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Categories: Biology: Cell Biology, Chemistry: Inorganic Chemistry

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Researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease. The study found phenylacetylglutamine (PAG), produced by gut bacteria as a waste product, then absorbed and formed in the liver, interacts with previously undiscovered locations on beta-2 adrenergic receptors on heart cells once it enters the circulation.

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Finding the next groundbreaking polymer is always a challenge, but now researchers are using artificial intelligence (AI) to shape and transform the future of the field.

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If you've visited a trendy cafe in the past few years, you might have noticed 'golden' turmeric milk on the menu. This fancy drink is caffeine-free, coffee-free and can even be vegan. And now, researchers have developed an efficient method to make a powdered, plant-based, instant version that maintains the beneficial properties of the ingredients while also extending its shelf life.

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Some of the attractive hues of brightly colored, cloth-bound books from the Victorian era come from dyes that could pose a health risk to readers, collectors or librarians. The latest research on these 'poison books' used three techniques -- including one that hasn't previously been applied to books -- to assess dangerous dyes in a university collection and found some volumes had levels that might be unsafe.

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When a global pandemic forced previous a graduate student out of the lab and onto the computer, he found a world of difference hidden in the long-studied species of Botryoccocus braunii -- and discovered that it isn't one species at all, but three.

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The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's polymerase when it interacts with a human protein essential for the virus to replicate within the cell. The structure of this replication complex provides important information about the mutations that avian influenza polymerase must undergo to adapt to mammals, including humans. These results can help scientists monitor the evolution and adaptability of bird flu strains, such as H5N1 or H7N9, towards infecting other species.

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The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists have now identified possible candidates for multipotent stem cells in the sea anemone for the first time. These stem cells are regulated by evolutionary highly conserved genes.

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A new animal study shows that exposure to immune-stimulating proteins left behind by COVID-19 leads to lower cortisol, brain inflammation and a heightened reaction to subsequent stressors.

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Flexibility and personalization were key in optimizing dieters' weight-loss success on the Individualized Diet Improvement Program, created by food scientists.

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A view into how nanoscale building blocks can rearrange into different organized structures on command is now possible with an approach that combines an electron microscope, a small sample holder with microscopic channels, and computer simulations, according to a new study.

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A new study found that Manuka honey could potentially be an alternative, natural option for breast cancer prevention and treatment -- particularly for estrogen receptor (ER)-positive breast cancer, the most common subtype of breast cancer that accounts for about 70-80% of all breast cancer cases.

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Researchers surveyed the gut microbiomes of nearly 2,000 people, discovering dozens of potential new antibiotics. The lead candidate, prevotellin-2, demonstrated anti-infective capabilities on par with polymyxin B, an FDA-approved antibiotic used today to treat multidrug-resistant infections, suggesting that the human gut microbiome may contain antibiotics that will someday find clinical application.

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Previous scientific studies have indicated that North American dog lineages were replaced with European ones between 1492 and the present day. To better understand the timing of this replacement, researchers sequenced mitochondrial DNA from archaeological dogs. Their findings suggest a complex social history of dogs during the early colonial period.

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Hyperactivity, repetitive behavior, and language deficits all appeared in the mice, highlighting an unexpected role the cerebellum seems to play in autism.

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Researchers developed a novel reagent that enhances the precision of drug synthesis. This innovative method introduces a new sulfur fluoride exchange (SuFEx) reagent that allows for highly controlled production of crucial sulfur-based molecules, including sulfinamides, sulfonimidamides and sulfoximines.

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Society relies heavily on diverse fluidic technologies. The ability to precisely capture and release various chemical and biological fluids plays a fundamental role in many fields. A long-standing challenge is to design a platform that enables the switchable capture and release of liquids with precise spatial and temporal control and accurate volumes of the fluid. Recently, researchers have invented a new method to effectively overcome this challenge.

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A study expands understanding on how electrons move through the conductive parts of complex fluids found in electrochemical devices such as batteries. This work can help overcome existing knowledge gaps for engineers seeking to improve the performance of these devices.

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Giving probiotics to pregnant mice can enhance both the immune system and behavior of the mothers and their offspring.

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Researchers have demonstrated a technique for printing thin metal oxide films at room temperature, and have used the technique to create transparent, flexible circuits that are both robust and able to function at high temperatures.

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Europe's abandoned farmlands could find new life through rewilding, a movement to restore ravaged landscapes to their wilderness before human intervention. A quarter of the European continent, 117 million hectares, is primed with rewilding opportunities, researchers report.