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Categories: Biology: Cell Biology, Engineering: Nanotechnology
Published Connecting the dots to shape growth forces
(via sciencedaily.com) Original source Branching patterns are prevalent in our natural environment and the human body, such as in the lungs and kidneys. For example, specific genes that express growth factor proteins are known to influence the development of the lungs' complex branches. Researchers have unveiled a regulatory system linking signal, force, and shape in mouse lung structure development. The team recognized that the signal protein ERK plays an active role in causing growing lung tissue to curve.
Published Synaptic protein change during development offers clues on evolution and disease
(via sciencedaily.com) Original source An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The findings offer first insights into the mechanism behind synaptic development and open up routes for research on possible treatments.
Published New method developed to isolate HIV particles
(via sciencedaily.com) Original source Researchers have developed a new method to isolate HIV from samples more easily, potentially making it easier to detect infection with the virus. They focus on peptide nanofibrils (PNFs) on magnetic microparticles, a promising tool and hybrid material for targeted binding and separation of viral particles.
Published A combination of approved drugs enhances the delivery of anti-bacterial medications to treat tuberculosis
(via sciencedaily.com) Original source Researchers have found that approved drugs that were originally shown to normalize blood vessels surrounding tumors (to improve drug delivery to cancer cells) can enhance the delivery of anti-microbial medications to kill tuberculosis bacteria residing in the lungs.
Published Scientists extract genetic secrets from 4,000-year-old teeth to illuminate the impact of changing human diets over the centuries
(via sciencedaily.com) Original source Researchers have recovered remarkably preserved microbiomes from two teeth dating back 4,000 years, found in an Irish limestone cave. Genetic analyses of these microbiomes reveal major changes in the oral microenvironment from the Bronze Age to today. The teeth both belonged to the same male individual and also provided a snapshot of his oral health.
Published A tiny spot leads to a large advancement in nano-processing, researchers reveal
(via sciencedaily.com) Original source Focusing a tailored laser beam through transparent glass can create a tiny spot inside the material. Researchers have reported on a way to use this small spot to improve laser material processing, boosting processing resolution.
Published New technique for predicting protein dynamics may prove big breakthrough for drug discovery
(via sciencedaily.com) Original source Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers has developed a way of using machine learning to rapidly predict multiple protein configurations to advance understanding of protein dynamics and functions.
Published New enzymatic cocktail can kill tuberculosis-causing mycobacteria
(via sciencedaily.com) Original source An enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis.
Published Researchers create biocompatible nanoparticles to enhance systemic delivery of cancer immunotherapy
(via sciencedaily.com) Original source Researchers are enhancing immunotherapy effects against malignant tumors by developing and validating patent-ending poly (lactic-co-glycolic acid), or PLGA, nanoparticles modified with adenosine triphosphate, or ATP.
Published Milk on ice: Antarctic time capsule of whole milk powder sheds light on the enduring qualities--and evolution--of dairy products past and present
(via sciencedaily.com) Original source In a remarkable discovery, whole milk powder manufactured in New Zealand in 1907 and transported to Antarctica with explorers seeking the South Pole was unveiled after more than a century. The find has allowed dairy researchers to answer the question: Is the milk we enjoy today different from the milk consumed in previous generations? Now, a new comparative study has peered back in time to demonstrate that -- despite advancements in selective breeding and changes to farm practices -- milk of the past and milk today share more similarities than differences and are still crucial building blocks of human nutrition.
Published Old immune systems revitalized in mouse study, improving vaccine response
(via sciencedaily.com) Original source Those with aging immune systems struggle to fight off novel viruses and respond weakly to vaccination. Researchers were able to revitalize the immune system in mice.
Published Super permeable wearable electronics developed for stable, long-term biosignal monitoring
(via sciencedaily.com) Original source Super wearable electronics that are lightweight, stretchable and increase sweat permeability by 400-fold have been developed by scientists, enabling reliable long-term monitoring of biosignals for biomedical devices.
Published New testing approach improves detection of rare but emerging Powassan virus spread by deer ticks
(via sciencedaily.com) Original source Researchers have come up with a new, more accurate method for detecting in ticks the emerging Powassan virus, which can cause life-threatening neuroinvasive disease, including encephalitis and meningitis.
Published Researchers show that introduced tardigrade proteins can slow metabolism in human cells
(via sciencedaily.com) Original source Tardigrade proteins are potential candidates in technologies centered on slowing the aging process and in long-term storage of human cells.
Published New method to measure entropy production on the nanoscale
(via sciencedaily.com) Original source Entropy, the amount of molecular disorder, is produced in several systems but cannot be measured directly. A new equation sheds new light on how entropy is produced on a very short time scale in laser excited materials.
Published Silicon spikes take out 96% of virus particles
(via sciencedaily.com) Original source An international research team has designed and manufactured a virus-killing surface that could help control disease spread in hospitals, labs and other high-risk environments.
Published Discovery of amino acid unveils how light makes plants open
(via sciencedaily.com) Original source Scientists have uncovered a unique mechanism that regulates the opening of stomata in plants. Phosphorylation of the amino acid Thr881 on the plasma membrane proton pump plays a key role in this process. The study paves the way for the targeted manipulation of plant physiology, with potential applications in agriculture and environmental sustainability.
Published Micro-Lisa! Making a mark with novel nano-scale laser writing
(via sciencedaily.com) Original source High-power lasers are often used to modify polymer surfaces to make high-tech biomedical products, electronics and data storage components. Now researchers have discovered a light-responsive, inexpensive sulfur-derived polymer is receptive to low power, visible light lasers -- promising a more affordable and safer production method in nanotech, chemical science and patterning surfaces in biological applications.
Published Research lights up process for turning CO2 into sustainable fuel
(via sciencedaily.com) Original source Researchers have successfully transformed CO2 into methanol by shining sunlight on single atoms of copper deposited on a light-activated material, a discovery that paves the way for creating new green fuels.
Published Novel electrochemical sensor detects dangerous bacteria
(via sciencedaily.com) Original source Researchers have developed a novel sensor for the detection of bacteria. It is based on a chip with an innovative surface coating. This ensures that only very specific microorganisms adhere to the sensor -- such as certain pathogens. The larger the number of organisms, the stronger the electric signal generated by the chip. In this way, the sensor is able not only to detect dangerous bacteria with a high level of sensitivity but also to determine their concentration.