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Categories: Biology: Cell Biology, Engineering: Graphene
Published How leafcutter ants cultivate a fungal garden to degrade plants and provide insights into future biofuels
(via sciencedaily.com) Original source Scientists developed a new method to map exactly how a fungus works with leafcutter ants in a complex microbial community to degrade plant material at the molecular level. The team's insights are important for biofuels development.
Published Disrupted cellular function behind type 2 diabetes in obesity
(via sciencedaily.com) Original source Disrupted function of 'cleaning cells' in the body may help to explain why some people with obesity develop type 2 diabetes, while others do not. A study describes this newly discovered mechanism.
Published A clutch stretch goes a long way
(via sciencedaily.com) Original source New results reveal a new mode of force transmission in which dynamic molecular stretching bridges the extracellular matrix and flowing F-actin moving at different speeds. This discovery underscores the necessity of molecular elasticity and random coupling for sufficiently transmitting force. The findings also call for revising the role of molecular unfolding.
Published The arrangement of bacteria in biofilms affects their sensitivity to antibiotics
(via sciencedaily.com) Original source Many bacteria form an antibiotic-resistant slime. Research detailing that slime's structure could help lead to new treatments.
Published Active components of ginkgo biloba may improve early cognitive recovery after stroke
(via sciencedaily.com) Original source Adults treated with 14 days of intravenous injections of ginkgo diterpene lactone meglumine (GDLM) -- a combination of biologically active components of ginkgo biloba -- after an ischemic (clot-caused) stroke had better cognitive recovery at 14 days and 90 days.
Published Resistant bacteria can remain in the body for years
(via sciencedaily.com) Original source Fighting disease-causing bacteria becomes more difficult when antibiotics stop working. People with pre-existing conditions in particular can carry resistant germs and suffer from repeated infections for years, according to a new study.
Published Plant receptors that control immunity and development share a common origin
(via sciencedaily.com) Original source Researchers have traced the origin and evolutionary trajectory of plant immune receptors. Their discovery will make it easier to identify immune receptor genes from genomic information and could help in the development of pathogen-resistant crops.
Published Gut bacteria can process dietary fiber into an anti-allergy weapon
(via sciencedaily.com) Original source Short-chain fatty acids (SCFAs), which are produced by gut bacteria from dietary fiber, regulate our immune system, but the mechanism of their action remains unknown. In a recent study, researchers investigated how SCFAs interact with mast cells, a type of white blood cell that plays a central role in allergic reactions. Their findings and insights could lead to innovative and effective anti-allergy medications, supplements, and diets, paving the way for healthier lives.
Published Key dynamics of 2D nanomaterials: View to larger-scale production
(via sciencedaily.com) Original source A team of researchers mapped out how flecks of 2D materials move in liquid -- knowledge that could help scientists assemble macroscopic-scale materials with the same useful properties as their 2D counterparts.
Published Mussel-inspired antimicrobial coating protects sanitary fabrics from infections
(via sciencedaily.com) Original source Researchers have developed an innovative material to fight against the spread of pathogens, infections and antimicrobial resistance. Inspired by the substances secreted by mussels to adhere to rocks, it can be used as a coating to protect healthcare fabrics and provides an effective alternative to commonly used materials such as paper, cotton, surgical masks and commercial plasters.
Published LSH genes associated with defining the shapes of stems, flowers and leaves required for N-fixing root nodules
(via sciencedaily.com) Original source The developmental regulators that confer the identity of N-fixing root nodules belong to a transcription factor family (LSH) more commonly associated with defining the shapes of stems, flowers and leaves.
Published Shining a new light on the tug-of-war between virus and host
(via sciencedaily.com) Original source The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct interactions of individual RNA regions in an unbiased fashion without the need for genetic modification of the target RNA or cell. Researchers have now developed a breakthrough tool that overcomes this limitation.
Published Discovery of a third RNA virus linage in extreme environments Jan 17, 2024
(via sciencedaily.com) Original source A research group has discovered a novel RNA viral genome from microbes inhabiting a high-temperature acidic hot spring. Their study shows that RNA viruses can live in high-temperature environments (70-80 degrees Celsius), where no RNA viruses have been observed before. In addition to the two known RNA virus kingdoms, a third kingdom may exist.
Published Machine learning guides carbon nanotechnology
(via sciencedaily.com) Original source Carbon nanostructures could become easier to design and synthesize thanks to a machine learning method that predicts how they grow on metal surfaces. The new approach will make it easier to exploit the unique chemical versatility of carbon nanotechnology.
Published Groundbreaking genome editing tools unlock new possibilities for precision medicine
(via sciencedaily.com) Original source A team of researchers has achieved a major breakthrough in genome editing technology. They've developed a cutting-edge method that combines the power of designer-recombinases with programmable DNA-binding domains to create precise and adaptable genome editing tools.
Published How seahorse-like toxins kill insects
(via sciencedaily.com) Original source Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal 'Makes caterpillars floppy 1' (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery how Mcf1 unfolds its devastating effect. Researchers successfully used cryo-electron microscopy (cryo-EM) and biochemical assays to characterize the first-ever Mcf1 structure, allowing them to propose a molecular mechanism of the toxin's action. Understanding how bacterial toxins perform their deadly task in such detail is very useful for engineering novel biopesticides, thereby reducing the use of barely specific chemical agents with harmful side effects for the ecosystem.
Published Engineering viruses to kill deadly pathogens
(via sciencedaily.com) Original source Antimicrobial resistance is an urgent and growing global crisis. Researchers are exploring phages, viruses that infect bacteria, as a possible solution. In the new study, researchers successfully modified DNA from four types of phages to kill a deadly pathogen. The process can also be used to produce more phage variants for further exploration.
Published When and how immune cells decide to form pathogen memories
(via sciencedaily.com) Original source During infection, reversible switch permits flexible formation of memory T cells, long-lived blood cells that can remember pathogen encounters and respond upon reinfection.
Published Using computers to design proteins allows researchers to make tunable hydrogels that can form both inside and outside of cells
(via sciencedaily.com) Original source New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. These hydrogels exhibited similar mechanical properties both inside and outside of cells, providing researchers with a new tool to group proteins together inside of cells.
Published A green alternative for treating Streptococcus iniae bacteria in hybrid striped bass
(via sciencedaily.com) Original source Scientists have developed a green antibiotic alternative to treat the deadly pathogen Streptococcus iniae in hybrid striped bass, the fourth most farmed finfish in the United States, according to a recent study.