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Categories: Biology: Cell Biology, Engineering: Graphene
Published Ancient DNA reveals how a chicken virus evolved to become more deadly
(via sciencedaily.com) Original source An international team of scientists led by geneticists and disease biologists has used ancient DNA to trace the evolution of Marek's Disease Virus (MDV). This global pathogen causes fatal infections in unvaccinated chickens and costs the poultry industry over $1 billion per year. The findings show how viruses evolve to become more virulent and could lead to the development of better ways to treat viral infections.
Published Diverse gut bacteria communities protect against harmful pathogens by nutrient blocking
(via sciencedaily.com) Original source New study demonstrates that diverse communities of resident bacteria can protect the human gut from disease-causing microorganisms. However, this protective effect is lost when only single species of gut bacteria are present. The researchers found that protective communities block the growth of harmful pathogens by consuming nutrients that the pathogen needs.
Published Opportunities to improve future HIV vaccine candidates
(via sciencedaily.com) Original source An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study. The study findings draw comparisons between the immune system activity of past HIV vaccine study participants and people with HIV who naturally keep the virus from replicating even in the absence of antiretroviral therapy (ART). The latter individuals are often called 'long-term non-progressors' or 'elite controllers' (LTNPs/ECs).
Published Can you change a chicken into a frog, a fish or a chameleon?
(via sciencedaily.com) Original source Researchers have developed a theoretical framework that can reproduce and predict the patterns associated with gastrulation in a chicken embryo.
Published How the immune system fights to keep herpes at bay
(via sciencedaily.com) Original source In a study of lab-engineered cells, researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction. The findings could inform the design of new treatments for herpes and other viruses that replicate in the same way.
Published New understanding of ancient genetic parasite may spur medical breakthroughs
(via sciencedaily.com) Original source Researchers have determined the structure of the most common material in our genomes. New treatments for autoimmune diseases, cancer and neurodegeneration may follow.
Published Gut bacteria of malnourished children benefit from key elements in therapeutic food
(via sciencedaily.com) Original source New research has identified key, naturally occurring biochemical components of a novel therapeutic food that is aimed at repairing malnourished children's underdeveloped gut microbiomes. The study also has identified the important bacterial strains that process these biochemical components. The findings may help guide treatment with a current food formulation and enable creation of new, more effective formulations in the future.
Published Enzymes can't tell artificial DNA from the real thing
(via sciencedaily.com) Original source Researchers have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.
Published Scientists unveil complete cell map of a whole mammalian brain
(via sciencedaily.com) Original source Researchers have created a complete cell atlas of a whole mammalian brain. This atlas serves as a map for the mouse brain, describing the type, location, and molecular information of more than 32 million cells and providing information on connectivity between these cells.
Published Nanoprobe with a barcode
(via sciencedaily.com) Original source Protein-splitting enzymes play an important role in many physiological processes. Such proteases are generally present in an inactive state, only becoming activated under certain conditions. Some are linked to diseases like infections or cancer, making it important to have methods that can selectively detect active proteases. Scientists have introduced a new class of protease-activity sensors: gold nanoparticles equipped with peptide DNA.
Published Cells move in groups differently than they do when alone
(via sciencedaily.com) Original source A protein that helps generate the force needed for single cells to move works differently in cells moving in groups, a new study shows.
Published Mice possess natural gene therapy system
(via sciencedaily.com) Original source A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.
Published Cell types in the eye have ancient evolutionary origins
(via sciencedaily.com) Original source In a comparative analysis across vertebrates of the many cell types in the retina -- mice alone have 130 types -- researchers concluded that most cell types have an ancient evolutionary history. Their remarkable conservation across species suggests that the retina of the last common ancestor of all mammals, which roamed the earth some 200 million year ago, must have had a complexity rivaling the retina of modern mammals.
Published A rare enzyme role change with bacterial defense system assembly
(via sciencedaily.com) Original source Scientists have revealed a never-before-seen phenomenon in a protein: Alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.
Published A sugar analysis could reveal different types of cancer
(via sciencedaily.com) Original source In the future, a little saliva may be enough to detect an incipient cancer. Researchers have developed an effective way to interpret the changes in sugar molecules that occur in cancer cells.
Published A new brew: Evaluating the flavor of roasted, lab-grown coffee cells
(via sciencedaily.com) Original source It may soon be time to wake up and smell the lab-grown coffee made from cultured plant cells. But it's not clear whether drinks from this product replicate coffee beans' complex flavors. Now, a study found that some of the comforting aromas and tastes of a conventional cup of coffee could be reproduced by roasting and brewing coffee cell cultures.
Published Underwater architects: The 'burrowing effect' of foraminifera on marine environments
(via sciencedaily.com) Original source Impact of single-cell organisms on sediment oxygen levels and bacterial diversity measured for the first time.
Published Extremely rare bird captured on film
(via sciencedaily.com) Original source A striking and extremely rare half-female, half-male bird has been spotted by a zoologist.
Published Clinical trial demonstrates that the ketogenic diet is effective at controlling polycystic kidney disease
(via sciencedaily.com) Original source It's official: The ketogenic diet proved to be effective at controlling polycystic kidney disease (PKD) in the first randomized controlled clinical trial of ketogenic metabolic therapy for PKD.
Published Zika's shape-shifting machinery, and a possible vulnerability
(via sciencedaily.com) Original source Viruses have limited genetic material -- and few proteins -- so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins. Now researchers have shown how the virus does so much with so little and may have identified a therapeutic vulnerability.