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Categories: Biology: Cell Biology, Physics: General

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Bile acids long have been known to play a role in human metabolism. Synthesized from cholesterol in the liver, bile acids are involved in digestive processes, particularly in absorbing fat. They also are modified extensively by bacteria, which greatly expand the types of bile acids found in the host. For most of a century, scientists believed that was the end of the bile-acid story. Recent technological advances, however, have led to a greater understanding of the origins of bile acids as well as their chemical relationships to the organisms in the gut microbiome and their host.

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Neuroscientists say they have found a new function for the SYNGAP1 gene, a DNA sequence that controls memory and learning in mammals, including mice and humans.

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Scientists have discovered that viruses that infect microbes contribute to climate change by playing a key role in cycling methane, a potent greenhouse gas, through the environment.

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Keratin microsphere gel, consisting of keratin-based microspheres that swell in water to form a gel, has shown efficacy in promoting hair follicle growth in murine models. Its potential application as an active ingredient in hair regrowth treatments with minimal side effects is anticipated.

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Researchers have developed an innovative methodology for measuring the electrical conductivity of microbial communities. This methodology holds promise for the development of batteries and electrochemical sensors using microorganisms and may serve as a pivotal tool in elucidating the role of electricity within microbial ecosystems.

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Individually tailored RNA or DNA-based molecules are able to reliably fight off viral infections in plants, according to a new study. The researchers were able to fend off a common virus using the new active substances in up to 90 per cent of cases. They also developed a method for finding substances tailored specifically to the virus. The team has now patented the method.

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Researchers have recovered gold from electronic waste. Their highly sustainable new method is based on a protein fibril sponge, which the scientists derive from whey, a food industry byproduct.

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Improved neutron mirrors can increase the efficiency of material analysis in neutron sources such as the ESS. The improved mirror has been developed by coating a silicon plate with extremely thin layers of iron and silicon mixed with boron carbide.

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Playing a different sound track is, physically speaking, only a minute change of the vibration spectrum, yet its impact on a dance floor is dramatic. People long for this tiny trigger, and as a salsa changes to a tango completely different collective patterns emerge. For such a tiny stimulus to have an effect, the crowd needs to know more than just one dance. Electrons in metals tend to show only one behavior at zero temperature, when all kinetic energy is quenched.

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New research provides compelling evidence that partially substituting animal with plant protein foods can increase life expectancy and decrease greenhouse gas emissions. Importantly, it also suggests that benefits depend on the type of animal protein being replaced. The study drew data from a national nutrition survey to analyze Canadians' dietary records. The study modeled partial replacements (25% and 50%) of either red and processed meat or dairy with plant protein foods like nuts, seeds, legumes, tofu, and fortified soy beverages, on a combination of nutrition, health, and climate outcomes.

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Researchers have clarified the evolutionary history of a previously poorly known group of ferns from the tropical rainforests of America using DNA methods. The study discovered many new fern species, 18 of which have now been given official names and species descriptions.

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Researchers report that the Golgi ribbon, an organelle structure previously thought to be exclusive to vertebrates, is also present in animal taxa, including mollusks, earthworms, and sea urchins. The function of the Golgi ribbon is still enigmatic, but its presence in diverse animal lineages indicates that its function is not vertebrate specific, as previously thought. The team also showed Golgi ribbons form at a specific timepoint during embryogenesis, which suggests that they might play a role in cell differentiation.

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New phospholipid discovery brings researchers closer to understanding how primordial cells emerged during origin of life.

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Scientists have extensively researched the structure and sequence of genetic material and its interactions with proteins in the hope of understanding how our genetics and environment interact in diseases. This research has partly focused on 'epigenetic marks', which are chemical modifications to DNA, RNA, and the associated proteins (known as histones).

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The eyes have been called the window to the brain. It turns out they also serve as an immunological barrier that protects the organ from pathogens and even tumors, researchers have found. In a new study, researchers showed that vaccines injected into the eyes of mice can help disable the herpes virus, a major cause of brain encephalitis. To their surprise, the vaccine activates an immune response through lymphatic vessels along the optic nerve.

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Researchers think they have a foundational tool for the thorny problem of how to measure and image the behavior of hydride superconductors at high pressure. They report creatively integrating quantum sensors into a diamond anvil cell, enabling direct readouts of the pressurized material's electrical and magnetic properties.

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Scientists have found a new way to alter the DNA of bacterial cells -- a process used to make many vital medicines including insulin -- much more efficiently than standard industry techniques.

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Researchers have developed a microporous covalent organic framework with dense donor-acceptor lattices and engineered linkages for the efficient and clean production of hydrogen peroxide through the photosynthesis process with water and air.

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Molecules that are induced by light to rotate bulky groups around central bonds could be developed into photo-activated bioactive systems, molecular switches, and more.

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Researchers have discovered that thin films of elemental bismuth exhibit the so-called non-linear Hall effect, which could be applied in technologies for the controlled use of terahertz high-frequency signals on electronic chips. Bismuth combines several advantageous properties not found in other systems to date, as the team reports. Particularly: the quantum effect is observed at room temperature. The thin-layer films can be applied even on plastic substrates and could therefore be suitable for modern high-frequency technology applications.