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Categories: Biology: Cell Biology, Engineering: Biometric
Published AI could run a million microbial experiments per year



Automation uncovers combinations of amino acids that feed two bacterial species and could tell us much more about the 90% of bacteria that humans have hardly studied. An artificial intelligence system enables robots to conduct autonomous scientific experiments -- as many as 10,000 per day -- potentially driving a drastic leap forward in the pace of discovery in areas from medicine to agriculture to environmental science.
Published Gutless marine worms on a Mediterranean diet: Animals can synthesize phytosterols



Phytosterols are good for your health, but humans and other animals are not able to make them themselves, only plants can. To acquire phytosterols, humans are increasingly turning to supplements, green smoothies, or a Mediterranean diet with plenty of plant-based foods. Researchers have now discovered that tiny gutless worms from the Mediterranean can synthesize phytosterols on their own. Their study provides evidence that many other animals also have the genes needed to make their own phytosterols.
Published Alternative 'fuel' for string-shaped motors in cells



Researchers discover a unique two-component molecular motor that uses a kind of renewable chemical energy to pull vesicles toward membrane-bound organelles.
Published Biofortification of microgreens with zinc could mitigate global 'hidden hunger'



When the seeds of plants such as pea and sunflower are biofortified with zinc, the seedlings they quickly produce -- harvested as microgreens -- could both help to mitigate global malnutrition and boost the odds of people surviving a catastrophe.
Published Happy worms have healthy eggs



Researchers have exposed roundworms (a well-established model organism in biological research) to selective serotonin reuptake inhibitors (SSRIs), a class of drugs used for treating depression and anxiety. Surprisingly, this treatment improved the quality of aging females' egg cells.
Published Scientists discover the dynamics of an 'extra' chromosome in fruit flies



Most chromosomes have been around for millions of years. Now, researchers have revealed the dynamics of a new, very young chromosome in fruit flies that is similar to chromosomes that arise in humans and is associated with treatment-resistant cancer and infertility. The findings may one day lead to developing more targeted therapies for treating these conditions.
Published Scientists recover an ancient woman's DNA from a 20,000-year-old pendant



An international research team has for the first time successfully isolated ancient human DNA from a Paleolithic artefact: a pierced deer tooth discovered in Denisova Cave in southern Siberia. To preserve the integrity of the artefact, they developed a new, nondestructive method for isolating DNA from ancient bones and teeth. From the DNA retrieved they were able to reconstruct a precise genetic profile of the woman who used or wore the pendant, as well as of the deer from which the tooth was taken. Genetic dates obtained for the DNA from both the woman and the deer show that the pendant was made between 19,000 and 25,000 years ago. The tooth remains fully intact after analysis, providing testimony to a new era in ancient DNA research, in which it may become possible to directly identify the users of ornaments and tools produced in the deep past.
Published New tusk-analysis techniques reveal surging testosterone in male woolly mammoths



Traces of sex hormones extracted from a woolly mammoth's tusk provide the first direct evidence that adult males experienced musth, a testosterone-driven episode of heightened aggression against rival males, according to a new study.
Published Single-molecule valve: Breakthrough in nanoscale control



A research group has succeeded in regulating the flow of single molecules in solution by opening and closing the nanovalve mounted on the nanofluidic device by applying external pressure. The research group fabricated a device with a ribbon-like, thin, soft glass sheet on the top, and at the bottom a hard glass substrate having nanochannels and nanovalve seats. By applying external pressure to the soft glass sheet to open and close the valve, they succeeded in directly manipulating and controlling the flow of individual molecules in solution. They also observed an effect of fluorescence signal amplification when single fluorescent molecules are confined in the tiny nanospace inside the valve. The effect can be ascribed to the nanoconfinement, which suppresses the random motion of the molecules.
Published A novel stem cell adhesive using mussels



A team of researchers develops stem cell adhesive for arthritis treatment using mussel adhesion protein and hyaluronic acid.
Published New RNA-seq, metabolomics protocol offers more efficient extraction that maintains data integrity



Scientists have developed a new extraction protocol for RNA-seq and metabolomic analysis, offering a more complete picture of cellular activity than either technique on its own. The protocol employs a streamlined extraction from a single sample, which reduces variation, improves efficiency, preserves data fidelity and maximizes use of precious biospecimens.
Published Scientists present evidence for a billion-years arms race between viruses and their hosts



Researchers have proposed a new evolutionary model for the origin of a kingdom of viruses called Bamfordvirae, suggesting a billion-years evolutionary arms race between two groups within this kingdom and their hosts.
Published Wiggly proteins guard the genome



Dynamic network in the pores of the nuclear envelope blocks dangerous invaders.
Published Do people and monkeys see colors the same way?



New findings in color vision research imply that humans can perceive a greater range of blue tones than monkeys do. Distinct connections found in the human retina may indicate recent evolutionary adaptations for sending enhanced color vision signals from the eye to the brain.
Published New mechanisms regulating plant response to temperature



Discovery of a new protein complex helps scientists understand how plants interpret changes in temperature over time
Published Herpes study adds to understanding of viral reinfections, how to potentially prevent them



A new study on herpes infections of the eye helps shed light on the question of viral reinfections by identifying a key protein involved in viral reinfections that could be targeted by antiviral drugs.
Published Previously unknown intercellular electricity may power biology



Researchers have discovered that the electrical fields and activity that exist through a cell's membrane also exist within and around another type of cellular structure called biological condensates. Like oil droplets floating in water, these structures exist because of differences in density. Their foundational discovery could change the way researchers think about biological chemistry. It could also provide a clue as to how the first life on Earth harnessed the energy needed to arise.
Published New research redefines mammalian tree of life



Scientists from around the globe are using the largest mammalian genomic dataset in history to determine the evolutionary history of the human genome in the context of mammalian evolutionary history. Their ultimate goal is to better identify the genetic basis for traits and diseases in people and other species.
Published Artificial photosynthesis for environmentally friendly food production



Ensuring the supply of food to the constantly growing world population and protecting the environment at the same time are often conflicting objectives. Now researchers have successfully developed a method for the synthetic manufacture of a nutritional protein using a type of artificial photosynthesis. The animal feed industry is the primary driver of high demand for large volumes of this nutritional protein L-alanine, which is also suitable for use in meat substitute products.
Published Scientists identify antivirals that could combat emerging infectious diseases



A new study has identified potential broad-spectrum antiviral agents that can target multiple families of RNA viruses that continue to pose a significant threat for future pandemics.