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Categories: Biology: Cell Biology, Physics: General

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The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct interactions of individual RNA regions in an unbiased fashion without the need for genetic modification of the target RNA or cell. Researchers have now developed a breakthrough tool that overcomes this limitation.

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Researchers describe the discovery of a new method that transforms everyday materials like glass into materials scientists can use to make quantum computers.

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A research group has discovered a novel RNA viral genome from microbes inhabiting a high-temperature acidic hot spring. Their study shows that RNA viruses can live in high-temperature environments (70-80 degrees Celsius), where no RNA viruses have been observed before. In addition to the two known RNA virus kingdoms, a third kingdom may exist.

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A joint research team has successfully induced polarization and polarity in metallic substances.

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Carbon nanostructures could become easier to design and synthesize thanks to a machine learning method that predicts how they grow on metal surfaces. The new approach will make it easier to exploit the unique chemical versatility of carbon nanotechnology.

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A team of researchers has achieved a major breakthrough in genome editing technology. They've developed a cutting-edge method that combines the power of designer-recombinases with programmable DNA-binding domains to create precise and adaptable genome editing tools.

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Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal 'Makes caterpillars floppy 1' (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery how Mcf1 unfolds its devastating effect. Researchers successfully used cryo-electron microscopy (cryo-EM) and biochemical assays to characterize the first-ever Mcf1 structure, allowing them to propose a molecular mechanism of the toxin's action. Understanding how bacterial toxins perform their deadly task in such detail is very useful for engineering novel biopesticides, thereby reducing the use of barely specific chemical agents with harmful side effects for the ecosystem.

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Antimicrobial resistance is an urgent and growing global crisis. Researchers are exploring phages, viruses that infect bacteria, as a possible solution. In the new study, researchers successfully modified DNA from four types of phages to kill a deadly pathogen. The process can also be used to produce more phage variants for further exploration.

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Researchers have developed a pioneering method to precisely manipulate ultrafast spin waves in antiferromagnetic materials using tailored light pulses.

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During infection, reversible switch permits flexible formation of memory T cells, long-lived blood cells that can remember pathogen encounters and respond upon reinfection.

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New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. These hydrogels exhibited similar mechanical properties both inside and outside of cells, providing researchers with a new tool to group proteins together inside of cells.

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An international team has developed a new method to make and manipulate a widely studied class of high-temperature superconductors. This technique should pave the way for the creation of unusual forms of superconductivity in previously unattainable materials.

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Scientists have developed a green antibiotic alternative to treat the deadly pathogen Streptococcus iniae in hybrid striped bass, the fourth most farmed finfish in the United States, according to a recent study.

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Every fluid -- from Earth's atmosphere to blood pumping through the human body -- has viscosity, a quantifiable characteristic describing how the fluid will deform when it encounters some other matter. If the viscosity is higher, the fluid flows calmly, a state known as laminar. If the viscosity decreases, the fluid undergoes the transition from laminar to turbulent flow. The degree of laminar or turbulent flow is referred to as the Reynolds number, which is inversely proportional to the viscosity. However, this Reynolds similitude does not apply to quantum superfluids. A researcher has theorized a way to examine the Reynolds similitude in superfluids, which could demonstrate the existence of quantum viscosity in superfluids.

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Using a DNA-based delivery particle, researchers created a vaccine that can induce a strong antibody response against SARS-CoV-2.

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How is a beech leaf constructed? What determines the appearance of an asparagus? A new 'encyclopaedia' helps us learn more about the building blocks of plants. The encyclopaedia, probably the largest of its kind, could be used to improve targeted plant breeding efforts, to make them both more climate-resilient and more easily digestible.

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Scientists have succeeded in cultivating and characterizing tomato varieties with higher water use efficiency without compromising yield. The researchers, employing CRISPR genetic editing technology, were able to grow tomatoes that consume less water while preserving yield, quality, and taste.

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Nanoclusters (NCs) of transition metals like cobalt or nickel have widespread applications in drug delivery and water purification, with smaller NCs exhibiting improved functionalities. Downsizing NCs is, however, usually challenging. Now, scientists have demonstrated functional NC formation with atomic-scale precision. They successfully grew cobalt NCs on flat copper surfaces using molecular arrays as traps. This breakthrough paves the way for advancements like single-atom catalysis and spintronics miniaturization.

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Researchers are currently developing anti-viral surfaces to decrease the spread of infectious diseases. A recent study found that a resin ingredient is effective against coronaviruses and strongly decreases their infectivity on plastic surfaces.

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Poultry scientists are unraveling the complexities of bird brains and finding less expensive ways to do it. The scientists mapped the intricate neurological pathways that control vision in chickens with detailed 3D models of the connections between the eyes and four regions of the brain.