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Categories: Biology: Cell Biology, Engineering: Nanotechnology
Published GPT-4 for identifying cell types in single cells matches and sometimes outperforms expert methods



GPT-4 can accurately interpret types of cells important for the analysis of single-cell RNA sequencing -- a sequencing process fundamental to interpreting cell types -- with high consistency compared to that of time-consuming manual annotation by human experts of gene information.
Published Breakthrough antibiotic shows promise against obstinate mycobacterial infections



A team of scientists has developed a novel antibiotic named COE-PNH2 that is capable of combating hard-to-treat mycobacterial lung infections. Such infections, which are notorious for resisting conventional treatment, pose a serious health threat, especially to the elderly and those with underlying conditions.
Published A self-cleaning wall paint



Beautiful white wall paint does not stay beautiful and white forever. Often, various substances from the air accumulate on its surface. This can be a desired effect because it makes the air cleaner for a while -- but over time, the color changes and needs to be renewed. Now, special titanium oxide nanoparticles have been developed that can be added to ordinary, commercially available wall paint to establish self-cleaning power: The nanoparticles are photocatalytically active, they can use sunlight not only to bind substances from the air, but also to decompose them afterwards.
Published Humans pass more viruses to other animals than we catch from them



Humans pass on more viruses to domestic and wild animals than we catch from them, according to a major new analysis of viral genomes.
Published Quantum interference could lead to smaller, faster, and more energy-efficient transistors



Scientists made a single-molecule transistor using quantum interference to control electron flow. This new design offers high on/off ratio and stability, potentially leading to smaller, faster, and more energy-efficient devices. Quantum interference also improves the transistor's sensitivity to voltage changes, further boosting its efficiency.
Published Researchers discover evolutionary 'tipping point' in fungi



Scientists have found a 'tipping point' in the evolution of fungi that throttles their growth and sculpts their shapes. The findings demonstrate how small changes in environmental factors can lead to huge changes in evolutionary outcomes.
Published Natural recycling at the origin of life



How was complex life able to develop on the inhospitable early Earth? At the beginning there must have been ribonucleic acid (RNA) to carry the first genetic information. To build up complexity in their sequences, these biomolecules need to release water. On the early Earth, which was largely covered in seawater, that was not so easy to do.
Published Scientists close in on TB blood test which could detect millions of silent spreaders



Millions of people are spreading tuberculosis unknowingly - now scientists say they are close to developing a new test that is as simple as the lateral flows used during the Covid pandemic.
Published Signs of life would be detectable in single ice grain emitted from extraterrestrial moons



Could life be found in frozen sea spray from moons orbiting Saturn or Jupiter? New research finds that life can be detected in a single ice grain containing one bacterial cell or portions of a cell. The results suggest that if life similar to that on Earth exists on these planetary bodies, that this life should be detectable by instruments launching in the fall.
Published As we age, our cells are less likely to express longer genes



Aging may be less about specific 'aging genes' and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers. A decline in the expression of long genes with age has been observed in a wide range of animals, from worms to humans, in various human cell and tissue types, and also in individuals with neurodegenerative disease. Mouse experiments show that the phenomenon can be mitigated via known anti-aging factors, including dietary restriction.
Published Research finds a direct communication path between the lungs and the brain



New research finds a direct communication path between the lungs and the brain which may change the way we treat respiratory infections and chronic conditions. The lungs are using the same sensors and neurons in the pain pathway to let the brain know there's an infection. The brain then prompts the symptoms associated with sickness. Findings indicate we may have to treat the nervous system as well as the infection.
Published Natural molecule found in coffee and human body increases NAD+ levels, improves muscle function during aging



A research consortium made a recent discovery that the natural molecule trigonelline present in coffee, fenugreek, and also in the human body, can help to improve muscle health and function.
Published Decoding the plant world's complex biochemical communication networks



A research team has begun translating the complex molecular language of petunias. Their grammar and vocabulary are well hidden, however, within the countless proteins and other compounds that fill floral cells. Being rooted to the ground, plants can't run away from insects, pathogens or other threats to their survival. But plant scientists have long known that they do send warnings to each other via scent chemicals called volatile organic compounds.
Published In-situ observation of nanoscale heat propagation



A research team has developed a technique that enables the nanoscale observation of heat propagation paths and behavior within material specimens. This was achieved using a scanning transmission electron microscope (STEM) capable of emitting a pulsed electron beam and a nanosized thermocouple -- a high-precision temperature measurement device.
Published Scientists weigh up current status of blue whale populations around the world



The largest living animal, the blue whale (Balaenoptera musculus) which averages about 27 meters in length, has slowly recovered from whaling only to face the rising challenges of global warming, pollution, disrupted food sources, shipping, and other human threats. In a major new study, biologists have taken a stock of the number, distribution and genetic characteristics of blue whale populations around the world and found the greatest differences among the eastern Pacific, Antarctic subspecies and pygmy subspecies of the eastern Indian and western Pacific.
Published Deep Earth electrical grid mystery solved



To 'breathe' in an environment without oxygen, bacteria in the ground beneath our feet depend upon a single family of proteins to transfer excess electrons, produced during the 'burning' of nutrients, to electric hairs called nanowires projecting from their surface.
Published Bacteria subtype linked to growth in up to 50% of human colorectal cancers



Researchers have found that a specific subtype of a microbe commonly found in the mouth is able to travel to the gut and grow within colorectal cancer tumors. This microbe is also a culprit for driving cancer progression and leads to poorer patient outcomes after cancer treatment. The findings could help improve therapeutic approaches and early screening methods for colorectal cancer, which is the second most common cause of cancer deaths in adults in the U.S. according to the American Cancer Society.
Published Robotic metamaterial: An endless domino effect



If it walks like a particle, and talks like a particle... it may still not be a particle. A topological soliton is a special type of wave or dislocation which behaves like a particle: it can move around but cannot spread out and disappear like you would expect from, say, a ripple on the surface of a pond. Researchers now demonstrate the atypical behavior of topological solitons in a robotic metamaterial, something which in the future may be used to control how robots move, sense their surroundings and communicate.
Published Crawfish could transfer ionic lithium from their environment into food chain



Lithium-ion rechargeable batteries are showing up in ever more devices, and the increasing use of this technology means more lithium is expected to find its way into the environment as a contaminant. In new research, a team has explored how this ion accumulates in a common Southern crustacean, the crawfish, with implications for the environment and public health.
Published Craving snacks after a meal? It might be food-seeking neurons, not an overactive appetite



Psychologists have discovered a circuit in the brain of mice that makes them crave food and seek it out, even when they are not hungry. When stimulated, this cluster of cells propels mice to forage vigorously and to prefer fatty and pleasurable foods like chocolate over healthier foods like carrots.