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Categories: Biology: Cell Biology, Engineering: Nanotechnology

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Molecular biologists provide exciting insights into the bristles of the marine annelid worm Platynereis dumerilii. Specialized cells, so-called chaetoblasts, control the formation of the bristles. Their mode of operation is astonishingly similar to that of a technical 3D printer.

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Researchers have discovered that how soft or rigid proteins are in certain regions can dictate how fast or slow they enter the nucleus.

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Introns are perhaps one of our genome's biggest mysteries. They are DNA sequences that interrupt the sensible protein-coding information in your genes, and need to be 'spliced out.'

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Researchers have taken a key step toward closing the silver nanoparticles knowledge gap with a study that indicates the particles' shape and surface chemistry play key roles in how they affect aquatic ecosystems.

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The discovery of how a critical enzyme 'hidden in nature's blueprint' works sheds new light on how cells control key processes in carbon fixation, a process fundamental for life on Earth. The discovery could help engineer climate resilient crops capable of sucking carbon dioxide from the atmosphere more efficiently, helping to produce more food in the process.

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A research team has discovered how carboxysomes, carbon-fixing structures found in some bacteria and algae, work. The breakthrough could help scientists redesign and repurpose the structures to enable plants to convert sunlight into more energy, paving the way for improved photosynthesis efficiency, potentially increasing the global food supply and mitigating global warming.

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A research team has demonstrated that an iron-based amorphous alloy, widely used as a soft magnetic material in transformers and motors, can be transformed into a 'transverse' thermoelectric conversion material that converts electric and thermal currents in orthogonal directions, with just a short period of heat treatment. This is the first example that highlights the importance of microstructure engineering in the development of transverse thermoelectric conversion materials, and provides new design guidelines for materials development to realize environmentally friendly power generation and thermal management technologies using magnetic materials.

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A team has developed a vaccine approach that works like a GPS, guiding the immune system through the specific steps to make broadly neutralizing antibodies against HIV.

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Scientists have discovered a new partnership between a marine diatom and a bacterium that can account for a large share of nitrogen fixation in vast regions of the ocean. The newly-discovered bacterial symbiont is closely related to the nitrogen-fixing Rhizobia which live in partnership with many crop plants and may open up new avenues to engineer nitrogen-fixing plants.

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A 'crazy idea' hatched during a walk in the woods and first tested by a high school student is now an innovative research tool used by scientists worldwide to predict neurotransmitters in fruit fly connectomes.

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In a study of a species of African butterfly, researchers have discovered a previously undescribed molecular mechanism of how the sex of an embryo is initially specified.

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Scientists delve into the composition of nanocomposites for ultraviolet metasurface fabrication.

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Nature has consistently inspired engineering applications. Recently, a group of researchers drew new inspirations from the vascular network and developed a new type of fluidic system named VasFluidics.

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A recent study led to the development of a powerful epigenetic editing technology. The system unlocks the ability to precisely program chromatin modifications at any specific position in the genome, to understand their causal role in transcription regulation. This innovative approach will help to investigate the role of chromatin modifications in many biological processes, and to program desired gene activity responses, which may prove useful in disease settings.

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Adjuvants make vaccines more effective, though one of the best is an expensive extract from the soap bark tree. To lower the cost and avoid the laborious extraction process from bark, synthetic biologists introduced 38 separate genes into yeast to recreate the synthesis of the active molecule, a complex chemical, QS-21, that has a terpene core and numerous sugars. This may be the longest biosynthetic pathway ever inserted into yeast.

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Freshwater bacteria with small genomes frequently undergo prolonged periods of adaptive stagnation. Based on genomic analyses of samples from European lakes, researchers uncovered specific evolutionary strategies that shape these bacteria's lifestyles. Understanding the evolutionary dynamics of aquatic microbial communities is key to safeguarding ecosystem services.

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When old food packaging, discarded children's toys and other mismanaged plastic waste break down into microplastics, they become even harder to clean up from oceans and waterways. These tiny bits of plastic also attract bacteria, including those that cause disease. Researchers describe swarms of microscale robots (microrobots) that captured bits of plastic and bacteria from water. Afterward, the bots were decontaminated and reused.

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Tracking individual enzymes during the breakdown of cellulose for biofuel production has revealed how several roadblocks slow this process when using plant material that might otherwise go to waste. The research may lead to new ways to improve the breakdown process and make the non-edible parts of plants and other plant waste, such as forestry residue, a more competitive source of biofuels.

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Move over, graphene. There's a new, improved two-dimensional material in the lab. Borophene, the atomically thin version of boron first synthesized in 2015, is more conductive, thinner, lighter, stronger and more flexible than graphene, the 2D version of carbon. Now, researchers have made the material potentially more useful by imparting chirality -- or handedness -- on it, which could make for advanced sensors and implantable medical devices.

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Fatty liver disease often leads to chronic liver inflammation and can even result in liver cancer. Scientists have now shown in mice that intermittent fasting on a 5:2 schedule can halt this development. The fasting regime reduces the development of liver cancer in mice with pre-existing liver inflammation. The researchers identified two proteins in liver cells that are jointly responsible for the protective effect of fasting. An approved drug can partially mimic this effect.