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Categories: Biology: Cell Biology, Chemistry: Organic Chemistry
Published What makes a pathogen antibiotic-resistant?



In a comparative study, researchers describe how two notable pathogens -- Escherichia coli and Acinetobacter baumannii -- employ distinctly different tools to fend off antibiotic attack by two different drugs.
Published Revealing a hidden threat: Researchers show viral infections pose early heart risks



In a potentially game-changing development, scientists have revealed a new understanding of sometimes fatal viral infections that affect the heart. Traditionally, the focus has been on heart inflammation known as myocarditis, which is often triggered by the body's immune response to a viral infection. However, a new study sheds new light on this notion, revealing that the virus itself creates potentially dangerous conditions in the heart before inflammation sets in.
Published Early life adversity leaves long-term signatures in baboon DNA



Early experiences in an animal's life can have a significant impact on its capacity to thrive, even years or decades later, and DNA methylation may help record their effects. In a study of 256 wild baboons, researchers found that resource limitation during early life was associated with many differences in DNA methylation, a small chemical mark on the DNA sequence that can affect gene activity.
Published First heat map for individual red blood cells



Entropy is often associated with disorder and chaos, but in biology it is related to energy efficiency and is closely linked to metabolism, the set of chemical reactions that sustain life. An international research team has now developed a novel methodology for the measurement of entropy production at the scale of a nanometer, meaning one-billionth of a meter. The new approach enabled the scientists to measure the heat flow, known as the entropy production rate, of single red blood cells.
Published Marine algae implants could boost crop yields



Scientists have discovered the gene that enables marine algae to make a unique type of chlorophyll. They successfully implanted this gene in a land plant, paving the way for better crop yields on less land.
Published Revealing the evolutionary origin of genomic imprinting



Some of our genes can be expressed or silenced depending on whether we inherited them from our mother or our father. The mechanism behind this phenomenon, known as genomic imprinting, is determined by DNA modifications during egg and sperm production.
Published Universal tool for tracking cell-to-cell interactions



An updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction.
Published Synthetic gene helps explain the mysteries of transcription across species



'Random DNA' is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular machinery, a new study finds.
Published Decoding the language of epigenetic modifications



Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected cells. A major study now provides important new insights into how complex epigenetic modification signatures regulate the genome. This study will pave the way for new treatments of diseases caused by faulty epigenetic machineries.
Published Deconstructing the structural elements of a lesser-known microbe



Researchers shed light on archaea, intriguing microbes found in extreme environments but also in the human gut microbiome.
Published Genetic mutation in a quarter of all Labradors hard-wires them for obesity



New research finds around a quarter of Labrador retriever dogs face a double-whammy of feeling hungry all the time and burning fewer calories due to a genetic mutation.
Published New type of nanoparticle makes vaccines more powerful



A type of nanoparticle called a metal organic framework (MOF) could be used to deliver vaccines and act as an adjuvant. Researchers find these particles provoke a strong immune response by activating the innate immune system through cell proteins called toll-like receptors.
Published Key advance toward removing common herbicide from groundwater



Chemists are closing in on a new tool for tackling the global problem of weedkiller-tainted groundwater.
Published Aluminum nanoparticles make tunable green catalysts



A nanotechnology pioneer has uncovered a transformative approach to harnessing the catalytic power of aluminum nanoparticles by annealing them in various gas atmospheres at high temperatures.
Published Tiny worms tolerate Chornobyl radiation



A new study finds that exposure to chronic radiation from Chornobyl has not damaged the genomes of microscopic worms living there today -- which doesn't mean that the region is safe, the scientists caution, but suggests that these worms are exceptionally resilient.
Published Researchers explore non-invasive method for sampling drug response



Harnessing a pervasive type of cellular messenger shows early experimental promise as a routine way of sampling and monitoring the body's response to prescription drug exposure. Experiments have successfully isolated drug-metabolizing enzymes from extracellular vesicles (EVs), which are widely secreted throughout the body for cellular communication.
Published Using light to precisely control single-molecule devices



Researchers flip the switch at the nanoscale by applying light to induce bonding for single-molecule device switching.
Published Lab-grown liver organoid to speed up turtle research, making useful traits easier to harness



Researchers developed protocols for growing organoids that mimic a turtle liver, the first organoids developed for a turtle and only the second for any reptile. The discovery will aid deeper study of turtle genetics, including the cause of traits with potential medical applications for humans such as the ability to survive weeks without oxygen.
Published Researchers closing in on genetic treatments for hereditary lung disease, vision loss



Researchers who work with tiny drug carriers known as lipid nanoparticles have developed a new type of material capable of reaching the lungs and the eyes, an important step toward genetic therapy for hereditary conditions like cystic fibrosis and inherited vision loss.
Published 'Like a lab in your pocket' -- new test strips raise game in gene-based diagnostics



Biosensing technology developed by engineers has made it possible to create gene test strips that rival conventional lab-based tests in quality.