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Categories: Biology: Cell Biology, Computer Science: Virtual Reality (VR)

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The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model predicting cellular behavior. Such universal principles now allow a better understanding of the migration of immune and cancer cells, paving the way for new treatment options.

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A novel mixed light field technique that utilizes a mix of ray-controlled ambient lighting with projection mapping (PM) to obtain PM in bright surroundings has been developed by scientists. This innovative technology utilizes a novel kaleidoscope array to achieve ray-controlled lighting and a binary search algorithm for removing ambient lighting from PM targets. It provides an immersive augmented reality experience with applications in various fields.

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Depicting worst-case climate scenarios like expanding deserts and dying coral reefs may better motivate people to support environmental policies when delivered via virtual reality, according to a research team that studied how VR and message framing affect the impact of environmental advocacy communications. The study findings may help advocacy groups decide how best to frame and deliver their messages.

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In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured and compared with the pH of nearby non-nucleolar condensates including nuclear speckles and Cajal bodies.

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Eating fatty food in the days leading up to surgery may prompt a heightened inflammatory response in the brain that interferes for weeks with memory-related cognitive function in older adults -- and, new research in animals suggests, even in young adults.

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Research has demonstrated individual differences in and successfully extracted commonalities from the whole-brain activity of roundworms. The researchers also found that computer simulations based on the whole-brain activity of roundworms more accurately reflect real-brain activity when they include so-called 'noise,' or probabilistic elements.

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Researchers have created a DNA origami platform called DoriVac, whose core component is a self-assembling square block-shaped nanostructure. DoriVac vaccines enabled tumor-bearing mice to better control the growth of tumors and to survive significantly longer than control mice.

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Making a personalized T cell therapy for cancer patients currently takes at least six months. Scientists have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.

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Perfectly adapted microorganisms live in extreme environments from deep-sea trenches to mountaintops. Learning more about how these extremophiles survive in hostile conditions could inform scientists about life on Earth and potential life on other planets.

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Automated insulin dosing systems combine low-cost blood-glucose monitors with insulin pumps that use precision dosing to continuously regulate blood-sugar and hold it steady. Synthetic biologists have found a way to piggyback on the technology and make it universally applicable for the precision dosing of virtually any drug.

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It is known that large amounts of licorice cause high blood pressure. A new study now shows that even small amounts of licorice raise blood pressure. The individuals who react most strongly also show signs of strain on the heart.

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Researchers have discovered a link between gut bacteria and the success of milk-allergy oral immunotherapy. The study found that Bifidobacterium -- a genus of beneficial bacteria in the gut -- was associated with a higher chance of successful treatment. The finding may help in the development of more effective oral immunotherapies, perhaps by combining them with probiotic supplements.

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Scientists are exploring how tuning the genomes of mushrooms and molds can transform these food sources into gourmet, nutrient-packed meals made with minimal processing and a light environmental footprint.

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Researchers combined artificial intelligence and chemical biosensors to ferment the precursor of an Alzheimer's drug in bacteria.

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A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus responsible for COVID-19. The study focuses on the design and development of a novel protein capable of binding to the spike proteins found on the surface of the coronavirus. The goal behind this innovative approach is twofold: first, to identify and recognize the virus for diagnostic purposes, and second, to hinder its ability to infect human cells.

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Researchers have discovered that some fish -- unlike humans -- do not need orexin to stay awake. This molecule was thought to be necessary for normal wake and sleep rhythms in vertebrates. Humans without orexin suffer from narcolepsy.

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After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo, a new study finds. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.

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Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide a contact site for another protein, Tank-binding kinase 1 (TBK1), during this process. The OPTN-TBK1 relationship is necessary for these mitochondria to be recognized and eliminated from the cell. This mechanism may have relevance for developing drugs to treat Parkinson's disease.

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Research has found a less expensive and easier to use test to learn more about forensic touch DNA. This research has important implications for forensic investigations and being able to identify DNA from a primary contact -- someone who may have committed the crime -- as well as secondary DNA that was inadvertently and indirectly transferred through touch.

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A new study shines a spotlight on sulfur, a chemical element that, while all familiar, has proved surprisingly resistant to scientific efforts in probing its role in the origin of life.