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Categories: Biology: Cell Biology, Ecology: Sea Life
Published Butterfly and moth genomes mostly unchanged despite 250 million years of evolution



Comparison of over 200 high-quality butterfly and moth genomes reveals key insights into their biology, evolution and diversification over the last 250 million years, as well as clues for conservation.
Published Citizen science to mitigate the environmental crisis in the marine environment



Citizen science can help to improve conservation and management strategies for Mediterranean marine ecosystems, and to mitigate the impact of the environmental crisis.
Published An awkward family reunion: Sea monsters are our cousins



The sea lamprey, a 500-million-year-old animal with a sharp-toothed suction cup for a mouth, is the thing of nightmares. A new study discovered that the hindbrain -- the part of the brain controlling vital functions like blood pressure and heart rate -- of both sea lampreys and humans is built using an extraordinarily similar molecular and genetic toolkit.
Published Mercury levels in tuna remain nearly unchanged since 1971



Tuna is one of the most popular seafoods worldwide. But this protein-rich fish can build up high levels of methylmercury from feeding on contaminated prey, like smaller fish or crustaceans. Despite efforts to reduce mercury emissions into the environment, researchers report that levels in tuna appear to be unchanged since 1971. They warn that more aggressive emission reduction targets are needed to start nudging down tuna mercury levels.
Published Kiss-and-tell: A new method for precision delivery of nanoparticles and small molecules to individual cells



The delivery of experimental materials to individual cells with exactness and exclusivity has long been an elusive and much sought-after ability in biology. With it comes the promise of deciphering many longstanding secrets of the cell. A research team has now successfully shown how small molecules and single nanoparticles can be applied directly onto the surface of cells. In the study the scientists describe their technique as a ' kiss' (microkiss) -- an easy and cost-effective new method, unlocking new possibilities in single-cell science with a view towards next generation therapeutic applications.
Published An environmentally friendly way to turn seafood waste into value-added products



Reduce, reuse, recycle, and repurpose: These are all ways we can live more sustainably. One tricky aspect of recycling, though, is that sometimes the recycling process is chemically intensive, and this is the case for recycling one of the world's most abundant materials -- chitin. Researchers have tackled this problem and found a way to sustainably recover chitin from seafood waste.
Published Toxic elements found in stranded whales, dolphins over 15 years



Researchers evaluated the prevalence, concentration and tissue distribution of essential and non-essential trace elements, including heavy metal toxicants in tissue (blubber, kidney, liver, skeletal muscle, skin) and fecal samples collected from 90 whales and dolphins stranded in Georgia and Florida from 2007 to 2021.
Published Links between human, canine brain tumors



Researchers have discovered that meningiomas -- the most common type of brain tumor in humans and dogs -- are extremely similar genetically.
Published Baleen whales evolved a unique larynx to communicate but cannot escape human noise



The iconic baleen whales, such as the blue, gray and humpback whale, depend on sound for communication in the vast marine environment where they live. Now researchers have for the first time found that baleen whales evolved novel structures in their larynx to make their vast array of underwater songs.
Published New system triggers cellular waste disposal



Established treatments for cancer and other diseases often focus on inhibiting harmful enzymes to mitigate their effects. However, a more innovative approach has emerged: harnessing the cell's natural waste disposal system not just to deactivate but to entirely eradicate these proteins. Researchers have previously demonstrated the efficacy of this approach through two distinct methods. Now they unveil a third system capable of targeting and disposing of previously inaccessible proteins.
Published Detecting pathogens faster and more accurately by melting DNA



A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
Published Gulf corals still suffering more than a decade after Deepwater Horizon oil spill, scientists report



Deep-water corals in the Gulf of Mexico are still struggling to recover from the devastating Deepwater Horizon oil spill in 2010, scientists report at the Ocean Science Meeting in New Orleans. Comparing images of more than 300 corals over 13 years -- the longest time series of deep-sea corals to date -- reveals that in some areas, coral health continues to decline to this day.
Published Bridging diet, microbes, and metabolism: Implications for metabolic disorders



Mounting evidence suggests that the secret to understanding human health and combating metabolic diseases lies hidden within the microscopic world of our gut bacteria. Recent research reveals that a specific fatty acid produced by gut bacteria directly influences fat metabolism in animals. This research is pivotal as it sheds light on the complex interplay between the diet, gut microbiota, and host metabolic health, offering insights that could open new avenues in our approach to managing metabolic disorders.
Published Photosynthetic mechanism of purple sulfur bacterium adapted to low-calcium environments



Purple sulfur bacteria (PSB) convert light energy into chemical energy through photosynthesis. Interestingly, certain species can photosynthesize even in environments with low-calcium levels. Using cryo-electron microscopy, researchers unveiled the structure of light-harvesting complexes and elucidated the mechanism that facilitates photosynthesis under low-calcium conditions.
Published Breakthrough in developing the PD-1-enhanced DNA vaccine for over 6-year cART-free AIDS prevention and virologic control



Researchers found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years and achieved virologic control without the need for combination antiretroviral therapy (cART), a treatment used to suppress viral replication in individuals living with human immunodeficiency virus (HIV). The study also found that polyfunctional and broadly reactive effector-memory virus-specific T cells were maintained in the protected experimental macaques for over six years. The findings provide supporting evidence that the PD-1-enhanced DNA vaccine strategy holds promise as a third-generation DNA vaccine for AIDS prevention and immunotherapy.
Published Researchers are using RNA in a new approach to fight HIV



A pharmacy associate professor has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.
Published Using metabolomics for assessing safety of chemicals may reduce the use of lab rats



Scientists have discovered a more robust way of grouping chemicals and using read-across for toxicological data to meet regulatory requirements, which could greatly reduce animal testing.
Published It's the spin that makes the difference



Biomolecules such as amino acids and sugars occur in two mirror-image forms -- in all living organisms, however, only one is ever found. Why this is the case is still unclear. Researchers have now found evidence that the interplay between electric and magnetic fields could be at the origin of this phenomenon.
Published New model identifies drugs that shouldn't be taken together



Researchers have developed a multipronged strategy to identify the transporters used by different drugs. Their approach, which makes use of both tissue models and machine-learning algorithms, has already revealed that a commonly prescribed antibiotic and a blood-thinner can interfere with each other.
Published Unlocking the energetic secrets of collective animal movement: How group behavior reduces energy costs in fish



Researchers questioned if coordinated group movements by animals moving through a fluid could reduce the energy cost of locomotion. By combining biomechanics and bioenergetics the researchers found not only a significant amount of energy conservation, but also identified the reduced energy use per tail beat.