Showing 20 articles starting at article 301
< Previous 20 articles Next 20 articles >
Categories: Biology: Cell Biology, Engineering: Nanotechnology
Published Where to put head and tail?
(via sciencedaily.com) Original source Formation of the body axes is a critical part of embryonic development. They guarantee that all body parts end up where they belong and that no ears grow on our backs. The head-tail axis, for example, determines the orientation of the two ends of the body. It was previously assumed that this axis is largely determined by the interplay between the Nodal and BMP signals. However, there appears to be another player in this system, as researchers have now discovered by using an embryo-like model system they developed. In the absence of BMP, the signalling molecule beta-catenin takes on the role of the Nodal antagonist. This new mechanism could be a flexible solution for axis formation in embryos with different shapes.
Published How the ketogenic diet improves healthspan and memory in aging mice
(via sciencedaily.com) Original source The ketogenic diet has its fanatics and detractors among dieters, but either way, the diet has a scientifically documented impact on memory in mice. While uncovering how the high fat, low carbohydrate diet boosts memory in older mice, scientists identified a new molecular signaling pathway that improves synapse function and helps explain the diet's benefit on brain health and aging.
Published A high-fat diet may fuel anxiety
(via sciencedaily.com) Original source New research shows when animals are fed a diet high in saturated fat for nine weeks, their gut bacteria change in ways that influence brain chemicals and fuel anxiety.
Published Novel method for measuring nano/microplastic concentrations in soil using spectroscopy
(via sciencedaily.com) Original source Current techniques for measuring nano/microplastic (N/MP) concentrations in soil require the soil organic matter content to be separated and have limited resolution for analyzing N/MPs sized <1 m. Therefore, researchers have developed a novel yet simple method to measure N/MP concentration in different soil types using spectroscopy at two wavelengths. This method does not require the soil to be separated in order to detect the N/MPs and can accurately quantify N/MPs regardless of their size.
Published Wear it, then recycle: Designers make dissolvable textiles from gelatin
(via sciencedaily.com) Original source Researchers hope their DIY machine will help designers around the world experiment with making their own, sustainable fashion and other textiles from a range of natural ingredients -- maybe even the chitin in crab shells or agar-agar from algae.
Published Golden ball mills as green catalysts
(via sciencedaily.com) Original source A gold-coated milling vessel for ball mills proved to be a real marvel: without any solvents or environmentally harmful chemicals, the team was able to use it to convert alcohols into aldehydes. The catalytic reaction takes place at the gold surface and is mechanically driven. The vessel can be reused multiple times. 'This opens up new prospects for the use of gold in catalysis and shows how traditional materials can contribute to solving modern environmental problems in an innovative way,' says Borchardt.
Published Previously uncharacterized parasite uncovered in fish worldwide
(via sciencedaily.com) Original source Using genome reconstruction, scientists unveiled a once 'invisible' fish parasite present in many marine fish world-wide that belongs to the apicomplexans, one of the most important groups of parasites at a clinical level. However, it had gone unnoticed in previous studies. The parasite is geographically and taxonomically widespread in fish species around the planet, with implications for commercial fishing and oceanic food webs.
Published Research into structures of ape hearts provide insight into human evolution
(via sciencedaily.com) Original source Researchers have discovered new insights into the human heart's structure, revealing its evolutionary history. This study enhances understanding of heart development and its implications for treating heart disease.
Published When bacteria are buckling
(via sciencedaily.com) Original source Filamentous cyanobacteria buckle at a certain length when they encounter an obstacle. The results provide an important basis for the use of cyanobacteria in modern biotechnology.
Published Nano-immunotherapy developed to improve lung cancer treatment
(via sciencedaily.com) Original source Researchers have developed a new nanomedicine therapy that delivers anticancer drugs to lung cancer cells and enhances the immune system's ability to fight cancer. The team showed promising results for the new therapy in cancer cells in the lab and in mouse lung tumor models, with potential applications for improving care and outcomes for patients with tumors that have failed to respond to traditional immunotherapy.
Published Vitamin B6: New compound delays degradation
(via sciencedaily.com) Original source A low vitamin B6 level has negative effects on brain performance. A research team has now found a way to delay the degradation of the vitamin.
Published The genetic 'switches' of bone growth
(via sciencedaily.com) Original source In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone. They are controlled by other sequences in the genome, called enhancers, which, like switches, activate or deactivate them as required. A team has now identified and located 2700 enhancers -- among millions of non-coding genetic sequences -- that precisely regulate the genes responsible for bone growth. This discovery sheds light on one of the major factors influencing the size of individuals in adulthood, and explains why their failure could be the cause of certain bone malformations.
Published Self-assembling and disassembling swarm molecular robots via DNA molecular controller
(via sciencedaily.com) Original source Researchers have succeeded in developing a DNA-based molecular controller. Crucially, this controller enables the autonomous assembly and disassembly of molecular robots, as opposed to manually directing it.
Published Study on architecture of heart offers new understanding of human evolution
(via sciencedaily.com) Original source An international research team has uncovered a new insight into human evolution by comparing humans' hearts with those of other great apes.
Published Fasting primes the immune system's natural killer cells to better fight cancer, new study in mice finds
(via sciencedaily.com) Original source A team of researchers has shown for the first time that fasting can reprogram the metabolism of natural killer cells, helping them to survive in the harsh environment in and around tumors, while also improving their cancer-fighting ability.
Published Infectious H5N1 influenza virus in raw milk rapidly declines with heat treatment
(via sciencedaily.com) Original source The amount of infectious H5N1 influenza viruses in raw milk rapidly declined with heat treatment in laboratory research. However, small, detectable amounts of infectious virus remained in raw milk samples with high virus levels when treated at 72 degrees Celsius (161.6 degrees Fahrenheit) for 15 seconds -- one of the standard pasteurization methods used by the dairy industry. The authors of the study stress, however, that their findings reflect experimental conditions in a laboratory setting and are not identical to large-scale industrial pasteurization processes for raw milk.
Published Scientists preserve DNA in an amber-like polymer
(via sciencedaily.com) Original source With their 'T-REX' method, researchers developed a glassy, amber-like polymer that can be used for long-term storage of DNA, such as entire human genomes or digital files such as photos.
Published Only one in 20 therapies tested in animals reach approval for human use
(via sciencedaily.com) Original source An analysis of reviews of translational biomedical research reveals that just 5% of therapies tested in animals reach regulatory approval for human use. The umbrella review summarizes other systematic reviews and provides high level evidence that while the rate of translation to human studies is 50%, there is steep drop off before final approval.
Published Modifying genomes of tardigrades to unravel their secrets
(via sciencedaily.com) Original source Some species of tardigrades are highly and unusually resilient to various extreme conditions fatal to most other forms of life. The genetic basis for these exceptional abilities remains elusive. Researchers have now successfully edited genes using the CRISPR technique in a highly resilient tardigrade species previously impossible to study with genome-editing tools. The successful delivery of CRISPR to an asexual tardigrade species directly produces gene-edited offspring. The design and editing of specific tardigrade genes allow researchers to investigate which are responsible for tardigrade resilience and how such resilience can work.
Published Nanosized blocks spontaneously assemble in water to create tiny floating checkerboards
(via sciencedaily.com) Original source Researchers have engineered nanosized cubes that spontaneously form a two-dimensional checkerboard pattern when dropped on the surface of water. The work presents a simple approach to create complex nanostructures through a technique called self-assembly.