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Categories: Biology: Cell Biology, Engineering: Nanotechnology
Published Creating supranormal hearing in mice



A new study has produced supranormal hearing in mice, while also supporting a hypothesis on the cause of hidden hearing loss in people.
Published The future of metals research with artificial intelligence



A research team has developed an optimal artificial intelligence model to predict the yield strength of various metals, effectively addressing traditional cost and time limitations.
Published Materials research revolutionized by a small change



Scientists develop the next generation of highly efficient memory materials with atom-level control.
Published Long-standing marine mystery solved: How algae get nitrogen to grow



Scientists shed light on an unexpected partnership: A marine diatom and a bacterium that can account for a large share of nitrogen fixation in vast regions of the ocean. This symbiosis likely plays a key role for global marine nitrogen fixation and productivity, and thus uptake of carbon dioxide. The newly-discovered bacterial symbiont is closely related to the nitrogen-fixing Rhizobia which live in partnership with many crop plants and may also open up new avenues for engineering nitrogen-fixing plants.
Published New deep-learning model outperforms Google AI system in predicting peptide structures



Researchers have developed a deep-learning model, called PepFlow, that can predict all possible shapes of peptides -- chains of amino acids that are shorter than proteins, but perform similar biological functions. Peptides are known to be highly flexible, taking on a wide range of folding patterns, and are thus involved in many biological processes of interest to researchers in the development of therapeutics.
Published Last surviving woolly mammoths were inbred but not doomed to extinction



The last population of woolly mammoths was isolated on Wrangel Island off the coast of Siberia 10,000 years ago, when sea levels rose and cut the mountainous island off from the mainland. A new genomic analysis reveals that the isolated mammoths, who lived on the island for the subsequent 6,000 years, originated from at most 8 individuals but grew to 200--300 individuals within 20 generations. The researchers report that the Wrangel Island mammoths' genomes showed signs of inbreeding and low genetic diversity but not to the extent that it can explain their ultimate (and mysterious) extinction.
Published Invasive ants spread by hitchhiking on everyday vehicles



Ants might spread to new locations by stowing away on everyday vehicles. Previously, this was thought to occur mostly on agricultural equipment.
Published A promising weapon against measles



What happens when measles virus meets a human cell? The viral machinery unfolds in just the right way to reveal key pieces that let it fuse itself into the host cell membrane.
Published Under pressure: How comb jellies have adapted to life at the bottom of the ocean



Researchers have studied the cell membranes of ctenophores ('comb jellies') and found they had unique lipid structures that allow them to live under intense pressure.
Published Potent therapy candidate for fatal prion diseases



Scientists have developed a gene-silencing tool that shows promise as a therapy against fatal prion diseases. The tool, a streamlined epigenetic editor, paves the way for a new class of genetic approaches to treat certain diseases.
Published New, holistic way to teach synthetic biology



Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.
Published Brain's 'escape switch' controlled by threat sensitivity dial



Neuroscientists have discovered how the brain bidirectionally controls sensitivity to threats to initiate and complete escape behaviour in mice. These findings could help unlock new directions for discovering therapies for anxiety and post-traumatic stress disorder (PTSD).
Published From takeoff to flight, the wiring of a fly's nervous system is mapped



Although a fly's motor neurons are few, it performs remarkable aerial and terrestrial feats. A wiring diagram recently created of the motor circuits in the central nervous system of the fruit fly is providing detailed information on how the nerve coordination of leg movements differs from that controlling the wings. Such studies reveal the unexpected complexity of the fly's tiny motor system. They also advance the understanding of how the central nervous system in animals coordinates individual muscles to carry out a variety of behaviors.
Published Scientists discover genetic 'off switch' in legume plants that limits biological ability to source nutrients



A genetic 'off switch' that shuts down the process in which legume plants convert atmospheric nitrogen into nutrients has been identified for the first time by a team of international scientists.
Published Cell division: Before commitment, a very long engagement



Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.
Published Unlocking the world of bacteria



Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species. A team has now introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.
Published Microrobot-packed pill shows promise for treating inflammatory bowel disease in mice



Engineers have developed a pill that releases microscopic robots, or microrobots, into the colon to treat inflammatory bowel disease (IBD). The experimental treatment, given orally, has shown success in mice. It significantly reduced IBD symptoms and promoted the healing of damaged colon tissue without causing toxic side effects.
Published The on-and-off affair in DNA



Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via the interactions of two other proteins and histone marks. The molecular mechanisms demonstrate that rather than functioning as a simple 'off switch,' H3K9 methylation is more like a 'dimmer switch' that fine-tunes DNA transcription. The discovery suggests there might be similar mechanisms in other organisms, too.
Published A new study highlights potential of ultrafast laser processing for next-gen devices



A new study uncovers the remarkable potential of ultrafast lasers that could provide innovative solutions in 2D materials processing for many technology developers such as high-speed photodetectors, flexible electronics, biohybrids, and next-generation solar cells.
Published Slipping a note to a neighbor: The cellular way



Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication.