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Categories: Biology: Cell Biology, Mathematics: Puzzles
Published Invasive ants spread by hitchhiking on everyday vehicles



Ants might spread to new locations by stowing away on everyday vehicles. Previously, this was thought to occur mostly on agricultural equipment.
Published A promising weapon against measles



What happens when measles virus meets a human cell? The viral machinery unfolds in just the right way to reveal key pieces that let it fuse itself into the host cell membrane.
Published Under pressure: How comb jellies have adapted to life at the bottom of the ocean



Researchers have studied the cell membranes of ctenophores ('comb jellies') and found they had unique lipid structures that allow them to live under intense pressure.
Published Potent therapy candidate for fatal prion diseases



Scientists have developed a gene-silencing tool that shows promise as a therapy against fatal prion diseases. The tool, a streamlined epigenetic editor, paves the way for a new class of genetic approaches to treat certain diseases.
Published New, holistic way to teach synthetic biology



Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.
Published Brain's 'escape switch' controlled by threat sensitivity dial



Neuroscientists have discovered how the brain bidirectionally controls sensitivity to threats to initiate and complete escape behaviour in mice. These findings could help unlock new directions for discovering therapies for anxiety and post-traumatic stress disorder (PTSD).
Published From takeoff to flight, the wiring of a fly's nervous system is mapped



Although a fly's motor neurons are few, it performs remarkable aerial and terrestrial feats. A wiring diagram recently created of the motor circuits in the central nervous system of the fruit fly is providing detailed information on how the nerve coordination of leg movements differs from that controlling the wings. Such studies reveal the unexpected complexity of the fly's tiny motor system. They also advance the understanding of how the central nervous system in animals coordinates individual muscles to carry out a variety of behaviors.
Published Scientists discover genetic 'off switch' in legume plants that limits biological ability to source nutrients



A genetic 'off switch' that shuts down the process in which legume plants convert atmospheric nitrogen into nutrients has been identified for the first time by a team of international scientists.
Published Cell division: Before commitment, a very long engagement



Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.
Published Unlocking the world of bacteria



Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species. A team has now introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.
Published The on-and-off affair in DNA



Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via the interactions of two other proteins and histone marks. The molecular mechanisms demonstrate that rather than functioning as a simple 'off switch,' H3K9 methylation is more like a 'dimmer switch' that fine-tunes DNA transcription. The discovery suggests there might be similar mechanisms in other organisms, too.
Published Slipping a note to a neighbor: The cellular way



Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication.
Published Towards non-toxic antifouling agents: A novel method for total synthesis of scabrolide F



Norcembranolide diterpenes, isolated from the soft corals of the genus Sinularia, are important compounds for the development of new drugs, owing to their diverse biological activities. However, total synthesis methods for these compounds are scarce. Now, a team of researchers has achieved the total synthesis of scabrolide F, a norcembranolide diterpene. They also revealed its non-toxic antifouling properties. This novel method can lead to the development of new drugs and antifouling agents.
Published Revealing the dynamic choreography inside multilayer vesicles



Our cells and the machinery inside them are engaged in a constant dance. This dance involves some surprisingly complicated choreography within the lipid bilayers that comprise cell membranes and vesicles -- structures that transport waste or food within cells. In a recent paper, researchers shed some light on how these vesicles self-assemble, knowledge that could help scientists design bio-inspired vesicles for drug-delivery or inspire them to create life-like synthetic materials.
Published Rewriting the armadillo family tree: A new species, plus a name change for the state mammal of Texas



The nine-banded armadillo, which ranges all the way from Argentina to Nebraska, is actually four separate species. One of the species, the Guianan long-nosed armadillo, is new to science. Meanwhile, the species that has migrated from Mexico to the United States (and is the official small mammal of Texas) is now called the Mexican long-nosed armadillo.
Published Zebrafish reveal how bioelectricity shapes muscle development



New research describes how nerve cells and muscle cells communicate through electrical signals during development -- a phenomenon known as bioelectricity. The communication, which takes place via specialized channels between cells, is vital for proper development and behavior. The study identifies specific genes that control the process, and pins down what happens when it goes wrong. The finding offers clues to the genetic origins of muscle disorders in humans.
Published Non-stop flight: 4,200 km transatlantic flight of the Painted Lady butterfly mapped



In October 2013 a researcher made a surprising discovery of Painted Lady Butterflies on the Atlantic beaches of French Guiana -- a species not typically found in South America. This unusual sighting prompted an international study to investigate the origin of these butterflies.
Published Discovery of vast sex differences in cellular activity has major implications for disease treatment



The study reveals vast differences in gene activity within the mitochondria of males compared to females. This is the first study to test effects of all 37 genes in the mitochondrial genome -- genes that copepods and humans share. The study found that males demonstrate more activity across all protein-coding mitochondrial genes than females. Although the study looks at tiny marine organisms called copepods, the findings have weighty implications for human medicine.
Published 3D-printed chip sensor detects foodborne pathogens for safer products



Researchers have developed a new method for detecting foodborne pathogens that is faster, cheaper, and more effective than existing methods. Their microfluidic chip uses light to detect multiple types of pathogens simultaneously and is created using 3D printing, making it easy to fabricate in large amounts and modify to target specific pathogens. The researchers hope their technique can improve screening processes and keep contaminated food out of the hands of consumers.
Published Should you eat more dietary fiber? New study says it depends



Nutritionists generally advise everyone to eat more dietary fiber, but a new study suggests that its effects on health can vary from person to person. The findings indicate that recommendations should be tailored to each individual's gut microbiome.