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Categories: Biology: Cell Biology, Engineering: Nanotechnology
Published Researchers develop DANGER analysis tool for the safer design of gene editing
(via sciencedaily.com) Original source A team of researchers has developed a software tool that provides a way for the safer design of genome editing in all organisms with a transcriptome. For about a decade, researchers have used the CRISPR technology for genome editing. However, there are some challenges in the use of CRISPR. The new analysis system overcomes these challenges and allows researchers to perform safer on- and off-target assessments without a reference genome. It holds the potential for applications in medicine, agriculture, and biological research.
Published Moving muscle fibers with magnets 'programs' how they align within tissue
(via sciencedaily.com) Original source Stimulating muscle fibers with magnets causes them to grow in the same direction, aligning muscle cells within tissue. The findings offer a simpler, less time-consuming way for medical researchers to program muscle cell alignment, which is strongly tied to healthy muscle function.
Published How cord-like aggregates of bacteria lead to tuberculosis infections
(via sciencedaily.com) Original source The ability of Mycobacterium tuberculosis (MTB), a serious respiratory infection, to form snake-like cords was first noted nearly 80 years ago. Investigators report the biophysical mechanisms by which these cords form and demonstrate how several generations of dividing bacteria hang together to create these structures that enable resistance to antibiotics.
Published Generating clean electricity with chicken feathers
(via sciencedaily.com) Original source Turning unused waste from food production into clean energy: Researchers are using chicken feathers to make fuel cells more cost-effective and sustainable.
Published Soil carried on sea freight loaded with dangerous pests and diseases, research finds
(via sciencedaily.com) Original source While sea freight is recognised as a pathway for the movement of exotic organisms, there is little research that has quantified the risk. Soil collected from the external surfaces of sea freight was found to support live microorganisms, worms, seeds and insects, including various regulated biosecurity organisms. The research confirms that shipping containers provide a pathway for the movement of exotic species.
Published Can golden retrievers live longer?
(via sciencedaily.com) Original source Researchers have found a gene associated with longevity in golden retrievers, one of the most popular breeds of dogs.
Published DNA shows where Washington culvert replacements helped spawning salmon
(via sciencedaily.com) Original source University and federal scientists used genetic sleuthing to study how salmon were affected by two major culvert replacements near the city of Bellingham. One project, a major upgrade under Interstate-5, had a big impact, while the other old culvert may have been less of a barrier to fish. Authors from the UW and NOAA are studying the use of environmental DNA, or eDNA, in future environmental impact reporting.
Published Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents
(via sciencedaily.com) Original source Whether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the 'parenting hub' in the brain, according to a new study.
Published International team develops novel DNA nano engine
(via sciencedaily.com) Original source An international team of scientists has recently developed a novel type of nano engine made of DNA. It is driven by a clever mechanism and can perform pulsing movements. The researchers are now planning to fit it with a coupling and install it as a drive in complex nano machines.
Published Red meat consumption associated with increased type 2 diabetes risk
(via sciencedaily.com) Original source People who eat just two servings of red meat per week may have an increased risk of developing type 2 diabetes compared to people who eat fewer servings, and the risk increases with greater consumption, according to a new study. Researchers also found that replacing red meat with healthy plant-based protein sources, such as nuts and legumes, or modest amounts of dairy foods, was associated with reduced risk of type 2 diabetes.
Published Physical theory improves protein folding prediction
(via sciencedaily.com) Original source Proteins are important molecules that perform a variety of functions essential to life. To function properly, many proteins must fold into specific structures. However, the way proteins fold into specific structures is still largely unknown. Researchers have developed a novel physical theory that can accurately predict how proteins fold. Their model can predict things previous models cannot. Improved knowledge of protein folding could offer huge benefits to medical research, as well as to various industrial processes.
Published Restoring the function of a human cell surface protein in yeast cells
(via sciencedaily.com) Original source Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into yeast cells. To tackle this issue, researchers developed an innovative strategy to restore GPCR function in yeast cells by inducing random mutations. Their findings can help understand GPCRs better and could pave the way to therapeutic breakthroughs for many diseases.
Published Electron-rich metals make ceramics tough to crack
(via sciencedaily.com) Original source Engineers have developed a recipe to make a certain class of ceramics tougher and more resistant to cracking. The newfound toughness of these ceramics paves the way for their use in extreme applications, such as spacecraft and other hypersonic vehicles.
Published Stolen genes allow parasitic control of behavior
(via sciencedaily.com) Original source A research team has discovered that parasites manipulate their hosts using stolen genes that they likely acquired through a phenomenon called horizontal gene transfer.
Published Soft optical fibers block pain while moving and stretching with the body
(via sciencedaily.com) Original source New soft, implantable fibers can deliver light to major nerves through the body. They are an experimental tool for scientists to explore the causes and potential treatments for peripheral nerve disorders in animal models.
Published Wearable device makes memories and powers up with the flex of a finger
(via sciencedaily.com) Original source Researchers have invented an experimental wearable device that generates power from a user's bending finger and can create and store memories, in a promising step towards health monitoring and other technologies.
Published Yeast speeds discovery of medicinal compounds in plants
(via sciencedaily.com) Original source Researchers have harnessed the power of baker's yeast to create a cost-effective and highly efficient approach for unraveling how plants synthesize medicinal compounds, and used the new method to identify key enzymes in a kratom tree.
Published Going rogue: Scientists apply giant wave mechanics on a nanometric scale
(via sciencedaily.com) Original source Researchers have shown how the principles of rogue waves -- huge 30-meter waves that arise unexpectedly in the ocean -- can be applied on a nano scale, with dozens of applications from medicine to manufacturing.
Published Study elucidates evolution of mosquitoes and their hosts
(via sciencedaily.com) Original source Study creates a mosquito family tree to better understand disease transmission and host choice.
Published Milestone: Miniature particle accelerator works
(via sciencedaily.com) Original source Particle accelerators are crucial tools in a wide variety of areas in industry, research and the medical sector. The space these machines require ranges from a few square meters to large research centers. Using lasers to accelerate electrons within a photonic nanostructure constitutes a microscopic alternative with the potential of generating significantly lower costs and making devices considerably less bulky. Until now, no substantial energy gains were demonstrated. In other words, it has not been shown that electrons really have increased in speed significantly. Two teams of laser physicists have just succeeded in demonstrating a nanophotonic electron accelerator.