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Categories: Biology: Cell Biology, Ecology: Extinction
Published Mining the microbiome: Uncovering new antibiotics inside the human gut



Researchers surveyed the gut microbiomes of nearly 2,000 people, discovering dozens of potential new antibiotics. The lead candidate, prevotellin-2, demonstrated anti-infective capabilities on par with polymyxin B, an FDA-approved antibiotic used today to treat multidrug-resistant infections, suggesting that the human gut microbiome may contain antibiotics that will someday find clinical application.
Published Ancient DNA reveals Indigenous dog lineages found at Jamestown, Virginia



Previous scientific studies have indicated that North American dog lineages were replaced with European ones between 1492 and the present day. To better understand the timing of this replacement, researchers sequenced mitochondrial DNA from archaeological dogs. Their findings suggest a complex social history of dogs during the early colonial period.
Published Knocking out one key gene leads to autistic traits



Hyperactivity, repetitive behavior, and language deficits all appeared in the mice, highlighting an unexpected role the cerebellum seems to play in autism.
Published Rethinking the dodo



Researchers are setting out to challenge our misconceptions about the Dodo, one of the most well-known but poorly understood species of bird. Researchers have undertaken the most comprehensive review of the taxonomy of the Dodo and its closest relative, the Rodriguez Island Solitaire.
Published The banana apocalypse is near, but biologists might have found a key to their survival



The bananas in your supermarket and that you eat for breakfast are facing functional extinction due to the disease Fusarium wilt of banana (FWB) caused by a fungal pathogen called Fusarium oxysporum f.sp. cubense (Foc) tropical race 4 (TR4). However, thanks to recent research from an international team of scientists we now know that Foc TR4 did not evolve from the strain that wiped out commercial banana crops in the 1950s and that the virulence of this new strain seems to be caused by some accessory genes that are associated the production of nitric oxide. The research opens the door to treatments and strategies that can slow, if not control, the as-of-yet unchecked spread of Foc TR4.
Published Probiotics during pregnancy shown to help moms and babies



Giving probiotics to pregnant mice can enhance both the immune system and behavior of the mothers and their offspring.
Published As human activities expand in Antarctica, scientists identify crucial conservation sites



Establishing Key Biodiversity Areas in the Southern Ocean will be vital for safeguarding the ecosystem from the impact of human activities, researchers say.
Published Nearly 25% of European landscape could be rewilded, researchers say



Europe's abandoned farmlands could find new life through rewilding, a movement to restore ravaged landscapes to their wilderness before human intervention. A quarter of the European continent, 117 million hectares, is primed with rewilding opportunities, researchers report.
Published Zebrafish use surprising strategy to regrow spinal cord



A new study maps out a detailed atlas of all the cells involved in regenerating the zebrafish spinal cord. In an unexpected finding, the researchers showed that survival and adaptability of the severed neurons themselves is required for full spinal cord regeneration. Surprisingly, the study showed that stem cells capable of forming new neurons play a complementary role but don t lead the process.
Published Surprise finding in study of environmental bacteria could advance search for better antibiotics



Researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial cell's 'envelope' or enclosure is key to its survival, the finding could advance the search for new and better antibiotics.
Published Scientists map DNA of Lyme disease bacteria



Researchers have produced a genetic analysis of Lyme disease bacteria that may pave the way for improved diagnosis, treatment, and prevention of the tick-borne ailment.
Published Diet is main risk factor for colon cancer in younger adults, new study suggests



A new study has identified diet-derived molecules called metabolites as main drivers of young-onset colorectal cancer risk, especially those associated with red and processed meat. The report, which analyzed metabolite and microbiome datasets, highlighted that one of the best ways a younger (less than 60 years) adult can prevent colorectal cancer is to discuss their diet with their doctor.
Published A taste for carbon dioxide



The remarkable affinity of the microbial enzyme iron nitrogenase for the greenhouse gas CO2 makes it promising for future biotechnologies.
Published New way inflammation impacts cell communication



Researchers have made significant progress in understanding how cells communicate during inflammation.
Published Revealing the mysteries within microbial genomes



A new technique will make it much easier for researchers to discover the traits or activities encoded by genes of unknown function in microbes, a key step toward understanding the roles and impact of individual species within the planet's diverse microbiomes.
Published Beige fat cells with a 'Sisyphus mechanism'



A new class of fat cells makes people healthier. The cells consume energy and produce heat through seemingly pointless biochemical reactions.
Published New mechanism of action kills cancer cells



Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the drugs ineffective. A research team now describes a new mechanism of action that kills cancer cells through ferroptosis.
Published C-section antibiotics impact the infant microbiome far less than infant diet



Caesarean section recipients are usually given prophylactic antibiotics just before the procedure to prevent later infections at the surgical site. But there have been concerns about whether these antibiotics may have a negative impact on newborns and their microbiomes if the drugs travel through the umbilical cord and reach the baby before the cord is cut. Now, a study has confirmed that although these antibiotics can cause subtle changes to the infant microbiome, they are much less significant than the impact of how the babies are fed.
Published A ketogenic diet could improve the response to pancreatic cancer therapy



Scientists have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer therapy.
Published Decoding the world's largest animal genome



Scientists have sequenced the largest genome of all animals, the lungfish genome. Their data help to explain how the fish-ancestors of today's land vertebrates were able to conquer land.