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Categories: Biology: Cell Biology, Engineering: Biometric
Published Fasting primes the immune system's natural killer cells to better fight cancer, new study in mice finds
(via sciencedaily.com) Original source A team of researchers has shown for the first time that fasting can reprogram the metabolism of natural killer cells, helping them to survive in the harsh environment in and around tumors, while also improving their cancer-fighting ability.
Published Infectious H5N1 influenza virus in raw milk rapidly declines with heat treatment
(via sciencedaily.com) Original source The amount of infectious H5N1 influenza viruses in raw milk rapidly declined with heat treatment in laboratory research. However, small, detectable amounts of infectious virus remained in raw milk samples with high virus levels when treated at 72 degrees Celsius (161.6 degrees Fahrenheit) for 15 seconds -- one of the standard pasteurization methods used by the dairy industry. The authors of the study stress, however, that their findings reflect experimental conditions in a laboratory setting and are not identical to large-scale industrial pasteurization processes for raw milk.
Published Scientists preserve DNA in an amber-like polymer
(via sciencedaily.com) Original source With their 'T-REX' method, researchers developed a glassy, amber-like polymer that can be used for long-term storage of DNA, such as entire human genomes or digital files such as photos.
Published Only one in 20 therapies tested in animals reach approval for human use
(via sciencedaily.com) Original source An analysis of reviews of translational biomedical research reveals that just 5% of therapies tested in animals reach regulatory approval for human use. The umbrella review summarizes other systematic reviews and provides high level evidence that while the rate of translation to human studies is 50%, there is steep drop off before final approval.
Published Modifying genomes of tardigrades to unravel their secrets
(via sciencedaily.com) Original source Some species of tardigrades are highly and unusually resilient to various extreme conditions fatal to most other forms of life. The genetic basis for these exceptional abilities remains elusive. Researchers have now successfully edited genes using the CRISPR technique in a highly resilient tardigrade species previously impossible to study with genome-editing tools. The successful delivery of CRISPR to an asexual tardigrade species directly produces gene-edited offspring. The design and editing of specific tardigrade genes allow researchers to investigate which are responsible for tardigrade resilience and how such resilience can work.
Published Putting the brakes on chronic inflammation
(via sciencedaily.com) Original source Scientists have discovered a previously unknown link between two key pathways that regulate the immune system in mammals -- a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD). This family of disorders severely impacts the health and quality of life of more than 2 million people in the United States.
Published The gender gap in life expectancy: Are eggs and sperm partly responsible?
(via sciencedaily.com) Original source Researchers have found that germ cells, which develop into eggs and sperm, drive sex-dependent differences in lifespan in vertebrates. Female and male germ cells increase and reduce lifespan, respectively. These effects are controlled via estrogen and growth factor hormones in females and vitamin D in males. Vitamin D supplementation extends lifespan in both males and females. The results clarify the link between reproduction and aging and show that vitamin D may improve longevity in vertebrates.
Published Are plants intelligent? It depends on the definition
(via sciencedaily.com) Original source Goldenrod can perceive other plants nearby without ever touching them, by sensing far-red light ratios reflected off leaves. When goldenrod is eaten by herbivores, it adapts its response based on whether or not another plant is nearby. Is this kind of flexible, real-time, adaptive response a sign of intelligence in plants?
Published Study shows role of fathers in seeding the microbiota of newborns and confirms benefits of maternal fecal microbiota transplants
(via sciencedaily.com) Original source A mother's contribution to the makeup of a newborn baby's microbiota has been well documented. Now a new article shows the important contributions that fathers make to the composition of microorganisms colonizing a baby's gut as well. Furthermore, the study confirmed that maternal fecal microbiota transfer (FMT) in babies born by caesarean section can help to correct the microbiota disturbances often observed in babies who are not born vaginally.
Published New technique reveals earliest signs of genetic mutations
(via sciencedaily.com) Original source Mutations are changes in the molecular 'letters' that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including cancer. Now, a new study introduces an original technique, called HiDEF-seq, that can accurately detect the early molecular changes in DNA code that precede mutations.
Published Scientists engineer yellow-seeded camelina with high oil output
(via sciencedaily.com) Original source Using tools of modern genetics, plant biochemists have produced a new high-yielding oilseed crop variety -- a yellow-seeded variety of Camelina sativa, a close relative of canola, that accumulates 21.4% more oil than ordinary camelina.
Published Soil bacteria respire more CO2 after sugar-free meals
(via sciencedaily.com) Original source Researchers tracked how plant matter moves through bacteria's metabolism. Microbes respire three times as much carbon dioxide (CO2) from non-sugar carbons from lignin compared to sugar from cellulose. Although microbes consume both types of plant matter at the same time, each type enters a different metabolic pathway. Findings could improve predictions of how climate-dependent changes in soil carbon types will affect microbial CO2 production.
Published Virus-like nanoparticles control the multicellular organization and reproduction of host bacteria
(via sciencedaily.com) Original source Researchers have discovered that virus-like nanoparticles can promote the multicellular organization and reproduction of host bacteria. These particles, which are evolutionarily related to phages (viruses that infect bacteria), contain an enzyme that helps shape the multicellular architecture and ultimately enhances morphological differentiation.
Published Algae offer real potential as a renewable electricity source
(via sciencedaily.com) Original source The need to transition away from fossil fuels to more sustainable energy production is critical. That's why a team of researchers is looking at a potential power source that not only produces no carbon emissions but removes carbon as it works: algae.
Published Scientists unlock secrets of how archaea, the third domain of life, makes energy
(via sciencedaily.com) Original source An international scientific team has redefined our understanding of archaea, a microbial ancestor to humans from two billion years ago, by showing how they use hydrogen gas. The findings explain how these tiny lifeforms make energy by consuming and producing hydrogen. This simple but dependable strategy has allowed them to thrive in some of Earth's most hostile environments for billions of years.
Published Breakthrough in creating cyclic peptide opens the way for new antibiotics
(via sciencedaily.com) Original source A discovery could speed up efforts to produce new antibiotics in the fight against antimicrobial resistance.
Published Protein study could help researchers develop new antibiotics
(via sciencedaily.com) Original source A team has found a way to make the bacterial enzyme histidine kinase water-soluble, which could make it possible to rapidly screen potential antibiotics that might interfere with its functions.
Published How human derived RNA fragments help the Hepatitis E virus
(via sciencedaily.com) Original source Why does Hepatitis E become chronic in some patients, and why do medications not work? To find out, an international research team led by scientists from Bochum observed a patient with chronic Hepatitis E infection over a year. Repeated sequencing of the virus RNA showed that the virus incorporated various parts of the host's messenger RNA into its genome. This resulted in a replication advantage, which may have contributed to the infection becoming chronic.
Published Gut microbes from aged mice induce inflammation in young mice, study finds
(via sciencedaily.com) Original source When scientists transplanted the gut microbes of aged mice into young 'germ-free' mice -- raised to have no gut microbes of their own -- the recipient mice experienced an increase in inflammation that parallels inflammatory processes associated with aging in humans. Young germ-free mice transplanted with microbes from other young mice had no such increase.
Published A protein that enables smell--and stops cell death
(via sciencedaily.com) Original source While smell plays a considerable role in the social interactions of humans -- for instance, signaling fear or generating closeness -- for ants, it is vitally important. Researchers have found that a key protein named Orco, essential for the function of olfactory cells, is also critical for the cells' survival in ants.