolved to make its intricate toxin also revealed previously unknown strategies for assembling chemicals, which could unlock the development of new medicines and materials.

     (via sciencedaily.com)     Original source 

Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient. Now, researchers have developed a machine-learning approach that promises to speed up AAV engineering for gene therapy. The tool helps researchers engineer the protein shells of AAVs, called capsids, to have multiple desirable traits, such as the ability to deliver cargo to a specific organ but not others or to work in multiple species. Other methods only look for capsids that have one trait at a time.

     (via sciencedaily.com)     Original source 

A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.

     (via sciencedaily.com)     Original source 

A new artificial intelligence model can predict how different proteins may bind to DNA.

     (via sciencedaily.com)     Original source 

The key finding was that temperature and genome size, not body size, had the greatest influence on the maximum population growth rate of the diatoms. Yet body size still mattered in colder latitudes, conserving Bermann's Rule.

     (via sciencedaily.com)     Original source 

An interdisciplinary team of medical and engineering researchers has spent the last six years working to unlock a significant piece of the puzzle in the search for a cure: how and where the gluten response begins.

     (via sciencedaily.com)     Original source 

Researchers develop a microstructured 'artificial lung' model using bioprinting technology.

     (via sciencedaily.com)     Original source 

Scientists have developed a new way of counting labelled proteins in living cells that could become a standard and valuable tool in the field of biomedical research.

     (via sciencedaily.com)     Original source 

There comes a point in the lives of young owl monkeys when they leave their parents and strike out on their own to find a mate. In a new study of a wild population of Azara's owl monkeys in northern Argentina, researchers reveal that a combination of social and ecological factors influences when these tree-dwelling monkeys peel away from their parents and siblings. According to their findings -- which were based on 25 years of genetic and demographic data for several generations of owl monkeys, covering more than 330 individuals -- none of the individuals, regardless of their sex, reproduced in the same group where they were born. In all cases, the researchers found, the animals either departed from their natal group or died before reproducing.

     (via sciencedaily.com)     Original source 

Scientists discovered a role played by ribosomes during the folding of new proteins in cells.

     (via sciencedaily.com)     Original source 

A viral defense mechanism can be used to accelerate the creation of female stem cell lines in mice. The findings can boost efforts in medical research, drug testing, and regenerative therapies, particularly for women and individuals with two X chromosomes.

     (via sciencedaily.com)     Original source 

Researchers have discovered two proteins that work in tandem to control an important response to cell stress.

     (via sciencedaily.com)     Original source 

Elephant conservation is a major priority in southern Africa, but habitat loss and urbanization mean the far-ranging pachyderms are increasingly restricted to protected areas like game reserves. The risk? Contained populations could become genetically isolated over time, making elephants more vulnerable to disease and environmental change.

     (via sciencedaily.com)     Original source 

Fur is a defining characteristic of mammals, coming in a wide variety of colors and patterns -- thanks to a world-first study, we now know which genes make a marsupial's coat black or grey.

     (via sciencedaily.com)     Original source 

Researchers reveal more about the tit-for-tat evolutionary changes occurring in both potato plants and the pathogen that caused the 1840s Irish potato famine.

     (via sciencedaily.com)     Original source 

With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its rules and context to draw functional information about the DNA sequences.

     (via sciencedaily.com)     Original source 

A previously unknown defence mechanism in the brain prevents herpesvirus from infecting the brain's nerve cells.

     (via sciencedaily.com)     Original source 

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue swelling and inflammation. Now, researchers have discovered a hidden talent of mast cells: they can capture and use another type of immune cell called neutrophils. This surprising discovery sheds new light on how our immune system works, particularly during allergic reactions.

     (via sciencedaily.com)     Original source 

Scientists found that decreasing folate intake can support healthier metabolisms in aging animal models, challenging the conventional belief that high folate consumption universally benefits health.

     (via sciencedaily.com)     Original source 

The process by which phages -- viruses that infect and replicate within bacteria -- enter cells has been studied for over 50 years. In a new study, researchers have used cutting-edge techniques to look at this process at the level of a single cell.