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Categories: Biology: Cell Biology, Physics: General
Published Perfecting 3D-printed blood vessels with pores



Due to the substantial clinical demand for artificial small-diameter vessels (SDVs), numerous commercial products have emerged. However, the majority of existing artificial SDVs lack an endothelial layer, leading to thrombosis. Fabricating artificial SDVs with a consistently uniform endothelial layer and adequate mechanical properties has proven exceptionally challenging. A research team has now induced spontaneous cell assembly and endothelialization through internal pores.
Published Surprisingly simple model explains how brain cells organize and connect



A new study by physicists and neuroscientists describes how connectivity among neurons comes about through general principles of networking and self-organization, rather than the biological features of an individual organism.
Published A non-proliferation solution: Using antineutrinos to surveil nuclear reactors



Antineutrinos generated in nuclear fission can be measured to remotely monitor the operation of nuclear reactors and verify that they are not being used to produce nuclear weapons, report scientists. Thanks to a newly developed method, it is now possible to estimate a reactor's operation status, fuel burnup, and fuel composition based entirely on its antineutrino emissions. This technique could contribute massively to nuclear non-proliferation efforts and, in turn, safer nuclear energy.
Published Long live the graphene valley state



Researchers found evidence that bilayer graphene quantum dots may host a promising new type of quantum bit based on so-called valley states.
Published Glowing COVID-19 diagnostic test prototype produces results in one minute



Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.
Published New technology for conducting deep-sea research on fragile organisms



Scientists have successfully demonstrated new technologies that can obtain preserved tissue and high-resolution 3D images within minutes of encountering some of the most fragile animals in the deep ocean.
Published The surface knows what lies beneath: Physicists show how to detect higher-order topological insulators



Just like a book can't be judged by its cover, a material can't always be judged by its surface. But, for an elusive conjectured class of materials, physicists have now shown that the surface previously thought to be 'featureless' holds an unmistakable signature that could lead to the first definitive observation.
Published Silkmoths: Different olfactory worlds of females and males



Female moths primarily use their sense of smell to find the best host plants on which to lay their eggs, with the deterrent effect of caterpillar feces playing an important role, according to new research.
Published Tests can reveal whether an antibody can turn into a killer



A promising antibody failed testing. This is good news for developing a broad-spectrum antidote against the world's most dangerous snake venoms.
Published Unraveling the role of supersulfides in regulating mitochondrial function and longevity



Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.
Published Physicists identify overlooked uncertainty in real-world experiments



The rules of statistical physics address the uncertainty about the state of a system that arises when that system interacts with its environment. But they've long missed another kind. In a new paper, researchers argue that uncertainty in the thermodynamic parameters themselves -- built into equations that govern the energetic behavior of the system -- may also influence the outcome of an experiment.
Published Solid-state qubits: Forget about being clean, embrace mess



New findings debunk previous wisdom that solid-state qubits need to be super dilute in an ultra-clean material to achieve long lifetimes. Instead, cram lots of rare-earth ions into a crystal and some will form pairs that act as highly coherent qubits, a new paper shows.
Published Bioinformatics: Researchers develop a new machine learning approach



To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published A novel pathway regulating lipid biosynthesis by fatty acids



Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.
Published New insights into what helps Salmonella cause infections



In a new study, researchers have discovered how a system of proteins, called TamAB, helps Salmonella survive under the harsh conditions inside macrophages.
Published 3D in vitro human atherosclerosis model for high-throughput drug screening



A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging



Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published New rice lines for Africa offer virus protection



The so-called Rice Yellow Mottle Virus (for short: RYMV) is responsible for high crop losses in Africa, particularly among small-scale farmers. A research team has now produced rice lines that are resistant to the disease by means of genome editing. The rice varieties are a preliminary step toward being able to generate resistant locally adapted elite varieties for small-scale food producers in Africa.
Published Spying on a shape-shifting protein



Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases.
Published How fruit flies smell carbon dioxide



Mosquitoes in search of blood as well as fruit flies looking for a place to lay their eggs navigate using carbon dioxide, which is produced during respiration or in fermentation processes. A complex of various odor receptors that can detect CO2 has already been identified in mosquitoes. Researchers have now shown that individual receptors found in fruit flies can also detect CO2. They also identified molecules that blocked the CO2 receptors.