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Categories: Biology: Cell Biology, Engineering: Biometric
Published Fungal infection in the brain produces changes like those seen in Alzheimer's disease
(via sciencedaily.com) Original source Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and, important for the understanding of Alzheimer's disease development, generates amyloid beta (Ab)-like peptides, toxic protein fragments from the amyloid precursor protein that are considered to be at the center of the development of Alzheimer's disease.
Published Can't stop binging on fries and BBQ?
(via sciencedaily.com) Original source People overeat and become overweight for a variety of reasons. The fact that flavorful high-calorie food is often available nearly everywhere at any time doesn't help. Researchers have determined for the first time why certain chemicals in cooked or processed foods, called advanced glycation end products, or AGEs, increase hunger and test our willpower or ability to make healthy choices when it comes to food.
Published The deep slumber of a hospital pathogen: Why infections with Acinetobacter baumannii can flare up again and again
(via sciencedaily.com) Original source A research team has discovered a fundamental mechanism that helps the dreaded hospital pathogen Acinetobacter baumannii to survive. This mechanism explains why the pathogen is difficult to eradicate in hospitals and why infections flare up again and again in patients: When living conditions become too unfavorable for the bacteria, they fall into a kind of slumber. In this state, conventional diagnostic methods can no longer detect them nor is it possible to kill them off. When living conditions improve again, they awaken from this 'deep sleep'.
Published Peering inside cells to see how they respond to stress
(via sciencedaily.com) Original source The heat shock response of cells is a classic model of biological adaptation, part of the fundamental processes of life -- conserved in creatures from single-celled yeast to humans -- that allow our cells to adjust to changing conditions in their environment. For years, scientists have focused on how different genes respond to heat stress to understand this survival technique. Now, thanks to the innovative use of advanced imaging techniques, researchers are getting an unprecedented look at the inner machinery of cells to see how they respond to heat stress.
Published Climate change coping mechanism discovered in humble algae
(via sciencedaily.com) Original source One of the building blocks of ocean life can adapt to cope with the effects of climate change, according to new research. The discovery holds promises for biotechnology developments that could counter the negative effects of changing environmental conditions, such as ocean warming and even the reduction in the productivity of crops.
Published Fecal microbe transplants: B. vulgatus genes that correlate with early colonization
(via sciencedaily.com) Original source Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants, little was known about which donor strains provide long-term engraftment, and which engraft early after the transplant. Most failures of fecal microbe transplantation occur in the first four weeks. Researchers have now found 19 Bacteroides vulgatus genes that were unique to three strains that show early engraftment in patients after a fecal transplant, as opposed to seven strains that did not show early engraftment.
Published 200-year-old DNA helps map tiny fly's genetic course to new lands, modern times
(via sciencedaily.com) Original source Researchers have extracted and analyzed DNA from fruit flies housed in museum collections in Lund, Stockholm and Copenhagen. Surprisingly, the researchers found the fruit flies collected in Sweden in the early 1800s were more genetically similar to 21st century flies than the Swedish samples from the 1930s.
Published Scientists generate first single-cell 'atlas' of the primate brain to help explore links between molecules, cells, brain function and disease
(via sciencedaily.com) Original source As part of the effort to better understand the evolution of the brains in people and animals, a research team has generated the world's largest primate brain-wide atlas.
Published Scientists unveil detailed cell maps of the human brain and the nonhuman primate brain
(via sciencedaily.com) Original source A group of international scientists have mapped the genetic, cellular, and structural makeup of the human brain and the nonhuman primate brain. This understanding of brain structure allows for a deeper knowledge of the cellular basis of brain function and dysfunction, helping pave the way for a new generation of precision therapeutics for people with mental disorders and other disorders of the brain.
Published Engineered bacteria paint targets on tumors for cancer-killing T cells to see
(via sciencedaily.com) Original source Synthetic biologists report on a new approach to attacking tumors. They have engineered tumor-colonizing bacteria (probiotics) to produce synthetic targets in tumors that direct CAR-T cells to destroy the newly highlighted cancer cells.
Published Honey bees may inherit altruistic behavior from their mothers
(via sciencedaily.com) Original source True altruism is rare behavior in animals, but a new study has found that honey bees display this trait. Additionally, they found that an evolutionary battle of genetics may determine the parent they inherit it from.
Published Win-win in muscle research: Faster results and fewer laboratory animals thanks to new method
(via sciencedaily.com) Original source To study muscle diseases, scientists rely on the mouse as a model organism. Researchers have now developed a new method that is not only faster and more efficient than conventional ones but also greatly reduces the number of experimental animals needed for studying the function of genes in muscle fibers.
Published Experts warn of risk of civil unrest in UK due to food shortages
(via sciencedaily.com) Original source Food shortages caused by extreme weather could lead to civil unrest in the UK, according to a new study which has surveyed some of the country’s leading food experts.
Published Omega-3 discovery moves us closer to 'precision nutrition' for better health
(via sciencedaily.com) Original source Researchers have obtained new insights into how African-American and Hispanic-American people’s genes influence their ability to use Omega-3 and Omega-6 fatty acids for good health. The findings are an important step toward “precision nutrition” – where a diet tailored to exactly what our bodies need can help us live longer, healthier lives.
Published Remains of artificial turf is an important source of pollution of the aquatic environment
(via sciencedaily.com) Original source Every year, around 1,200 and 1,400 artificial turf sports fields are installed in the European Union. These fields are made up of synthetic fibers, mainly plastics, that mimic the appearance of natural grass. Recently, scientists conducted a study that characterizes and quantifies the presence of artificial turf fibers in samples collected from surface waters of the Catalan coast and the Guadalquivir River. The findings indicate that artificial turfs can be an important source of pollution in the aquatic environment, accounting for up to 15% of the plastics larger than 5 mm in length that are found floating in the aquatic environment.
Published Using different flours for sourdough fosters different bacteria -- and flavors
(via sciencedaily.com) Original source A new study of the microbial ecosystem in sourdough finds that using different types of flour fosters distinct bacterial communities, and that these differences contribute to the variation of sourdough aromas and flavors.
Published An AI tool that can help forecast viral outbreaks
(via sciencedaily.com) Original source EVEscape predicts future viral mutations, new variants using evolutionary, biological information.
Published Doubling down on known protein families
(via sciencedaily.com) Original source A massive computational analysis of microbiome datasets has more than doubled the number of known protein families. This is the first time protein structures have been used to help characterize the vast array of microbial 'dark matter.'
Published Mummified feces reveals pre-Columbian cultures of the Caribbean consumed a diversity of plants
(via sciencedaily.com) Original source DNA analysis of mummified feces reveals two pre-Columbian Caribbean cultures ate a wide variety of plants, like maize, sweet potato, and peanuts -- and tobacco and cotton traces were detected too, according to a new study.
Published Evolutionary secrets of 'Old Tom' and the killer whales of Eden revealed by genetic study
(via sciencedaily.com) Original source Evolutionary biologists have for the first time decoded the genetic lineage of a famous killer whale and a pod that once worked alongside whale hunters off the coast of Australia. In the Australian tradition of claiming New Zealand's celebrities as its own, Old Tom, the leader of a pod of killer whales that famously helped whalers hunt baleen whales in the 20th century, has ancestral links to modern-day killer whales in New Zealand, according to new DNA research. Old Tom also shared a common ancestor with killer whales from Australasia, the North Pacific, and North Atlantic Oceans, but is most similar to modern New Zealand killer whales. However, most of Tom's DNA code is not found in other killer whales globally suggesting that the killer whales of Eden may have become extinct locally.