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Categories: Biology: Cell Biology, Engineering: Graphene
Published Link between high levels of niacin -- a common B vitamin -- and heart disease, study suggests
(via sciencedaily.com) Original source Researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease. Higher circulating levels of 4PY were strongly associated with development of heart attack, stroke and other adverse cardiac events in large-scale clinical studies. The researchers also showed in preclinical studies that 4PY directly triggers vascular inflammation which damages blood vessels and can lead to atherosclerosis over time.
Published Toxoplasmosis: Evolution of infection machinery
(via sciencedaily.com) Original source Researchers have identified a protein that evolved concurrently with the emergence of cellular compartments crucial for the multiplication of the toxoplasmosis pathogen.
Published First human trial shows 'wonder' material can be developed safely
(via sciencedaily.com) Original source A revolutionary nanomaterial with huge potential to tackle multiple global challenges could be developed further without acute risk to human health, research suggests.
Published Superbug killer: New synthetic molecule highly effective against drug-resistant bacteria
(via sciencedaily.com) Original source A new antibiotic overcomes antimicrobial resistance mechanisms that have rendered many modern drugs ineffective and are driving a global public health crisis.
Published Two-dimensional waveguides discovered
(via sciencedaily.com) Original source Scientists announce the discovery of slab waveguides based on the two-dimensional material hexagonal boron nitride.
Published Big new idea introduced with the help of tiny plankton
(via sciencedaily.com) Original source A new model bridges the rules of life at the individual scale and the ecosystem level, which could open new avenues of exploration in ecology, global change biology, and ultimately ecosystem management.
Published Do sugar-free candy and gum give you gas? Researchers think they know why
(via sciencedaily.com) Original source Scientists may have figured out why some people have trouble digesting sorbitol, a sugar alcohol used in sugar-free gum, mints, candy and other products.
Published Asexual propagation of crop plants gets closer
(via sciencedaily.com) Original source When the female gametes in plants become fertilized, a signal from the sperm activates cell division, leading to the formation of new plant seeds. This activation can also be deliberately triggered without fertilization, as researchers have shown. Their findings open up new avenues for the asexual propagation of crop plants.
Published Protein-rich breakfast boosts satiety and concentration
(via sciencedaily.com) Original source A new study has explored the link between diet and cognitive function, and the results reveal that a protein-rich breakfast can increase satiety and improve concentration. This is important knowledge in a society with increasing obesity rates and lifestyle-related diseases.
Published Root microbes may be the secret to a better tasting cup of tea
(via sciencedaily.com) Original source You'd think the complex flavor in a quality cup of tea would depend mainly on the tea varieties used to make it. But a new study shows that the making of a delicious cup of tea depends on another key ingredient: the collection of microbes found on tea roots. By altering that assemblage, the authors showed that they could make good-quality tea even better.
Published Ancient retroviruses played a key role in the evolution of vertebrate brains
(via sciencedaily.com) Original source Researchers report that ancient viruses may be to thank for myelin -- and, by extension, our large, complex brains. The team found that a retrovirus-derived genetic element or 'retrotransposon' is essential for myelin production in mammals, amphibians, and fish. The gene sequence, which they dubbed 'RetroMyelin,' is likely a result of ancient viral infection, and comparisons of RetroMyelin in mammals, amphibians, and fish suggest that retroviral infection and genome-invasion events occurred separately in each of these groups.
Published Team creates novel rabies viral vectors for neural circuit mapping
(via sciencedaily.com) Original source A research team has created 20 new recombinant rabies viral vectors for neural circuit mapping that offer a range of significant advantages over existing tools, including the ability to detect microstructural changes in models of aging and Alzheimer's disease brain neurons.
Published Key genes linked to DNA damage and human disease uncovered
(via sciencedaily.com) Original source Scientists unveil 145 genes vital for genome health, and possible strategies to curb progression of human genomic disorders.
Published Researchers uncover mechanisms behind enigmatic shapes of nuclei
(via sciencedaily.com) Original source White blood cells known as neutrophils feature a nucleus that is structured strikingly different than most nuclei. These unique shapes permit neutrophils to travel all over the body to combat invading pathogens. Scientists have now deciphered the shapeshifting puzzle of the neutrophil nucleus.
Published Microscopy: Overcoming the traditional resolution limit for the fast co-tracking of molecules
(via sciencedaily.com) Original source Researchers have developed an innovative method to simultaneously track rapid dynamic processes of multiple molecules at the molecular scale.
Published Pesticides to help protect seeds can adversely affect earthworms' health
(via sciencedaily.com) Original source While pesticides protect crops from hungry animals, pesky insects, or even microbial infections, they also impact other vital organisms, including bees and earthworms. And today, research reveals that worms are affected by the relatively small amounts of chemicals that can leach out of pesticide-treated seeds. Exposure to nonlethal amounts of these insecticides and fungicides resulted in poor weight gain and mitochondrial DNA (mtDNA) damage in the worms.
Published New understanding of avian eggshell attachment -- implications for medical procedures and egg industry
(via sciencedaily.com) Original source Athletes often suffer injuries to ligaments in their knees, particularly to the anterior cruciate ligament or ACL. While surgery to replace these torn ligaments is becoming increasingly common around the world it often needs to be repeated. That's because it has proved challenging to anchor fibrous, soft and wet ligament grafting material into hard bone. Now, researchers have new information from the eggshell membrane in chicken eggs that could help change this picture thanks to the potential it offers for improvements in tissue engineering and biomaterial grafts. Their findings also have the potential to reduce losses for commercial egg and poultry producers.
Published By growing animal cells in rice grains, scientists dish up hybrid food
(via sciencedaily.com) Original source From lab-grown chicken to cricket-derived protein, these innovative alternatives offer hope for a planet struggling with the environmental and ethical impacts of industrial agriculture. Now, scientists add a new recipe to the list -- cultured beef rice -- by growing animal muscle and fat cells inside rice grains. The method results in a nutritious and flavorful hybrid food that, once commercialized, could offer a more affordable protein alternative with a smaller carbon footprint.
Published Controlling root growth direction could help save crops and mitigate climate change
(via sciencedaily.com) Original source Scientists have determined how the well-known plant hormone ethylene is crucial in controlling the angle at which roots grow. The findings can be used to engineer plants and crops that withstand the environmental stresses of climate change and drought, and perhaps to create plants that remove carbon dioxide from the atmosphere and store it deep underground to help mitigate climate change.
Published Nanoparticles that can light up the lymph node cancer cells otherwise undetectable by MRI
(via sciencedaily.com) Original source Researchers have developed a new nanoparticle that can 'hitch a ride' on immune cells, or monocytes. Because of its tiny size, the particle can tag along directly into lymph nodes and help metastasis show up on MRIs where it would otherwise be too hard to detect. The process offers game-changing benefits for the early detection of cancer metastasis in the lymph nodes. While previously, metastasis could only be assessed by an increase in lymph node size; the new particles could lead to MRI contrast agents that can highlight metastatic cells in lymph nodes that may otherwise appear normal.