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Categories: Biology: Cell Biology, Engineering: Biometric
Published Same genes behind heart muscle disorders in humans and Dobermanns
(via sciencedaily.com) Original source Researchers have made a significant finding in determining the genetic background of dilated cardiomyopathy in Dobermanns. This research helps us understand the genetic risk factors related to fatal diseases of the heart muscle and the mechanisms underlying the disease, and offers new tools for their prevention.
Published Conversations with plants: Can we provide plants with advance warning of impending dangers?
(via sciencedaily.com) Original source Plant scientists have engineered a light-controlled gene expression system (optogenetics system) from a prokaryotic system into a eukaryotic system that is tailored for plants.
Published This parasitic plant convinces hosts to grow into its own flesh--it's also an extreme example of genome shrinkage
(via sciencedaily.com) Original source Balanophora shed one third of its genes as it evolved into a streamlined parasitic plant -- an extreme degree of genome shrinkage even among parasites. Along the way this subtropical plant developed the ability to induce the host plant to grow into the parasite's own flesh -- forming chimeric organs that mix host and parasite tissues.
Published Dinosaur feathers reveal traces of ancient proteins
(via sciencedaily.com) Original source Palaeontologists have discovered X-ray evidence of proteins in fossil feathers that sheds new light on feather evolution.
Published Researchers develop first method to study microRNA activity in single cells
(via sciencedaily.com) Researchers have developed the first method to uncover the tasks that microRNAs perform in single cells. This is a huge improvement over existing state-of-the-art methods that require millions of cells and will for the first time allow researchers to study microRNAs in complex tissues such as brains.
Published Nanoparticles made from plant viruses could be farmers' new ally in pest control
(via sciencedaily.com) Engineers have devised a new solution to control a major agricultural menace, root-damaging nematodes. Using plant viruses, the researchers created nanoparticles that can deliver pesticide molecules to previously inaccessible depths in the soil. This 'precision farming' approach could potentially minimize environmental toxicity and cut costs for farmers.
Published Split gene-editing tool offers greater precision
(via sciencedaily.com) To make a gene-editing tool more precise and easier to control, engineers split it into two pieces that only come back together when a third molecule is added.
Published Scientists regenerate neurons that restore walking in mice after paralysis from spinal cord injury
(via sciencedaily.com) Original source In a new study in mice, researchers have uncovered a crucial component for restoring functional activity after spinal cord injury. The neuroscientists have shown that re-growing specific neurons back to their natural target regions led to recovery, while random regrowth was not effective.
Published Unzipping mRNA rallies plant cells to fight infection
(via sciencedaily.com) Original source Living things from plants to humans must constantly adjust the chemical soup of proteins -- the workhorse molecules of life -- inside their cells to adapt to stress or changing conditions. Now, researchers have identified a previously unknown molecular mechanism that helps explain how they do it. A team now reveals hairpin-like structures of mRNA that, by zipping and unzipping, help cells change the mix of proteins they produce when under stress.
Published Exercise and muscle regulation: Implications for diabetes and obesity
(via sciencedaily.com) Original source How do our muscles respond at the molecular level to exercise? Researchers have unraveled the cellular basis and signaling pathways responsible for the positive impact of physical activity on our overall health. Regulatory T cells, a type of immune cell, play a critical role in ensuring proper muscle function. These novel insights are paving the path towards precision medicines targeting metabolic disorders like obesity and diabetes, as well as muscle-related illnesses.
Published Genetically modifying individual cells in animals
(via sciencedaily.com) Original source Researchers have developed a method that lets them genetically modify each cell differently in animals. This allows them to study in a single experiment what used to require many animal experiments. Using the new method, the researchers have discovered genes that are relevant for a severe rare genetic disorder.
Published Artificial Intelligence tools shed light on millions of proteins
(via sciencedaily.com) Original source A research team has uncovered a treasure trove of uncharacterized proteins. Embracing the recent deep learning revolution, they discovered hundreds of new protein families and even a novel predicted protein fold.
Published Sometimes beneficial, sometimes damaging: The double role of the enzyme chameau
(via sciencedaily.com) Original source Biologists have discovered why an enzyme is important for the survival of fruit flies, even though it can shorten their lives under certain conditions.
Published Plant and forest researchers do not 'anthropomorphize' plants
(via sciencedaily.com) Original source Plants are often attributed with abilities similar to those known in the animal or human world. Trees are said to have feelings and can therefore care for their offspring, like mothers. Researchers analyzed the claims in two popular publications on forests and reached the conclusion that conjecture is equated with fact. They warn against 'anthropomorphizing' plants.
Published A newly identified virus emerges from the deep
(via sciencedaily.com) Original source Marine virologists analyzed sediment from the Mariana Trench, the deepest place on Earth, and identified a new bacteriophage.
Published Spider silk is spun by silkworms for the first time, offering a green alternative to synthetic fibers
(via sciencedaily.com) Scientists have synthesized spider silk from genetically modified silkworms, producing fibers six times tougher than the Kevlar used in bulletproof vests. The study is the first to successfully produce full-length spider silk proteins using silkworms. The findings demonstrate a technique that could be used to manufacture an environmentally friendly alternative to synthetic commercial fibers such as nylon.
Published Newfound brain circuit explains why infant cries prompt milk release
(via sciencedaily.com) Original source Hearing the sound of a newborn's wail can trigger the release of oxytocin, a brain chemical that controls breast-milk release in mothers, a new study in rodents shows. Researchers found that once prompted, this flood of hormones continues for roughly five minutes before tapering off, enabling mothers to feed their young until they are sated or begin crying again.
Published Imaging the smallest atoms provides insights into an enzyme's unusual biochemistry
(via sciencedaily.com) A team has used neutron crystallography to image all of the atoms in a radical intermediate of a copper amine oxidase enzyme. They disclosed previously unknown details, such as precise conformational changes, that help to explain the enzyme's biochemistry. This work might help researchers engineer enzymes that facilitate unusual chemistry or are highly efficient at room temperature that are useful in chemical industry.
Published Fast-track strain engineering for speedy biomanufacturing
(via sciencedaily.com) Using engineered microbes as microscopic factories has given the world steady sources of life-saving drugs, revolutionized the food industry, and allowed us to make sustainable versions of valuable chemicals previously made from petroleum. But behind each biomanufactured product on the market today is the investment of years of work and many millions of dollars in research and development funding. Scientists want to help the burgeoning industry reach new heights by accelerating and streamlining the process of engineering microbes to produce important compounds with commercial-ready efficiency.
Published Yogurt may be the next go-to garlic breath remedy
(via sciencedaily.com) Original source A new study conducted in a lab -- with follow-up human breath tests being planned -- showed that whole milk plain yogurt prevented almost all of the volatile compounds responsible for garlic's pungent scent from escaping into the air.