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Categories: Biology: Cell Biology, Engineering: Nanotechnology
Published Steroid drugs used for HRT can combat E. coli and MRSA
(via sciencedaily.com) Original source Researchers have combined computational and microbiology laboratory approaches to identify existing drugs that can be repurposed to combat antibiotic-resistant bacterial infections. This research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.
Published New computational strategy boosts the ability of drug designers to target proteins inside the membrane
(via sciencedaily.com) Original source Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.
Published Simple trick could improve accuracy of plant genetics research
(via sciencedaily.com) Original source Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables -- such as temperature -- affect gene activity in plants.
Published Milk to the rescue for diabetics? Cow produces human insulin in milk
(via sciencedaily.com) Original source An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.
Published A simple and robust experimental process for protein engineering
(via sciencedaily.com) Original source A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.
Published Scientists find weak points on Epstein-Barr virus
(via sciencedaily.com) Original source Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.
Published Spiral wrappers switch nanotubes from conductors to semiconductors and back
(via sciencedaily.com) Original source By wrapping a carbon nanotube with a ribbon-like polymer, researchers were able to create nanotubes that conduct electricity when struck with low-energy light that our eyes cannot see. In the future, the approach could make it possible to optimize semiconductors for applications ranging from night vision to new forms of computing.
Published Have metalenses expanded their reach into the ultraviolet region?
(via sciencedaily.com) Original source A team achieves successful mass production of metalenses designed for application in the ultraviolet region.
Published How a natural compound from sea squirts combats cancer
(via sciencedaily.com) Original source Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.
Published A coral superhighway in the Indian Ocean
(via sciencedaily.com) Original source Despite being scattered across more than a million square kilometers, new research has revealed that remote coral reefs across the Seychelles are closely related. Using genetic analyses and oceanographic modelling, researchers demonstrated for the first time that a network of ocean currents scatter significant numbers of larvae between these distant islands, acting as a 'coral superhighway.'
Published Gene flow in giraffes and what it means for their conservation
(via sciencedaily.com) Original source Giraffes, with their bizarre body plan, have always held a special place in the minds of evolutionary biologists and non-experts alike. In a new study whole-genome sequencing data was used to investigate the evolutionary processes occurring within giraffes. In particular, the authors were interested in establishing whether different populations of giraffes really have been isolated from each other for extended periods of time, which is normally a requirement before new species can arise.
Published Giving particle detectors a boost
(via sciencedaily.com) Original source Researchers have tested the performance of a new device that boosts particle signals.
Published GPS nanoparticle platform precisely delivers therapeutic payload to cancer cells
(via sciencedaily.com) Original source A newly developed 'GPS nanoparticle' injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers. They tested their approach in human cell lines and in mice to effectively knock down a cancer-causing gene, reporting that the technique may potentially offer a more precise and effective treatment for notoriously hard-to-treat basal-like breast cancers.
Published Study illuminates the protective role of fluorescence in neon-colored sea anemones
(via sciencedaily.com) Original source A team of researchers has uncovered a direct genetic link between fluorescence and color in sea anemones -- those soft and tentacled tide pool creatures often encountered by beachgoers.
Published New study reveals transgenerational effects of pesticide linuron on frogs
(via sciencedaily.com) Original source Grand-offspring of male frogs exposed to the pesticide linuron exhibited changes in their DNA that was linked to significant physiological impacts, a study reveals. The research highlights the profound transgenerational consequences of environmental pollution on amphibian populations, which are already under threat of extinction.
Published Researchers uncover protein responsible for cold sensation
(via sciencedaily.com) Original source Researchers have identified the protein that enables mammals to sense cold, filling a long-standing knowledge gap in the field of sensory biology.
Published Muscaris grapes: Molecular secret of lychee note revealed
(via sciencedaily.com) Original source Researchers have succeeded in identifying the odorants responsible for the characteristic lychee note of Muscaris grapes.
Published Breakthrough in nanostructure technology for real-time color display
(via sciencedaily.com) Original source New groundbreaking technology enables the real-time display of colors and shapes through changes in nanostructures.
Published Anemonefish are better taxonomists than humans
(via sciencedaily.com) Original source Scientists reveal new lineages of giant sea anemones in Japan and their surprising associations with anemonefish.
Published 'Molecular Rosetta Stone' reveals how our microbiome talks to us
(via sciencedaily.com) Original source Researchers have uncovered thousands of previously unknown bile acids, a type of molecule used by our gut microbiome to communicate with the rest of the body.