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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Scientists take major step towards completing the world's first synthetic yeast      (via sciencedaily.com)     Original source 

A team of Scientists has completed construction of a synthetic chromosome as part of a major international project to build the world's first synthetic yeast genome. The work represents completion of one of the 16 chromosomes of the yeast genome, which is part of the biggest project ever in synthetic biology; the international synthetic yeast genome collaboration. The collaboration, known as 'Sc2.0' has been a 15-year project involving teams from around the world (UK, US, China, Singapore, UK, France and Australia), working together to make synthetic versions of all of yeast's chromosomes. Alongside this paper, another 9 publications are also released today from other teams describing their synthetic chromosomes. The final completion of the genome project -- the largest synthetic genome ever -- is expected next year.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: General Biology: Molecular
Published

Obesity linked to neurodegeneration through insulin resistance      (via sciencedaily.com)     Original source 

Researchers have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease. Using the common fruit fly, the research shows that a high-sugar diet -- a hallmark of obesity -- causes insulin resistance in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Ecology: Endangered Species
Published

Plants' ingenious defense against mutational damage      (via sciencedaily.com)     Original source 

How do plants deal with mutations in their 'power stations'? By exploiting randomness to create diversity, say researchers.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Molecular
Published

Some benefits of exercise stem from the immune system      (via sciencedaily.com)     Original source 

Research in mice shows that the anti-inflammatory properties of exercise may arise from immune cells mobilized to counter exercise-induced inflammation. Immune cells prevent muscle damage by lowering levels of interferon, a key driver of chronic inflammation, inflammatory diseases, and aging.

Biology: Biochemistry Biology: Cell Biology Biology: General
Published

Seeing the unseen: How butterflies can help scientists detect cancer      (via sciencedaily.com)     Original source 

There are many creatures on our planet with more advanced senses than humans. Turtles can sense Earth's magnetic field. Mantis shrimp can detect polarized light. Elephants can hear much lower frequencies than humans can. Butterflies can perceive a broader range of colors, including ultraviolet (UV) light.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology
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Viral impostors: Breakthrough for virus research      (via sciencedaily.com)     Original source 

The penetration of viruses into cells can now be tracked with unprecedented accuracy thanks to an innovative design for pseudoviruses.

Anthropology: General Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Biology: Zoology Ecology: Animals
Published

New secrets about cat evolution revealed      (via sciencedaily.com)     Original source 

By comparing genomes of several cat species, the project has helped researchers understand why cat genomes tend to have fewer complex genetic variations (such as rearrangements of DNA segments) than other mammal groups, like primates. It also revealed new insights into which parts of cat DNA are most likely to evolve rapidly and how they play a role in species differentiation.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New antibiotic approach proves promising against lyme bacterium      (via sciencedaily.com)     Original source 

Using a technique that has shown promise in targeting cancer tumors, a team has found a way to deploy a molecular warhead that can annihilate the bacterium that causes Lyme disease.

Biology: Cell Biology Biology: Microbiology Biology: Molecular Chemistry: Biochemistry
Published

Visualizing fungal infections deep in living host tissue reveals proline metabolism facilitates virulence      (via sciencedaily.com)     Original source 

Scientists have published the first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host. The study reveals that the opportunistic human fungal pathogen Candida albicans requires the ability to metabolize proline, an amino acid obtained from the host, to mount virulent infections.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Ecology: Animals
Published

Research outlines how sex differences have evolved      (via sciencedaily.com)     Original source 

Researchers have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

A known environmental hazard can change the epigenetics of cells      (via sciencedaily.com)     Original source 

An international team of researchers has discovered that formaldehyde, a widely spread pollutant and common metabolite in our body, interferes in the epigenetic programming of the cell. This finding expands the knowledge of formaldehyde, previously considered only as a DNA mutagen, and helps establishing a further link with cancer.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Research connecting gut bacteria and oxytocin provides a new mechanism for microbiome-promoted health benefits      (via sciencedaily.com)     Original source 

Researchers found that the hormone oxytocin, known to be involved in regulating feeding and social behavior and until now to be produced mostly in the brain, is also produced in the human intestine. Furthermore, gut resident bacteria L. reuteri can affect the production of gut-made oxytocin, providing the first insights into a mechanism by which these bacteria can influence human health.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology
Published

Observation of a virus attaching to another virus      (via sciencedaily.com)     Original source 

'Satellite' viruses must be in proximity to their 'helper' virus to replicate, but this research reports the first documented case of a satellite virus attaching itself to its helper virus. Out of 50 observed helpers, 40 had a satellite bound. Bioinformatic analysis of the satellite and helper viruses' genomes provides clues as to why the satellite may have evolved to attach to the helper, and suggests this pair may have been co-evolving for about 100 million years.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Immunology: Dysfunction of mitochondria drives the exhaustion of T cells      (via sciencedaily.com)     Original source 

In the immune system's fight against cancer and infections, the T cells often lose their power. Now immunologists may have found a possible explanation for this phenomenon.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology
Published

New antibodies neutralize resistant bacteria      (via sciencedaily.com)     Original source 

Broadly neutralizing antibodies are already being used to fight viruses. This approach could also help to treat infections with multi-resistant bacteria in the future.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New study sheds light on the molecular mechanisms underlying lipid recycling within cells      (via sciencedaily.com)     Original source 

Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers explored the molecular mechanisms leading to the degradation of the phospholipid bilayers making up the cell membranes. Their findings improve our understanding of cellular degradation processes and related metabolic disorders.

Biology: Biochemistry Biology: Cell Biology Biology: General
Published

Making gluten-free, sorghum-based beers easier to brew and enjoy      (via sciencedaily.com)     Original source 

Though beer is a popular drink worldwide, it's usually made from barley, which leaves those with a gluten allergy or intolerance unable to enjoy the frothy beverage. Sorghum, a naturally gluten-free grain, could be an alternative, but complex preparation steps have hampered its widespread adoption by brewers. Now, researchers reporting the molecular basis behind sorghum brewing have uncovered an enzyme that could improve the future of sorghum-based beers.

Biology: Biotechnology Biology: Cell Biology Chemistry: Biochemistry Engineering: Nanotechnology Offbeat: General Offbeat: Plants and Animals
Published

Researchers engineer colloidal quasicrystals using DNA-modified building blocks      (via sciencedaily.com)     Original source 

A new study unveils a novel methodology to engineer colloidal quasicrystals using DNA-modified building blocks. The implications of this breakthrough are far-reaching, offering a potential blueprint for the controlled synthesis of other complex structures previously considered beyond reach.