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Categories: Biology: Cell Biology, Energy: Batteries
Published Researchers develop DANGER analysis tool for the safer design of gene editing
(via sciencedaily.com) Original source A team of researchers has developed a software tool that provides a way for the safer design of genome editing in all organisms with a transcriptome. For about a decade, researchers have used the CRISPR technology for genome editing. However, there are some challenges in the use of CRISPR. The new analysis system overcomes these challenges and allows researchers to perform safer on- and off-target assessments without a reference genome. It holds the potential for applications in medicine, agriculture, and biological research.
Published Moving muscle fibers with magnets 'programs' how they align within tissue
(via sciencedaily.com) Original source Stimulating muscle fibers with magnets causes them to grow in the same direction, aligning muscle cells within tissue. The findings offer a simpler, less time-consuming way for medical researchers to program muscle cell alignment, which is strongly tied to healthy muscle function.
Published How cord-like aggregates of bacteria lead to tuberculosis infections
(via sciencedaily.com) Original source The ability of Mycobacterium tuberculosis (MTB), a serious respiratory infection, to form snake-like cords was first noted nearly 80 years ago. Investigators report the biophysical mechanisms by which these cords form and demonstrate how several generations of dividing bacteria hang together to create these structures that enable resistance to antibiotics.
Published Generating clean electricity with chicken feathers
(via sciencedaily.com) Original source Turning unused waste from food production into clean energy: Researchers are using chicken feathers to make fuel cells more cost-effective and sustainable.
Published Soil carried on sea freight loaded with dangerous pests and diseases, research finds
(via sciencedaily.com) Original source While sea freight is recognised as a pathway for the movement of exotic organisms, there is little research that has quantified the risk. Soil collected from the external surfaces of sea freight was found to support live microorganisms, worms, seeds and insects, including various regulated biosecurity organisms. The research confirms that shipping containers provide a pathway for the movement of exotic species.
Published Can golden retrievers live longer?
(via sciencedaily.com) Original source Researchers have found a gene associated with longevity in golden retrievers, one of the most popular breeds of dogs.
Published DNA shows where Washington culvert replacements helped spawning salmon
(via sciencedaily.com) Original source University and federal scientists used genetic sleuthing to study how salmon were affected by two major culvert replacements near the city of Bellingham. One project, a major upgrade under Interstate-5, had a big impact, while the other old culvert may have been less of a barrier to fish. Authors from the UW and NOAA are studying the use of environmental DNA, or eDNA, in future environmental impact reporting.
Published Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents
(via sciencedaily.com) Original source Whether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the 'parenting hub' in the brain, according to a new study.
Published Red meat consumption associated with increased type 2 diabetes risk
(via sciencedaily.com) Original source People who eat just two servings of red meat per week may have an increased risk of developing type 2 diabetes compared to people who eat fewer servings, and the risk increases with greater consumption, according to a new study. Researchers also found that replacing red meat with healthy plant-based protein sources, such as nuts and legumes, or modest amounts of dairy foods, was associated with reduced risk of type 2 diabetes.
Published Physical theory improves protein folding prediction
(via sciencedaily.com) Original source Proteins are important molecules that perform a variety of functions essential to life. To function properly, many proteins must fold into specific structures. However, the way proteins fold into specific structures is still largely unknown. Researchers have developed a novel physical theory that can accurately predict how proteins fold. Their model can predict things previous models cannot. Improved knowledge of protein folding could offer huge benefits to medical research, as well as to various industrial processes.
Published Restoring the function of a human cell surface protein in yeast cells
(via sciencedaily.com) Original source Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into yeast cells. To tackle this issue, researchers developed an innovative strategy to restore GPCR function in yeast cells by inducing random mutations. Their findings can help understand GPCRs better and could pave the way to therapeutic breakthroughs for many diseases.
Published A miniature magnetic resonance imager made of diamond
(via sciencedaily.com) Original source The development of tumors begins with miniscule changes within the body's cells; ion diffusion at the smallest scales is decisive in the performance of batteries. Until now the resolution of conventional imaging methods has not been high enough to represent these processes in detail. A research team has now developed diamond quantum sensors which can be used to improve resolution in magnetic imaging.
Published Cobalt-free battery for cleaner, greener power
(via sciencedaily.com) Original source High-capacity and reliable rechargeable batteries are a critical component of many devices and even modes of transport. They play a key role in the shift to a greener world. A wide variety of elements are used in their production, including cobalt, the production of which contributes to some environmental, economic, and social issues. A team now presents a viable alternative to cobalt which in some ways can outperform state-of-the-art battery chemistry. It also survives a large number of recharge cycles, and the underlying theory can be applied to other problems.
Published Stolen genes allow parasitic control of behavior
(via sciencedaily.com) Original source A research team has discovered that parasites manipulate their hosts using stolen genes that they likely acquired through a phenomenon called horizontal gene transfer.
Published Soft optical fibers block pain while moving and stretching with the body
(via sciencedaily.com) Original source New soft, implantable fibers can deliver light to major nerves through the body. They are an experimental tool for scientists to explore the causes and potential treatments for peripheral nerve disorders in animal models.
Published Yeast speeds discovery of medicinal compounds in plants
(via sciencedaily.com) Original source Researchers have harnessed the power of baker's yeast to create a cost-effective and highly efficient approach for unraveling how plants synthesize medicinal compounds, and used the new method to identify key enzymes in a kratom tree.
Published Study elucidates evolution of mosquitoes and their hosts
(via sciencedaily.com) Original source Study creates a mosquito family tree to better understand disease transmission and host choice.
Published Single vaccine protects against three deadly strains of coronavirus
(via sciencedaily.com) Original source A vaccine designed to protect against three different deadly coronaviruses shows success in mouse studies, demonstrating the viability of a pan-coronavirus vaccine developed by researchers at the Duke Human Vaccine Institute.
Published Scientists uncover new way viruses fight back against bacteria
(via sciencedaily.com) Original source A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas biotechnologies.
Published New insights into the genetics of the common octopus: Genome at the chromosome level decoded
(via sciencedaily.com) Original source Octopuses are fascinating animals -- and serve as important model organisms in neuroscience, cognition research and developmental biology. To gain a deeper understanding of their biology and evolutionary history, validated data on the composition of their genome is needed, which has been lacking until now. Scientists have now been able to close this gap and, in a new study, determined impressive figures: 2.8 billion base pairs -- organized in 30 chromosomes. What sounds so simple is the result of complex, computer-assisted genome analyses and comparisons with the genomes of other cephalopod species.