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Categories: Biology: Cell Biology, Energy: Batteries
Published Bear genes show circadian rhythms even during hibernation



The internal clocks of grizzly bears appear to keep ticking through hibernation, according to a genetic study. This persistence highlights the strong role of circadian rhythms in the metabolism of many organisms including humans. The genetic study confirmed observational evidence that bears' energy production still waxes and wanes in a daily pattern even as they slumber for several months without eating. The researchers also found that during hibernation the amplitude of the energy production was blunted, meaning the range of highs and lows was reduced. The peak also occurred later in the day under hibernation than during the active season, but the daily fluctuation was still there.
Published Hormones have the potential to treat liver fibrosis



Researchers have discovered previously unknown changes in a specific type of liver cells, potentially opening avenues for a new treatment for liver fibrosis, a potentially life-threatening condition. Currently, there are no drugs available to treat liver fibrosis.
Published How bacteria recognize viral invasion and activate immune defenses



Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.
Published Surveilling wetlands for infectious bird flu -- and finding it



Recently, morning omelets and holiday dinners have gotten more expensive. One likely cause is bird flu, outbreaks of which led to the deaths of millions of chickens and turkeys from infection or culling in 2022, according to the U.S. Department of Agriculture, and which still demands rigorous monitoring of wild populations. Now, researchers have developed a method that detected infectious bird flu virus in wetlands frequented by waterfowl.
Published Colliding ribosomes activate RNA repair



Researchers discover how ribosomes contribute to the recognition and removal of RNA crosslinking damage.
Published Unexpected discovery opens bioengineering opportunities for human and plant health



An unexpected genetic discovery in wheat has led to opportunities for metabolic engineering of versatile compounds with potential to improve its nutritional qualities and resilience to disease.
Published Genetic discovery promises high-iron vegetables and cereals



A genetic breakthrough has opened new opportunities for iron-fortified vegetables and cereal crops to help address the global health issue of anemia.
Published Novel C. diff structures are required for infection, offer new therapeutic targets



Newly discovered iron storage 'ferrosomes' inside the bacterium C. diff -- the leading cause of hospital-acquired infections -- are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do not contain organelles.
Published Using cosmetic ingredient for battery protection



A research team has devised a battery electrode protective film using biopolymers sourced from cosmetic ingredients.
Published Shedding new light on sugars, the 'dark matter' of cellular biology



Chemists have developed a new tool for detecting interactions between sugars and lectins, a discovery that could help in the fight against diseases like cancer.
Published How tiny hinges bend the infection-spreading spikes of a coronavirus



Far from being stiff and pointy, a coronavirus's infectious spikes are shaped like chicken drumsticks with the meaty part facing out, and the meaty part can tilt every which way on its slender stalk. A new study suggests that disabling those hinges could block infection.
Published A tale of two proteins: Fundamental research could make growing better crops like clockwork



Rhomboid-like protein 10, or RBL10, is thought to be an enzyme that degrades other proteins in the chloroplast membrane, but its function is largely unknown. Researchers are studying how RBL10 affects photosynthetic membrane lipid metabolism, an essential process in photosynthesis.
Published Hormonal contraceptives in teens may alter risk assessment, rat study suggests



Hormonal contraceptives taken by adolescents may influence development of the brain in a way that alters the recognition of risks, a new study in rats suggests.
Published Evolution of taste: Early sharks were able to perceive bitter substances



New genetic data show that humans and sharks share bitter taste receptors, even though their evolutionary pathways separated nearly 500 million years ago.
Published New discovery on how green algae count cell divisions illuminates key step needed for the evolution of multicellular life



An international research team has made an unexpected discovery of a biased counting mechanism used by the single-celled green alga Chlamydomonas to control cell division.
Published How marine bristle worms use a special protein to distinguish between sunlight and moonlight



A research team has presented its findings on the functioning of an atypical cryptochrome protein (Cry). These proteins are found in a variety of organisms, and they are often involved in light-controlled biological processes. The marine bristle worm Platynereis dumerilii, for example, employs a special Cry protein designated L-Cry to distinguish between sunlight and moonlight as well as between different moon phases. This is essential for the worms to synchronize their reproduction to the full moon phase via an inner monthly calendar, also called circalunar clock.
Published Cycle of fasting and feeding is crucial for healthy aging



Fasting interventions, which involve alternating periods of fasting and refeeding, are generally thought to improve health. But these interventions don't work as well in old animals. The question is: Why? By studying the short-lived killifish, researchers have shown that older fish deviate from a youthful fasting and refeeding cycle, and instead enter a state of perpetual fasting, even when ingesting food. However, the benefits of refeeding after fasting in old killifish can be restored by genetically activating a specific subunit of AMP kinase, an important sensor of cellular energy. These mutant fish experienced improved health and longevity, indicating that both fasting and refeeding are needed to confer health benefits and act through AMP kinase to do so.
Published Ground-breaking discovery could pave the way for new therapies to prevent cardiovascular disease and stroke



Researchers have discovered the mechanism by which cholesterol in our diet is absorbed into our cells. This discovery opens up new opportunities for therapeutic intervention to control cholesterol uptake that could complement other therapies and potentially save lives.
Published Template for success: Shaping hard carbon electrodes for next-generation batteries



Sodium- and potassium-ion batteries are promising next-generation alternatives to the ubiquitous lithium-ion batteries (LIBs). However, their energy density still lags behind that of LIBs. To tackle this issue, researchers explored an innovative strategy to turn hard carbon into an excellent negative electrode material. Using inorganic zinc-based compounds as a template during synthesis, they prepared nanostructured hard carbon, which exhibits excellent performance in both alternative batteries.
Published Forming ice: There's a fungal protein for that



New research explores how proteins produced by a common fungus trigger ice nucleation at warm temperatures. The study holds potential implications for improving our understanding of how life affects precipitation and climate.