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Categories: Biology: Cell Biology, Ecology: Animals
Published Pilot study shows ketogenic diet improves severe mental illness
(via sciencedaily.com) Original source A small clinical trial found that the metabolic effects of a ketogenic diet may help stabilize the brain.
Published Do sweeteners increase your appetite? New evidence from randomised controlled trial says no
(via sciencedaily.com) Original source Replacing sugar with artificial and natural sweeteners in foods does not make people hungrier -- and also helps to reduce blood sugar levels, a significant new study has found. The double blind randomized controlled trial found that consuming food containing sweeteners produced a similar reduction in appetite sensations and appetite-related hormone responses as sugary foods -- and provides some benefits such as lowering blood sugar, which may be particularly important in people at risk of developing type 2 diabetes. The use of sweeteners in place of sugar in foods can be controversial due to conflicting reports about their potential to increase appetite. Previous studies have been carried out but did not provide robust evidence. However, the researchers say their study, which meets the gold standard level of proof in scientific investigation, provides very strong evidence that sweeteners and sweetness enhancers do not negatively impact appetite and are beneficial for reducing sugar intake.
Published When inequality is more than 'skin-deep': Social status leaves traces in the epigenome of spotted hyenas in Tanzania
(via sciencedaily.com) Original source A research consortium provides evidence that social behavior and social status are reflected at the molecular level of gene activation (epigenome) in juvenile and adult free-ranging spotted hyenas. They analyzed non-invasively collected gut epithelium samples from both high-ranking and low-ranking female hyenas and showed that rank differences were associated with epigenetic signatures of social inequality, i.e., the pattern of activation or switching off of genes that regulate important physiological processes such as energy conversion and immune response in several genome regions.
Published How the Crimean-Congo hemorrhagic fever virus enters our cells
(via sciencedaily.com) Original source Researchers have identified how the tick-borne Crimean-Congo haemorrhagic fever virus enters our cells. The results are an important step in the development of drugs against the deadly disease.
Published Genomic research may help explain cancer resistance in Tasmanian devils
(via sciencedaily.com) Original source Through DNA sequencing of Tasmanian devils and their tumors, researchers have tracked the genomic interactions between the animals and the cancer.
Published New imaging method illuminates oxygen's journey in the brain
(via sciencedaily.com) Original source A new bioluminescence imaging technique has created highly detailed, and visually striking, images of the movement of oxygen in the brains of mice. The method, which can be easily replicated by other labs, will enable researchers to more precisely study forms of hypoxia in the brain, such as the denial of oxygen to the brain that occurs during a stroke or heart attack. The new research tool is already providing insight into why a sedentary lifestyle may increase risk for diseases like Alzheimer's.
Published Researchers discover key gene for toxic alkaloid in barley
(via sciencedaily.com) Original source Barley is one of the most important cereal crops on a global scale. Many barley cultivars produce a toxic alkaloid called gramine that affects the suitability of barley as fodder, but also helps to protect barley from pathogens. So far, the potential of manipulating gramine levels has not been harnessed for plant breeding, because the genetic basis of gramine production has been unresolved. Research groups now disclose the complete biosynthetic pathway of gramine and demonstrate how gramine biosynthesis can be introduced into model organisms or removed from barley.
Published Cell division quality control 'stopwatch' uncovered
(via sciencedaily.com) Original source Biologists have uncovered a quality control timing mechanism tied to cell division. The 'stopwatch' function keeps track of mitosis and acts as a protective measure when the process takes too long, preventing the formation of cancerous cells.
Published Small birds spice up the already diverse diet of spotted hyenas in Namibia
(via sciencedaily.com) Original source Hyenas are generalist predators (and scavengers) with a broad range of prey species. They are known for hunting (or scavenging) larger mammals such as antelopes and occasionally feed on smaller mammals and reptiles. Being flexible in the choice of prey is a strategy of generalists -- and this even extends to small passerine birds, as scientists observed in Namibia: Spotted hyenas pursued red-billed queleas, picked them from the ground or the surface of a waterhole and swallowed them whole, at a success rate of approximately one bird every three minutes.
Published Lyrebird synchronizes elements of its mating dance
(via sciencedaily.com) Original source To woo a mate, the Albert's Lyrebird of Australia becomes a real song-and-dance bird. Each male first chooses a stage of entangled vines, then in performance he shakes the vines as part of his courtship footwork, synchronizing each shake with the beat of his striking song.
Published Eggs may not be bad for your heart after all
(via sciencedaily.com) Original source Whether you like your eggs sunny-side up, hard boiled or scrambled, many hesitate to eat them amid concerns that eggs may raise cholesterol levels and be bad for heart health. However, results from a prospective, controlled trial show that over a four-month period cholesterol levels were similar among people who ate fortified eggs most days of the week compared with those who didn't eat eggs.
Published Connecting the dots to shape growth forces
(via sciencedaily.com) Original source Branching patterns are prevalent in our natural environment and the human body, such as in the lungs and kidneys. For example, specific genes that express growth factor proteins are known to influence the development of the lungs' complex branches. Researchers have unveiled a regulatory system linking signal, force, and shape in mouse lung structure development. The team recognized that the signal protein ERK plays an active role in causing growing lung tissue to curve.
Published Synaptic protein change during development offers clues on evolution and disease
(via sciencedaily.com) Original source An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The findings offer first insights into the mechanism behind synaptic development and open up routes for research on possible treatments.
Published New method developed to isolate HIV particles
(via sciencedaily.com) Original source Researchers have developed a new method to isolate HIV from samples more easily, potentially making it easier to detect infection with the virus. They focus on peptide nanofibrils (PNFs) on magnetic microparticles, a promising tool and hybrid material for targeted binding and separation of viral particles.
Published Understanding cattle grazing personalities may foster sustainable rangelands
(via sciencedaily.com) Original source New research finds that not all cattle are the same when it comes to grazing, and knowing that could lead to better animal health and range conditions.
Published A combination of approved drugs enhances the delivery of anti-bacterial medications to treat tuberculosis
(via sciencedaily.com) Original source Researchers have found that approved drugs that were originally shown to normalize blood vessels surrounding tumors (to improve drug delivery to cancer cells) can enhance the delivery of anti-microbial medications to kill tuberculosis bacteria residing in the lungs.
Published North American cities may see a major species turnover by the end of the century
(via sciencedaily.com) Original source Climate change may dramatically affect the animal species observed in North American cities, according to a new study.
Published Scientists extract genetic secrets from 4,000-year-old teeth to illuminate the impact of changing human diets over the centuries
(via sciencedaily.com) Original source Researchers have recovered remarkably preserved microbiomes from two teeth dating back 4,000 years, found in an Irish limestone cave. Genetic analyses of these microbiomes reveal major changes in the oral microenvironment from the Bronze Age to today. The teeth both belonged to the same male individual and also provided a snapshot of his oral health.
Published New technique for predicting protein dynamics may prove big breakthrough for drug discovery
(via sciencedaily.com) Original source Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers has developed a way of using machine learning to rapidly predict multiple protein configurations to advance understanding of protein dynamics and functions.
Published Combination of the climate crisis and continued deforestation may result in significant damage to the animal world
(via sciencedaily.com) Original source A new study states that the combination of global warming and extreme heat events, alongside the continued expansion of deforestation in the world, may be devastating for many species of animals, especially those that know how to climb trees. As part of the study, the researchers focused on lizards and showed that following the effects of climate change, they will seek refuge from the hot ground by spending a lot of time on trees. However, due to human-related activities, such as deforestation, urbanization and the expansion of agricultural lands at the expense of natural lands, the availability of trees in the areas where the lizards live will decrease, and this may lead to the collapse of many populations.