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Categories: Biology: Cell Biology, Ecology: Endangered Species
Published Mining the microbiome: Uncovering new antibiotics inside the human gut
(via sciencedaily.com) Original source Researchers surveyed the gut microbiomes of nearly 2,000 people, discovering dozens of potential new antibiotics. The lead candidate, prevotellin-2, demonstrated anti-infective capabilities on par with polymyxin B, an FDA-approved antibiotic used today to treat multidrug-resistant infections, suggesting that the human gut microbiome may contain antibiotics that will someday find clinical application.
Published Ancient DNA reveals Indigenous dog lineages found at Jamestown, Virginia
(via sciencedaily.com) Original source Previous scientific studies have indicated that North American dog lineages were replaced with European ones between 1492 and the present day. To better understand the timing of this replacement, researchers sequenced mitochondrial DNA from archaeological dogs. Their findings suggest a complex social history of dogs during the early colonial period.
Published Knocking out one key gene leads to autistic traits
(via sciencedaily.com) Original source Hyperactivity, repetitive behavior, and language deficits all appeared in the mice, highlighting an unexpected role the cerebellum seems to play in autism.
Published Probiotics during pregnancy shown to help moms and babies
(via sciencedaily.com) Original source Giving probiotics to pregnant mice can enhance both the immune system and behavior of the mothers and their offspring.
Published As human activities expand in Antarctica, scientists identify crucial conservation sites
(via sciencedaily.com) Original source Establishing Key Biodiversity Areas in the Southern Ocean will be vital for safeguarding the ecosystem from the impact of human activities, researchers say.
Published Nearly 25% of European landscape could be rewilded, researchers say
(via sciencedaily.com) Original source Europe's abandoned farmlands could find new life through rewilding, a movement to restore ravaged landscapes to their wilderness before human intervention. A quarter of the European continent, 117 million hectares, is primed with rewilding opportunities, researchers report.
Published Zebrafish use surprising strategy to regrow spinal cord
(via sciencedaily.com) Original source A new study maps out a detailed atlas of all the cells involved in regenerating the zebrafish spinal cord. In an unexpected finding, the researchers showed that survival and adaptability of the severed neurons themselves is required for full spinal cord regeneration. Surprisingly, the study showed that stem cells capable of forming new neurons play a complementary role but don t lead the process.
Published Surprise finding in study of environmental bacteria could advance search for better antibiotics
(via sciencedaily.com) Original source Researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial cell's 'envelope' or enclosure is key to its survival, the finding could advance the search for new and better antibiotics.
Published Scientists map DNA of Lyme disease bacteria
(via sciencedaily.com) Original source Researchers have produced a genetic analysis of Lyme disease bacteria that may pave the way for improved diagnosis, treatment, and prevention of the tick-borne ailment.
Published Why do plants wiggle? New study provides answers
(via sciencedaily.com) Original source Decades after his voyage on the HMS Beagle, Charles Darwin became fascinated by why plants move as they grow -- spinning and twisting into corkscrews. Now, more than 150 years later, a new study may have solved the riddle.
Published Diet is main risk factor for colon cancer in younger adults, new study suggests
(via sciencedaily.com) Original source A new study has identified diet-derived molecules called metabolites as main drivers of young-onset colorectal cancer risk, especially those associated with red and processed meat. The report, which analyzed metabolite and microbiome datasets, highlighted that one of the best ways a younger (less than 60 years) adult can prevent colorectal cancer is to discuss their diet with their doctor.
Published A taste for carbon dioxide
(via sciencedaily.com) Original source The remarkable affinity of the microbial enzyme iron nitrogenase for the greenhouse gas CO2 makes it promising for future biotechnologies.
Published New way inflammation impacts cell communication
(via sciencedaily.com) Original source Researchers have made significant progress in understanding how cells communicate during inflammation.
Published Revealing the mysteries within microbial genomes
(via sciencedaily.com) Original source A new technique will make it much easier for researchers to discover the traits or activities encoded by genes of unknown function in microbes, a key step toward understanding the roles and impact of individual species within the planet's diverse microbiomes.
Published Beige fat cells with a 'Sisyphus mechanism'
(via sciencedaily.com) Original source A new class of fat cells makes people healthier. The cells consume energy and produce heat through seemingly pointless biochemical reactions.
Published New mechanism of action kills cancer cells
(via sciencedaily.com) Original source Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the drugs ineffective. A research team now describes a new mechanism of action that kills cancer cells through ferroptosis.
Published C-section antibiotics impact the infant microbiome far less than infant diet
(via sciencedaily.com) Original source Caesarean section recipients are usually given prophylactic antibiotics just before the procedure to prevent later infections at the surgical site. But there have been concerns about whether these antibiotics may have a negative impact on newborns and their microbiomes if the drugs travel through the umbilical cord and reach the baby before the cord is cut. Now, a study has confirmed that although these antibiotics can cause subtle changes to the infant microbiome, they are much less significant than the impact of how the babies are fed.
Published A ketogenic diet could improve the response to pancreatic cancer therapy
(via sciencedaily.com) Original source Scientists have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer therapy.
Published Decoding the world's largest animal genome
(via sciencedaily.com) Original source Scientists have sequenced the largest genome of all animals, the lungfish genome. Their data help to explain how the fish-ancestors of today's land vertebrates were able to conquer land.
Published Researchers call for genetically diverse models to drive innovation in drug discovery
(via sciencedaily.com) Original source Researchers unveiled an approach to drug discovery that could revolutionize how we understand and treat diseases. Their commentary explains the limitations of studies using traditional mouse models and proposes using genetically diverse mice and mouse and human cells to better predict human responses to drugs and diseases.